Enjoy the world

Rozchild looked at Hua Zhenxing for a long time, and finally sighed and said: "I didn't want to say too much at first, but I'm afraid you won't understand some things."

Hua Zhenxing said with a straight face: "Just because I can escort you on foot through the wilderness does not mean that I am just an ignorant savage."

Rozchild: "Well, I have to say goodbye tomorrow, and I will tell you today. Port Fiso is a very backward, ignorant, and chaotic place, but do you know what the most advanced institutions here are?"

Hua Zhenxing: "As you raise this question, the answer is of course the International Hospital."

Fiso Port International Hospital was developed from a refugee tent hospital fifteen years ago. It has received funding from many international institutions and is now quite large. It has thousands of hospital beds and even forms a relatively independent safe area in the city, which is often overcrowded.

To say it is advanced means that it represents the highest level of facilities, including world-class research rooms, operating rooms, laboratories, intensive care units, and hundreds of high-end wards that are not inferior to those of private hospitals in developed countries. However, these conditions are not available to ordinary people. Most of the general wards and beds in the hospital are in poor condition, and the treatment and observation hall is overcrowded.

Rozchild nodded: "Yes, it not only has the most advanced medical equipment and various wards, but also the most advanced laboratories and research departments. It is large enough, has enough patients, and can see It reaches a variety of patients, so it has the best conditions for doing drug trials."

Hua Zhenxing frowned: "Are you conducting illegal drug experiments here?"

Rozchild shook his head and said: "It's not us, it's them. I didn't participate. As for whether it's illegal or not, foreign laws can't control the Port of Africa, and the laws of the country can't control the International Hospital, let alone they seem to There is no clear law in this regard.

The powerful people in this country will not interfere with the affairs of the International Hospital. As a tacit exchange, the International Hospital will also ensure their medical safety.

As for drug trials, there’s pretty much everything you can think of. At first, many institutions placed their laboratories here because it was convenient to conduct animal experiments. For example, monkeys here were easy to obtain, and there were no animal protection organizations to interfere... But later, many people realized another convenience .

Do you know the development process of a new drug? First, pharmacological and biochemical analysis, then animal testing, and finally clinical trials. Clinical trials are divided into phases one to four, and the cost is very, very high. If the research and development fails, all investment will be wasted.

But here, the cost is very low. First conduct pharmacological and biochemical analysis overseas, and then do the simplest animal testing here. The extent of animal testing sometimes depends on conscience..."

Hearing this, Hua Zhenxing interjected: "Will anyone skip the animal testing stage and go directly to clinical trials?"

Rozchild: "Yes, although there are not many such cases, I have found that it is best to test small doses on individual people first, and then continue if there are no serious reactions. But more often than not, animal testing is incomplete and the data If the accumulation and observation period is not enough, I will go directly to the clinic.

There are strict clinical standards. For example, in phase I trials, volunteers are usually healthy people. The volunteers in Phase II to IV trials are all patients with corresponding indications, that is, people with different diseases should take the medicine to treat that disease. The second phase trial also has a control group, that is, people with the same disease cannot take the drug and must either take a placebo or other marketed drugs. It is best to only take a placebo..."

Hua Zhenxing: "Just tell me the key points! I can go back and check the information on these."

Rozchild: "Drug trials require signing a responsibility agreement with volunteers to ensure that volunteers are fully informed and to provide adequate compensation to volunteers. But at Fisoport International Hospital, there are only patients and no volunteers. They are all just data. sample."

Hua Zhenxing took a breath: "Those people didn't actually know it? Not only were they not compensated, but they even spent their own money on drug trials for others?"

The Fiso Port International Hospital has a charitable nature, but it is not public in Kilian. It was first established by an international relief organization and accepts donations from organizations around the world. It also charges, and the charges are so expensive that few people can afford them, except for simple minor annoyances.

People who have no money but want to see a doctor can apply for assistance and need to fill out several forms. There are many illiterates here, and even more do not know foreign languages, so the forms are filled out by hospital staff, corresponding to different charity aid projects. You can spend no or less money if you get assistance from a certain project, but after all, some people spend their own money to see a doctor, at least part of it.

Rozchild nodded and said: "Actually, the most important thing is not these. The clinical trials here are not standardized. Sometimes, in order to obtain complete data in the shortest time and at the lowest cost, the first to third clinical phases are even mixed together. made."

Hua Zhenxing: "How to do this?"

Rozchild: "Direct administration and observation, starting from a small dose, some people are given the drug and some are not. Those with corresponding symptoms are given this drug, and those without corresponding symptoms are also given this drug... Sometimes you can get more Comprehensive data is difficult to obtain even through formal methods.”

Hua Zhenxing: "I didn't quite understand."

Rothchild: "For example, let's take contraindications and new indications. Usually volunteers in drug trials cannot have other underlying diseases. Drugs for digestion cannot be given to people with heart disease. "Knowing what the reaction will be will allow you to know now, or discover new conditions that the drug can treat."

Hua Zhenxing was speechless for a moment. After being silent for a long time, he asked, "Are all the doctors from the International Hospital involved?"

Rozchild quickly shook his head: "No, no, no, most doctors are not involved. They are here to treat patients. Their professional ethics do not allow them to do that, and they don't even know about it."

Hua Zhenxing: "How could you not know?" Unconsciously, his tone sounded like an interrogation.

Rozchild explained: "The situation in international hospitals is also very complicated. Doctors from different countries use drugs from multiple sources around the world, and it is normal to not understand many things.

In this most backward place in the world, the latest drugs developed from the most developed regions in the world can often be seen in hospitals. Some doctors also know that many drugs come from irregular sources, but they have no evidence to question them.

In this place, it would be nice to have medicine to treat illnesses. Basically, whatever medicine is available is used. Most doctors are still doing normal treatment and using medicines according to the instructions. After all, there are only a small number of people with problems, and even if they use the drugs with problems, most of them can still cure the disease..."

Having said this, he sighed again and said: "There are still many doctors who are not even qualified to question, or do not have the ability to question. For example, doctors from many backward countries are only told that there are the latest advanced drugs in the world. It was donated by a public welfare organization through special channels.”

Hua Zhenxing: "There is also a chain of contempt within the hospital, or it is called a chain of discrimination. For example, doctors from abroad look down on local doctors from Jili Country, and Dr. Luo, you should be at the top of this chain of discrimination, right?"

Luochaide did not answer the question, and Hua Zhenxing asked again: "You discovered these inside stories and collected evidence and materials in the hospital, so you were hunted down?"

Rozchild nodded and said: "Yes, I have collected a lot of first-hand original information, saved some samples, and mastered some people's secrets. I don't know that this matter has been exposed, but you called and said Jin Datou wanted to kill me, I knew it right then."

Hua Zhenxing: "What does this have to do with Jin Datou?"

Rozchild: “Drug trials have strict regulations, some of which are designed to protect volunteers. Failure to comply with these regulations may allow the trial to be completed faster and at a lower cost.

But on the other hand, it also has professional requirements, such as how to organize uninformed people to serve as volunteers, how to ensure that they are not testing another new drug while testing one new drug, how to follow up and observe... These all require local People help.

This is what Jin Datou does. The Datou Gang organizes physical examinations and medical treatment on their own territory, and even makes them take medicines that are said to have preventive effects on a regular basis. There are specialized people to make statistical observations. "

Hua Zhenxing suddenly remembered something: "Do you know Charles, the big man who shot at his accomplices yesterday to cover our escape? His aunt and two sisters were sick last year, and I asked you to help. The Big Head Gang organized People go to the hospital to be guinea pigs, why didn’t you help send them to the hospital as well?”

Rozchild smiled bitterly and said: "That's because she is really sick, and it is a fatal and severe infectious disease! The members of the Big Head Gang don't know the inside story. Only Jin Datou himself knows that he has the money."

Hua Zhenxing: "No wonder Jin Datou wants to kill you. The person who hired him is also determined to kill you."

There was a trace of ridicule on the corner of Rozchild's mouth: "There is only a reward of 30,000 meters in gold, and Jin Datou has people as spearmen. The interests involved are so huge that it might bankrupt several countries in several miles."

Hua Zhenxing: "Please explain it further."

Rothchild: "Actually, it's useless if Jin Datou knows about it. This is simply not something he can get. I'll give you a few examples. Which group has developed the latest drug, and how much does it cost? At what stage the trial has reached, with this information in the hands of professionals, they can basically judge whether the new drug can be launched on the market and its efficacy and profits after it is launched.

And knowing this, you know how the stock price will change, and knowing how the shares will change, you can operate in advance and use leverage to amplify. This is only one aspect. If this information falls to competitors, the value may be even greater. If some information is made public, it will cause scandals and cause huge losses to those pharmaceutical groups. "

Hua Zhenxing interjected: "Scandal? Scandal of illegal clinical trials?"

Rozchild sighed again, shook his head slightly and said: "In Mi Jian Country, not many people really care about the life and death of the people in Jili. The vast majority of people don't even know where Jili Country is, or even I didn’t know there was a country of several miles in the world.

But it involves capital interests. If operational flaws can be found and attacked, it will be a scandal in the capital market. For some large groups, if their stock prices only fall or rise by a few percentage points, do you know how much the market value will change? "

Hua Zhenxing: "According to this, how many pharmaceutical groups and how many types of drugs have you obtained illegal trial data?"

Rothchild: "Information is not equal to evidence. Even if you find someone doing this kind of thing, it is often useless. It is difficult to prove in law that it has anything to do with the person behind the scenes. What I want to master is the complete chain of evidence." , who is leading what project, what are their names, what identities do they have, and what experimental data have been produced.

Then check which companies have applied these data in documents required by law, and have applied for new drugs to be launched or are in the process of applying for new drugs to be launched. I have evidence of more than a dozen pharmaceutical groups and dozens of drugs. They are all the largest pharmaceutical groups in the world, some in Mijian Country and some in Luoba Continent.

I have an electronic backup, but electronic data alone is not enough. In some cases, original documents are also needed. I also got some samples that can be stored at room temperature. The samples and materials are usually locked in the office. Yesterday, there was an emergency, so I packed all the most important things in my backpack. "

Hua Zhenxing: "I can escort you to Miri Airport, but in this case, will it be safe for you to return to Mijian Country?"

Rozchild: "It's not that I'm unprepared, I won't go back to Mi Jian Country directly."

Hua Zhenxing: "What are you going to do?"

Rozchild avoided answering, raised his head and said, "You want to ask Jin Datou why he wanted to kill me, and I've already told you. Now it's your turn to tell me. The training you received is called Yangyuan Technique. Can you teach me it?" "

Hua Zhenxing summoned the "system" attentively and discovered to his surprise that the completion progress of "Mission One" had reached more than 90%. It seemed that what Dr. Luo told was basically the truth, but there were still some final situations that had not yet been clarified.