Rule department scholar
Page 428
"It's a big deal!"
Uncle Zhong nodded responsibly, "Okay! Don't worry, Academician Zhao, as long as you are from the Faculty of Science, even a fly will not fly in!"
After doing this thing, Zhao Yi was really clean for a few days, but only three days later someone came again.
Qian Zhijin!
"Zhao Yi, Zhao Yi!"
Under the staring eyes of several people in the research institute, Qian Zhijin waved hello bravely, and then said with a bitter face, "I have no choice but to be forced to come here by some old men."
"But what's the relationship between us?"
"Don't worry, I won't say anything, just sit here for a while, and go out when it's about time."
Qian Zhijin felt that he did a good job, but he was kicked out by Zhao Yi, "We are doing a secret experiment."
"Huh? Really keep it secret?"
"of course."
Zhao Yi nodded seriously.
Qian Zhijin noticed carefully that Yan Xuelin and Han Hui were still in the laboratory, and they all looked serious.
"Ok."
He left helplessly.
When walking out of the Biomedical Research Institute, Qian Zhijin still felt a little strange. People from the Faculty of Science kept saying that the "secret experiment" at the door was an excuse, but how could it really be kept secret after entering?
Of course keep it a secret!
The research on 2CV-Bing hydrogen molecule itself is confidential, and other laboratories do not talk about this substance.
Now Zhao Yi's group has made a new discovery. They have just extracted the small protein substance secreted by mutant E. coli and used it to conduct anti-HIV experiments. The results are somewhat unexpected.
Small protein substances can not play the role of 2CV-Bing hydrogen molecule, but combined with HIV.
They are analyzing and discussing the combination.
Han Hui thinks it is a common 'attachment' effect, "This small protein substance is similar to 2CV-Bing hydrogen molecules, but it can't weaken the ability of HIV to invade cells. Maybe it just attaches to the surface of the virus and binds to a certain protein. together."
She described it as 'a virus with dust on it'.
While dust can make viruses look weird, it doesn't do much good.
Yan Xuelin also participated in the discussion, and he thinks it is worth researching, "We can analyze its composition carefully to see how different it is from 2CV-Bing hydrogen molecules."
"From the research on it, it may be possible to find a way to mass-produce 2CV-Bing hydrogen molecular drugs."
Li Mingdao, "I think it may not be possible to find a method for drug development, but it may have other effects."
Everyone else looked over.
Li Ming analyzed, "First of all, it can act on the bacillus antibody and make the antibody lose its effect. Conversely, it is equivalent to weakening the immune function, which can be used to make drugs that lower immunity."
"Yup!"
"Makes sense!"
"A new small protein molecule may have other effects, you are right!"
Everyone else nodded.
There are many types of drugs, and some drugs are used to reduce immunity. The main function of drugs to reduce immunity is to reduce the body's rejection of foreign objects.
For example, heart stents.
The stent placed in the blood vessel is definitely a 'foreign object', which will be rejected by the human immune system. Patients who have undergone heart stent surgery need to take long-term drugs to reduce immunity to reduce the rejection of the immune system.
New small protein substances can bind to Bacillus antibodies, and may be used to make some special drugs.
"I think……"
Zhao Yi suddenly opened his mouth, and other people looked over, and he continued, "I think, maybe we all underestimated the role of this small protein molecule." He was talking about us, but he was actually talking about other people.
"How to say?" Yan Xuelin asked with interest.
Zhao Yi was a little agitated, but still took a deep breath, and said seriously, "This small protein molecule can bind to HIV, maybe it's not just attached, maybe it will have other effects?"
"For example, like an antibody, to mark the virus?"
After he finished speaking, he looked at the others.
Yan Xuelin's eyes widened suddenly, and Han Hui and Li Ming opened their mouths in surprise, "Impossible!"
"impossible!"
"It is an external substance secreted by E. coli, and it cannot function as an antibody!"
Several people shook their heads while talking.
Zhao Yi continued, "What if it binds to the bacillus antibody? The bacillus antibody is a marker bacillus. This small protein molecule is attached to the surface of HIV, and then combined with the bacillus antibody, the immune system may be able to treat HIV..."
He speaks very slowly.
Han Hui immediately reacted, and immediately continued, "...recognized as a bacillus? Then killed by the immune system?"
"—!!"
Several people in the laboratory all stared wide-eyed, they finally understood why Zhao Yi was so excited.When they heard this analysis, their brains buzzed, as if they were about to explode.
HIV can be recognized by the human immune system, whether it is recognized as HIV or a certain type of bacillus, the meaning is the same, and it will definitely be eliminated by the phagocytes of the immune system.
what does this mean?
Yan Xuelin said with certainty, "This also means that we have solved AIDS!"
"That's right!"
"In the future, AIDS will be cured by drugs!"
Ai Lixin stood on the edge and did not speak. When several people were discussing excitedly, he suddenly rushed to the door, opened the door and looked around.
Dai Tianqing came over and asked, "Old Ai, it is said that you have made a new discovery? What discovery?"
"No comment!"
Ai Lixin yelled at the top of his voice, and closed the door of the laboratory with a bang, almost hitting Dai Tianqing's face.
"Crack!"
lock it!
Dai Tianqing stood at the door in a daze, raised his head to knock on the door, then put it down, and said depressedly, "What's going on? What are you doing? We're all doing research together, why don't you have anything to say! I'm afraid I'll come to find out about the military situation! "
"About your research?"
"Our group is about to make big achievements!"
Dai Tianqing thought that he was in a much better mood, and wandered back to the laboratory whistling.
……
"Study this!"
"Just study this!"
"I will immediately apply to my superiors for secrecy. Before the effect is determined, the entire research institute is only allowed to enter, no need to exit!"
Yan Xuelin made a quick decision.
The last time I submitted a report to the superior to apply for confidential research, it was because of the discovery of 2CV-Bing hydrogen molecule, which can weaken HIV, but after all, it only weakens rather than eliminates it.
In addition, the effect of 2CV-Bing hydrogen molecules has not been officially confirmed, but theoretically speaking, the effect will not be very surprising, because the human body will decompose 2CV-Bing hydrogen molecules, and 2CV-Bing hydrogen molecules are not targeted proteins , and only when it meets HIV in the blood can it produce the effect of weakening HIV, that is to say, it must be injected in large doses, which may cause some other side effects.
For example, increasing the burden on the kidneys.
Now the newly discovered small protein molecules are different, because they are mutated by Escherichia coli and secreted against bacilli antibodies. They may not be recognized and decomposed by the human body, but will also stick to the surface of HIV and combine with bacilli antibodies. AIDS The virus is tantamount to being marked incidentally.
The new small protein molecules plus bacillus antibodies constitute the 'HIV antibodies'.
"If this is really the case, we will have completely solved AIDS!" Yan Xuelin felt very excited when he said this.
That's AIDS!
HIV is one of the most harmful diseases to human beings, and even one of them is excluded, because there are too many people suffering from AIDS, and there is no cure for it.
When you are infected with HIV and blocking drugs are ineffective, you can only use drugs and treatment to delay the time of onset and death.
Everyone in the lab was excited.
Yan Xuelin was agitated for a long time, and finally regained consciousness, and immediately said, "Calm down, everyone, calm down!"
"What Zhao Yi said is not necessarily correct, and we don't have 100% hope!"
"That's just a possibility!"
"Correct!"
"It's just possible..."
When thinking of the word 'possible', Yan Xuelin suddenly became excited again.
Li Ming, Ai Lixin, and Han Hui were the same, they didn't know what to say, they just sat there in a daze.
Only Zhao Yi and Zhang Wei could keep calm in the lab.
Because Zhao Yi knew the result, he didn't have "uncertainty" or "possibility" in his heart, but was very sure of what he said, and it would be fine to just wait after getting excited.
Zhang Wei trusts Zhao Yi very much. She is also relatively young and knows that solving AIDS is a super big achievement, but her mentality is definitely calmer than that of "old people" such as Ai Lixin and Han Hui.
The laboratory fell silent for a while.
Instead, Zhang Wei stood up to 'preside over the overall situation' and said, "Director Yan, we are just waiting now, right? But we can also make some preparations, there will definitely be a leader coming soon."
"Yes, prepare! Prepare!"
Yan Xuelin immediately came to his senses and knew what to do. He said, "Zhao Yi's discovery, right? This is your laboratory. If you need any help, just let me know."
"Let's sort out the information together!"
"Let's sort out the records of the experiment process..."
The laboratory suddenly became busy.
……
Institute of Biomedicine.
Inside the main entrance.
When Yan Xuelin announced that he would apply for secrecy, he immediately called the guard, Uncle Zhong, and asked him to close the main entrance immediately, and all personnel in the institute were only allowed to enter and not to exit.
Uncle Zhong closed the front door.
Dai Tianqing strolled around the laboratory, and then went out to eat with Chen Zhigang. On the first floor, he found that the door was closed, and several people were discussing, "Why is the door closed?"
"Can't get out."
"What's the matter? Don't give up? What should we do when we eat? Old Zhong! Old Zhong!"
Uncle Zhong stood outside the main entrance and yelled inside to explain, "It was Director Yan who said that you are only allowed to enter and not to exit!"
Dai Tianqing walked over a few steps, and after asking, he found out that it was Yan Xuelin who applied for secrecy. He immediately remembered Ai Lixin's reaction, and asked strangely, "Is there really any big discovery?"
He quickly rushed to the second floor, went to the laboratory where Zhao Yi's group was located, and knocked hard on the door, "Open the door! I'm Dai Tianqing!"
Chen Zhigang followed.
The door was opened to reveal a gap, Zhao Yi poked his head out from inside, and asked with a smile on his face, "It's Old Dai! Brother Dai."
"Haha, Zhao Yi, let's go in, we are all doing research together."
Dai Tianqing said softly.
Zhao Yi frowned and explained, "However, Director Yan said that only members of our group or those who know the news can come in." Then he frowned and asked with a smile, "Do you want to come to our group?"
"Okay!"
Dai Tianqing immediately nodded vigorously.
Chen Zhigang next to him said dissatisfiedly, "No, we are a team..."
Before he could finish speaking, Zhao Yi said regretfully, "Unfortunately, the crowd is full, so there is no way."
He withdrew his head and slammed the door shut.
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