Wang Xueba System

Chapter 643 The Role of Telomeres

Luo Hao shook his head, without further explanation, he entrusted Wang Gang with a few more words, and took Huang Xi away from the First Hospital of the Beijing Military Region.

"Xiaohao, since the operation can be performed, Grandpa Luo should be fine, right?" Huang Xi tried to comfort him.

"Not necessarily." Luo Hao shook his head slightly, "Cancer is different from other diseases. As long as you get it once, even if you are cured this time, the probability of recurrence is very high, and most people, as long as they have a recurrence, will usually recover. It can't be saved."

"Besides, the old man is not young, it's hard to say whether he can survive this operation." Luo Hao sighed, and took Huang Xi into the car.

"Then what are you going to do?" Huang Xi asked.

"Cancer happens to be a little related to the project I'm researching. Originally, I started that project because of the old man. Now it seems that I have to speed up." Luo Hao frowned, as if he had made up his mind.

Not long after Luo Hao left, several heads of state, or representatives of the heads of state, came to the First Hospital of the Beijing Military Region to visit Luo Zhenguo.

"Lao Luo, you can rest easy and recuperate!" Zhou Lao said, "You don't have to worry about work."

"En." Luo Zhenguo agreed, and turned his eyes to look around.

"Don't look for it, Luo Hao has already arrived, he just left not long ago." Elder Zhou said, "He was the first one to come!"

Luo Zhenguo was taken aback, and looked at Wang Gang who was at the side.

"Mr. Luo Hao did come. Later, he said that he would find a solution, and then told me to contact him at any time if there was anything to do, and then left." Seeing this, Wang Gang said hastily.

"What can he think of?" Mr. Zhou was taken aback, "The only medical-related projects he has been in contact with before are only one biological valve project."

"It's okay, if he's busy, let him be busy!" Luo Zhenguo said, he was already content with Luo Hao being able to visit him.

"I'll ask him later." Elder Zhou was obviously very curious about Luo Hao's words, and also a little angry.After all, Luo Zhenguo is so old and still suffers from this kind of disease. As a junior, Luo Hao should spend more time with him.

"Okay, Lao Luo, take a good rest, we are waiting for you to recover." Zhou Lao smiled, "Your brothers are waiting for you!"

"Okay!" Luo Zhenguo agreed with a smile on his face.

Wang Gang replaced Luo Zhenguo to send Zhou Lao and others out of the ward.

"Lao Luo doesn't know what disease he has?" Zhou Lao looked at Wang Gang.

"I don't know, I asked the doctor to tell him it's common hepatitis." Wang Gang replied, "But it shouldn't be hidden for too long. It's not like the commander has never seen this kind of disease."

"Luo Hao told you at the time that he was going to figure out a solution? He didn't say anything else?" Elder Zhou asked again.

"Well, I didn't say anything else." Wang Gang was also a little strange, "I haven't heard that he has any achievements in medicine?"

"I'm afraid he is going to learn now!" Mr. Zhou took a deep breath, "Many of the projects he studied before are all learned now. If this kid doesn't force him, he will always want to be lazy in a hurry. I guess No one will be found again!"

"Learning now?" Wang Gang grinned, "But this time it's different, this is a terminal illness, except for surgery that can effectively prolong life, other treatments are basically palliative, not the root cause, even with surgery there is a possibility of recurrence. "

"He wants to try, let him try, what if it works?" Mr. Zhou shook his head, "Okay, don't send it away, take good care of Lao Luo, and call anytime if you have anything!"

............

Renaissance Academy.

Luo Hao had already returned to Fuxing Academy at this time, and after sending Huang Xi back to the dormitory, Luo Hao arrived at the most advanced laboratory in the entire Fuxing Academy without stopping.

"Cancer cells were noticed in previous research on ways to extend human lifespan."

"The biggest difference between cancer cells and normal cells is that their division and proliferation are uncontrolled, and they will proliferate a lot of useless tissues to form tumors in a very short period of time."

"The reason for this is that the activity of telomerase in cancer cells is much higher than in normal cells, which increases the upper limit of the number of times the cells can divide."

"On the other hand, it is because the proto-oncogenes in cancer cells are activated, while the activity of tumor suppressor genes is reduced, resulting in uncontrolled cell proliferation."

"According to previous studies, the proto-oncogene can affect the activity of telomerase. If the proto-oncogene can be controlled to be slightly higher than the low expression state, it should be able to increase the activity of telomerase and increase the number of cell divisions in a disguised form." upper limit."

"Now, what the old man has is cancer, that is to say, the proto-oncogene is in a state of high expression, and the tumor suppressor gene is inactive. If we can adjust the expression of the two genes in the cell species, we can cure the cancer!"

Luo Hao recalled his previous deduction, and after confirming that there was no logical error, he began to study it.

In the past, this project and the artificial intelligence project were alternately researched. Now, Luo Hao does not intend to waste any more time. He has to hurry up and research a cure for cancer!

In the eyes of ordinary people, this is completely an impossible task!

What's more, Luo Hao needs to research his own treatment method before Luo Zhenguo's treatment plan is finalized, otherwise Luo Zhenguo will have to undergo surgery. That being said, the burden is still too great!

Luo Hao opened a document on the computer.

This is a resource that introduces telomeres and knowledge about them.

To treat cancer, first of all, it is necessary to inhibit the division of cancer cells. Only in this way can the cancer cells die on their own due to life expectancy without using any other anticancer drugs.

One of the most critical points is the telomere.

Telomere is a short DNA-protein complex that exists at the end of eukaryotic linear chromosomes. Telomere short repeats and telomere binding proteins form a special "cap" structure, which is used to maintain the integrity and control of chromosomes cell division cycle.Telomeres, centromeres and origins of replication are the three major elements of chromosome integrity and stability.

The length of telomere reflects the history and potential of cell replication, and is called the "mitotic clock" of cell lifespan.

"Telomeres can ensure the stability of chromosomes, and can also limit the cycle and number of cell divisions. As long as the telomeres in cancer cells are accelerated and shortened, and no longer grow, the number of divisions of cancer cells can be limited, and even , if the speed of telomere shortening is increased, the stability of the chromosomes of cancer cells will be severely reduced, and the death of cancer cells will be promoted!"

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