Back To The Age Of The '80s

"Well, the official news should come out soon." Li Zheng replied.

Guo Kezhen happened to walk nearby, and when he heard the voice, he turned his head and made eye contact with Li Zheng for a moment.

Li Zheng touched his nose and nodded to Guo Kezhen.

Guo Kezhen showed a complicated look on his face, and after nodding to Li Zheng, he continued the class.However, his next class became a lot more regular, and he no longer saw the enthusiasm when he just talked about gene editing technology.

The bell rang for the end of get out of class, and the students pushed me and pushed you, and walked to the door of the classroom hesitantly.

"Professor Guo, I'm really sorry for coming here without saying hello." Li Zheng showed a look of embarrassment on his face. He thought that there were so many students in a classroom, and the chances of him sitting in the corner were not high.

Guo Kezhen showed a polite smile on his face, "It's my honor that you can come to my class, but it seems that I am a little out of touch." He glanced at the densely packed notes on Li Zheng's open notebook. There was a hint of surprise.

"You're joking. In terms of genetics, I'm the only one who knows how to do it." Li Zheng paused, "I heard that you didn't fight for the host of the genome project?"

He was not good at beating around the bush, so he asked straightforwardly.

Hearing this, Guo Kezhen showed a look of annoyance on his face. If he didn't sign up, it meant that he showed weakness and gave up. There is no need for Li Zheng to remind him of this matter.

"Professor Li, this is my own business." Guo Kezhen said bluntly.

Li Zheng raised his eyebrows, said "oh", then said casually, "I have a lecture next Wednesday."

The words that obviously do not match the words behind the words are like thunder in Guo Kexin's ears.

Next Wednesday, isn't next Wednesday the first meeting of the Huaguo Genome Project preparatory group, at which the host of the Huaxia Genome Project will be selected. What does it mean that Li Zheng will have a lecture next Wednesday?

He didn't attend the preparatory meeting?

Which means...he passed up the opportunity to lead the genome project.

Look at Guo Kezhen looking at him like a madman.

Li Zheng smiled lightly, with a nice curve on the corner of his mouth.

"Professor Guo, people have self-knowledge. I still have some self-knowledge. In terms of genetics, I can only be your student. I will continue to participate in promoting the Huaguo Genome Project and international cooperation. We will cooperate in the future." Nice." He said, holding out his hand.

Guo Kezhen opened his mouth wide in a daze, and after a long time, he stretched out his hand and held it firmly with Li Zheng.

After returning from Yanda, Li Zheng contacted Li Zheng's laboratory in Xiangjiang.

In the past three years, Li Zheng has traveled to Hong Kong, Huajing, and Beijing. In addition to perfecting the technology of in vitro regeneration of organs, his other experiences have been devoted to the development of a human papillomavirus vaccine.

Many people may not know about human papillomavirus, but female compatriots in future generations should understand it as soon as they hear it.

This is a vaccine that can prevent cervical cancer. Many people in later generations call it the first vaccine that can prevent cancer. The hepatitis B vaccine is actually the first vaccine that can prevent cancer. Although it is clearly stated to prevent acute hepatitis when it is used in medicine, you have to admit that it has indeed greatly reduced the incidence of liver cancer.

At the end of the 80s and the beginning of the 90s, German biologist Howson had already published the view that HPV causes cancer. However, even though the Howson team discovered HPV16 and HPV18 and their carcinogenic mechanisms, pharmaceutical companies generally held a skeptical attitude towards this, and Howson’s paper After the publication, a series of various reports came one after another, all refuting the carcinogenicity of HPV.

After erlotinib entered the FDA approval process, Li Zheng met the German biologist at an international anti-tumor conference. He was trying to persuade international pharmaceutical companies to develop HPV virus vaccines.

GlaxoSmithKline and Merck, including those who later produced HPV vaccines, were not interested in HPV vaccines at this time.

"Even now, biology cannot fully explain the causal relationship between hepatitis B virus and liver cancer. He wants to repeat the miracle of hepatitis B virus, but he is too... anxious." Kent used an extremely euphemistic word.

Li Zheng raised his eyebrows, "But you have to admit that the hepatitis B vaccine has indeed made a great contribution in the history of mankind's fight against diseases."

Kent froze for a moment, then laughed, "Why, Li, are you interested in this HPV virus vaccine?"

Li Zheng smiled, "What if I said I'm interested."

Kent looked at Li Zheng for a long time, making sure that he did not lie again, shrugged, "Then maybe I can submit an evaluation report to the review team."

It is a very conservative statement to submit an evaluation report to the review team. With the speed of the Merck review team, it may not be possible to complete the review of a project in two or three years. It will be submitted to the review team for review.This already shows Kent's attitude towards this project.

The carcinogenicity of HPV will gradually be recognized by the world's biological circle after 1991. It took 16 years in my previous life to recognize the recognition of the biological circle, the attention of pharmaceutical companies, and the release of the drug by major research institutions.

Li Zheng also made some achievements in vaccinology in his previous life. The studio under his name has promoted the birth of domestic HPV virus vaccine.And before his sudden death, the HIV virus vaccine he presided over also showed good biological tolerance in biological tests, and the effectiveness reached more than 50.00%.In other words, if he is given another one or two years, the HIV virus that the people of the world have heard of may be able to end in his hands.

So Li Zheng found Howson and asked him for cooperation. For Howson at this moment, it is already very gratifying for someone willing to believe his point of view and invest a lot of money in vaccine research and development according to his point of view. .

What's more, Li Zheng didn't put forward any domineering requirements in the cooperation agreement. Hansoh can continue to persuade other pharmaceutical companies to develop vaccines while Li Zheng's laboratory is conducting drug research and development. This completely relieves Hansoh from any worries. .

So the German old man happily signed a cooperation agreement with Li Zheng.

Thus, Li Zheng's laboratory began a three-year anti-cancer vaccine research.

Up to now, the HPV virus vaccine of Zheng Li's laboratory can already protect against various high-risk HPV types, including types 16 and 18. 70% of cervical cancer is caused by two subtypes of HPV16 and HPV18. In other words, the HPV virus vaccine developed by Li Zheng's laboratory can theoretically prevent and treat 70% of cervical cancer.

It's just that the clinical practice of vaccines is always a great difficulty in the development of drugs, and Li Zheng has been very busy with it recently.He intends to use this as the first world-class drug clinical trial after the establishment of domestic drug clinical trial norms, but it is clear that the domestic risk assessment of this clinical drug is too high. Li Zheng talked with the drug control department several times and got All are answers that require further research.

"Li Zheng, Professor Howson hopes that the drug can enter the human clinical stage as soon as possible. What he means is that if Huaguo can't do it, he can find a way in Germany." Zheng Lingling said.

In three years, it is enough for a young lady who just graduated to transform into a qualified professional woman.

A drug patent can support a company, not to mention that Li Zheng's laboratory has multiple high-value drug patents, which is enough to make Zhenzhe Biotech a smooth sailing in the pharmaceutical industry, and it has good relations with major international pharmaceutical companies. Relationship.

The only thing lacking is a work that will let the world know about Zhenzhen, so Zheng Lingling is very concerned about this project.

Li Zheng rubbed his temples.

"Let me try again." Zhenzhe needs the recognition of the world, and so does Huaguo's pharmaceutical industry.

Zheng Lingling sighed, "Okay, you are the boss, but Li Zheng, Zhenzhen is also your industry, and the development of HPV has almost emptied all the patent money you have accumulated. The sooner you make a profit, the sooner you get back your money, I believe you I know this truth." Mr. Zheng now is not the little girl before, she will often make Li Zheng speechless.

"Okay okay, one last time. I promise it will be the last time."

**

On April 1990, 4, the Huaguo Human Genome Project was officially launched in the Great Hall of the People. Vice President of the Department of Biology of Yanda University, honorary president of the Huaguo Biogenetics Association, and Huaguo biologist Guo Kexin was appointed as the principal. host of the program.

There was thunderous applause in the auditorium.

"That kid Li Zheng really didn't come?" Zhao Depei clapped his eyes on the empty seat in the front row while applauding.

"He should be teaching at Jinjiang University now." Tian Lao said with a smile and turned his head to the side.

"A college of literature and history, what kind of courses should Li Zheng teach? Why, do they have the intention to move towards a comprehensive college?"

"Who knows. But Xiao Zhao, how much do you know about the project that Li Zheng is working on?" Tian Xiangjun had some rumors about the so-called small project Li Zheng was working on, but he was also skeptical about it.

"I don't know much about biology. If HPV virus and cervical cancer are really developed by him, the first anti-cancer vaccine in history, this title can still be worn if you want to wear it."

"Hausen's claim that HPV is carcinogenic is mixed internationally, and the clinical vaccine is still a cancer vaccine. This puts great pressure on the clinic. No wonder they refuse to control the drug."

"It's not like they don't want to. They want to achieve results but don't want to take risks. Lao Wang supports it, but there are too many people who oppose it in the department, and it's hard to support them alone."

"Officials are different from our research ones. They are safe and creative. They will choose to pursue the latter while ensuring the former."