Wang Xueba System
Chapter 644 Luo Hao's Research and Actions of the Beautiful Country
"When the telomere is exhausted, the cell will not die immediately, but if the cell continues to divide, it will damage the normal DNA fragments. When the damage accumulates to a certain extent, the cell will die. So how to make the telomere shorten quickly becomes a problem." I asked a question..." Luo Hao rubbed his chin, "There are two ways, one is to use external factors to influence, and the other is to use the characteristics of the cells themselves to shorten, such as forcing cancer cells to divide rapidly, right?"
"Eh? Rapid division?" Luo Hao was taken aback. "It seems possible! Cancer cells are a kind of mutated cells that divide rapidly. As long as the regeneration of telomeres can be inhibited, the previous problems can be solved."
"A part of the gene that constitutes the telomere is about 50 to 200 nucleotides, which cannot be completely replicated (lost) due to multiple cell divisions, so that the cell stops its function and no longer divides. Therefore, severely shortened telomeres are the result of cell aging. Signal. In cancer cells, cells with infinite replication cycles, the length of telomeres is retained after each cell division by a specific DNA polymerase-telomerase that can synthesize telomeres. Therefore, inhibiting telomeres Enzyme production in cancer cells directly inhibits telomere regeneration."
"Telomerase is a special structure at the end of chromosomes in eukaryotic cells." Luo Hao continued to look at the information in front of him, "Its synthesis is controlled by the tert gene. If we can control the expression of this gene, we can inhibit the activity of telomerase .”
"So the next research direction is determined, which is how to control the tert gene!" Luo Hao determined the next goal and began to study it.
"It is obviously unrealistic to directly replace genes that are not expressed, and it is easy to mutate genes again due to previous specific incentives."
"Therefore, only certain means can be used to continuously suppress genes in designated cells."
Thinking of this, Luo Hao took out his phone and made a call.
"Mr. Zhou, I need some liver cancer cells for experiments!" Luo Hao cut to the chase.
"Are you really going to study now?" Elder Zhou didn't mind Luo Hao calling him so late, but he was obviously taken aback, "Can you make it in such a short time?"
"It's not bad to try. It will take a few days before the preoperative examination. If it doesn't work, there is still time for resection!" Luo Hao said, "I need some liver cancer cells for experiments. cells for too long."
"Let me call you and contact the hospital to see if there is any remaining part of the previous test." Zhou Lao said, "Maybe Lao Luo has some ready-made in his body. Ask the doctor how to take it out."
Luo Hao grinned, is it okay now?
"Ask for me first." Luo Hao was a little bit unsure.
After hanging up the phone, Luo Hao sat on the chair and meditated while waiting for Mr. Zhou's reply.
Soon, Elder Zhou's reply came.
"I'll send you to Fuxing Academy in a while!"
"Can't it be Xianga's?" Luo Hao asked tentatively.
"The rest of the test before." Zhou Lao said, "It was cut from the tumor for you. Fortunately, you said it early, otherwise the hospital should have disposed of it."
"Okay, thank you, Mr. Zhou!"
Luo Hao waited quietly in the laboratory.
............
On the other side, under the urging of the beautiful country and the rose country, the country of romance finally gave an answer: agree to support the proposals of the two countries, but the two countries need to make compensation for the risks that the country of romance will take in the future!
"Fuck!" Bai Deng scolded, "This Bell is really greedy. What good does Xia Guo develop for him? He still wants us to make up for it?"
"Bell is too greedy. The Romance Kingdom is just eating the old man. If you don't be greedy now, how will they live in the future?" Rishi sneered, although it sounded like he was explaining for Bell, it was not difficult to hear from the tone , his dissatisfaction with the kingdom of romance.
"Compensation can be given, but not too much. At worst, let Xia Guo develop and see who will regret it first!" Bai Deng snorted and took the lead in expressing his opinion.
"This matter needs to be finalized quickly, and we have to convince the Polar Bear Country later. The election of the council will start soon." Lixi also acquiesced in this matter with some helplessness.
Under the deliberations of the leaders of the three countries, an agreement was quickly reached.
Pretty Country agrees to increase Romantic Country's right to use the International Space Station, at the expense of Pretty Country and Rose Country.
After reaching an agreement, Biden contacted the polar bear country as a representative of this negotiation.
"Vladimir, my old friend, it's been a long time!" Bai Deng had a warm smile on his face, completely unable to see the tit-for-tat between the two countries.
"Why does Mr. Bai Deng have time today?" Vladimir also had a smile on his face, but compared to Bai Deng, the smile was a little blunt.
"Today, on behalf of the Country of Beauty, the Country of Roses, and the Country of Romance, I propose cooperation to the Country of Polar Bears." Bai Deng laughed, "Our three countries want to exclude Country Xia from the general election of the council members. I don't know Is Mr. Radimir interested?"
"Xia Country and our Polar Bear Country have always been friendly neighbors. Our Polar Bear Country doesn't treat friends like this." Vladimir sneered, obviously not interested in Biden's proposal at all.
"Don't worry, I have a suggestion, Mr. Vladimir, why don't you listen to it first?" Seeing that the other party was silent, Bai Deng continued, "We can help the Polar Bear Country choose a country you selected as a new council member. , to replace the status of the Xia Kingdom, so that the situation of the Polar Bear Country will not be affected in any way, and even the international status of the Polar Bear Country can be improved!"
"After all, Xia Guo doesn't completely obey the orders of the Polar Bear Kingdom, do you think so?" Bai Deng looked at Vladimir in the video call and showed a smug smile.
"Can such a good thing happen?" Vladimir sneered, obviously not believing it.
"Of course, the elected country can't be too powerful, anyway, you don't want him to be out of your control, do you?" Bai Deng still smiled, "Xia Guo has a good saying, how can others sleep soundly on the side of the couch? Xia Guo has been developing too fast recently, you don't want to have a powerful country next to you, do you?"
"Tell me in detail." Finally, Vladimir stopped refusing immediately, as if he had a slight interest.
"The conditions mentioned before are already very good, right?" Bai Deng showed a smug smile on his face, "This is a rare opportunity. I can guarantee that the polar bear country will not have such a good opportunity again!"
"Eh? Rapid division?" Luo Hao was taken aback. "It seems possible! Cancer cells are a kind of mutated cells that divide rapidly. As long as the regeneration of telomeres can be inhibited, the previous problems can be solved."
"A part of the gene that constitutes the telomere is about 50 to 200 nucleotides, which cannot be completely replicated (lost) due to multiple cell divisions, so that the cell stops its function and no longer divides. Therefore, severely shortened telomeres are the result of cell aging. Signal. In cancer cells, cells with infinite replication cycles, the length of telomeres is retained after each cell division by a specific DNA polymerase-telomerase that can synthesize telomeres. Therefore, inhibiting telomeres Enzyme production in cancer cells directly inhibits telomere regeneration."
"Telomerase is a special structure at the end of chromosomes in eukaryotic cells." Luo Hao continued to look at the information in front of him, "Its synthesis is controlled by the tert gene. If we can control the expression of this gene, we can inhibit the activity of telomerase .”
"So the next research direction is determined, which is how to control the tert gene!" Luo Hao determined the next goal and began to study it.
"It is obviously unrealistic to directly replace genes that are not expressed, and it is easy to mutate genes again due to previous specific incentives."
"Therefore, only certain means can be used to continuously suppress genes in designated cells."
Thinking of this, Luo Hao took out his phone and made a call.
"Mr. Zhou, I need some liver cancer cells for experiments!" Luo Hao cut to the chase.
"Are you really going to study now?" Elder Zhou didn't mind Luo Hao calling him so late, but he was obviously taken aback, "Can you make it in such a short time?"
"It's not bad to try. It will take a few days before the preoperative examination. If it doesn't work, there is still time for resection!" Luo Hao said, "I need some liver cancer cells for experiments. cells for too long."
"Let me call you and contact the hospital to see if there is any remaining part of the previous test." Zhou Lao said, "Maybe Lao Luo has some ready-made in his body. Ask the doctor how to take it out."
Luo Hao grinned, is it okay now?
"Ask for me first." Luo Hao was a little bit unsure.
After hanging up the phone, Luo Hao sat on the chair and meditated while waiting for Mr. Zhou's reply.
Soon, Elder Zhou's reply came.
"I'll send you to Fuxing Academy in a while!"
"Can't it be Xianga's?" Luo Hao asked tentatively.
"The rest of the test before." Zhou Lao said, "It was cut from the tumor for you. Fortunately, you said it early, otherwise the hospital should have disposed of it."
"Okay, thank you, Mr. Zhou!"
Luo Hao waited quietly in the laboratory.
............
On the other side, under the urging of the beautiful country and the rose country, the country of romance finally gave an answer: agree to support the proposals of the two countries, but the two countries need to make compensation for the risks that the country of romance will take in the future!
"Fuck!" Bai Deng scolded, "This Bell is really greedy. What good does Xia Guo develop for him? He still wants us to make up for it?"
"Bell is too greedy. The Romance Kingdom is just eating the old man. If you don't be greedy now, how will they live in the future?" Rishi sneered, although it sounded like he was explaining for Bell, it was not difficult to hear from the tone , his dissatisfaction with the kingdom of romance.
"Compensation can be given, but not too much. At worst, let Xia Guo develop and see who will regret it first!" Bai Deng snorted and took the lead in expressing his opinion.
"This matter needs to be finalized quickly, and we have to convince the Polar Bear Country later. The election of the council will start soon." Lixi also acquiesced in this matter with some helplessness.
Under the deliberations of the leaders of the three countries, an agreement was quickly reached.
Pretty Country agrees to increase Romantic Country's right to use the International Space Station, at the expense of Pretty Country and Rose Country.
After reaching an agreement, Biden contacted the polar bear country as a representative of this negotiation.
"Vladimir, my old friend, it's been a long time!" Bai Deng had a warm smile on his face, completely unable to see the tit-for-tat between the two countries.
"Why does Mr. Bai Deng have time today?" Vladimir also had a smile on his face, but compared to Bai Deng, the smile was a little blunt.
"Today, on behalf of the Country of Beauty, the Country of Roses, and the Country of Romance, I propose cooperation to the Country of Polar Bears." Bai Deng laughed, "Our three countries want to exclude Country Xia from the general election of the council members. I don't know Is Mr. Radimir interested?"
"Xia Country and our Polar Bear Country have always been friendly neighbors. Our Polar Bear Country doesn't treat friends like this." Vladimir sneered, obviously not interested in Biden's proposal at all.
"Don't worry, I have a suggestion, Mr. Vladimir, why don't you listen to it first?" Seeing that the other party was silent, Bai Deng continued, "We can help the Polar Bear Country choose a country you selected as a new council member. , to replace the status of the Xia Kingdom, so that the situation of the Polar Bear Country will not be affected in any way, and even the international status of the Polar Bear Country can be improved!"
"After all, Xia Guo doesn't completely obey the orders of the Polar Bear Kingdom, do you think so?" Bai Deng looked at Vladimir in the video call and showed a smug smile.
"Can such a good thing happen?" Vladimir sneered, obviously not believing it.
"Of course, the elected country can't be too powerful, anyway, you don't want him to be out of your control, do you?" Bai Deng still smiled, "Xia Guo has a good saying, how can others sleep soundly on the side of the couch? Xia Guo has been developing too fast recently, you don't want to have a powerful country next to you, do you?"
"Tell me in detail." Finally, Vladimir stopped refusing immediately, as if he had a slight interest.
"The conditions mentioned before are already very good, right?" Bai Deng showed a smug smile on his face, "This is a rare opportunity. I can guarantee that the polar bear country will not have such a good opportunity again!"
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