Blooming America

What is Paramecium?

This is a small, cylindrical protozoan. It consists of only one cell. It is a unicellular animal and is hermaphroditic. .

The most common is Paramecium cerevisiae. The body length is only 180 to 280 microns. It and the amoeba have the shortest life span, calculated in hours, and the life span is about one day and night. It is called Paramecium because its body shape looks like an upside-down straw sole from a plane angle.

Hayflick, at this time, is studying Paramecium.

The repair protein of damaged tissue is terrible.

This repair protein, which has lost the most basic recognition ability, has become a virus-like parasite-the properties of this protein are so similar to viruses that Hayflick had to think so.

Of course, this repair protein is not exactly the same as a virus. Although this repair protein is a protein, it does not have the genetic material of rna or dna, so it cannot be infected. Although it will "infect cells", it will not expand the disease. .

Although there are lives that use protein as genetic material, this is not a repair protein.

In Hayflick's view, "Mr. Smith"'s alternation protein is more like a protein life, but although the other party can synthesize various substances, it has no way to synthesize and cannot "reproduce", so it is also called no. Shang is a form of life.

Under the electron microscope, Hayflick caught every move of the paramecium.

The whole body of Paramecium is composed of a single cell. There are a pair of formed nuclei in the body, namely the nutrient nucleus and the reproductive nucleus. The former is also called the macronucleus and the latter is also called the micronucleus. Although this kind of life is a single cell, it also carries out sexual reproduction. . During reproduction, small nuclei divide and large nuclei disappear. Small nuclei gradually grow to form new large and small nuclei, so they are called eukaryotes.

The surface of its body is covered with a layer of membrane, in addition to maintaining the body shape of the paramecium, it is also responsible for internal and external gas exchange, absorption of oxygen in the water, and emission of carbon dioxide.

There are nearly ten thousand cilia growing densely on the membrane, which rotates in the water by the stroke of the cilia.

In Hayflick's view, Paramecium is a very good experimental subject.

It is obviously impossible for Mr. Smith to provide his own cells, and even if the cells of other people are useful, it is impossible to continue to provide them.

If you want to carry out "mass production", the first thing you need is a convenient raw material.

At this time, Smith thought of Escherichia coli, some other bacterial life, and so on.

But until the end of the experiment, Smith discovered that so far, only Paramecium meets his requirements. //

Compared with Paramecium, bacteria have no mature nucleus, endoplasmic reticulum, Golgi apparatus, mitochondria, lysosomes, centrosomes, and secondary vesicles, which are not complete structures that can be used for testing.

Although the repair protein requires cells, the repair protein does not require the nucleus of the cell itself.

On the paramecium, this characteristic is expressed vividly.

There is a small recessed groove on one side of the paramecium, called "mouth groove", which is equivalent to the "mouth" of the paramecium.

When the dense and long cilia in the sulcus swing, the bacteria and organic debris in the water can be placed into the sulcus as food, and the side without the sulcus will rotate in a circle with the edge as the vertex, and the larger debris is discharged by the cilia , And then enter the body of Paramecium to form food bubbles for its slow digestion and absorption.

Food residues are discharged from the anus.

Paramecium belongs to the most primitive and lowest protozoa in the animal kingdom.

Of course, don't look at this thing as small, but it's not easy.

It likes to live in ditches or ponds with a lot of organic matter and feed on bacteria and algae. It is estimated that a paramecium can form about 60 food bubbles per hour. Each food bubble contains about 30 bacteria. Therefore, a paramecium can swallow approximately one bacteria per day, which has a certain purification effect on sewage.

But now, the mouth of this Paramecium has disappeared and the surface has undergone drastic changes.

Ok……

Hayflick suddenly thought of "Resident Evil."

When I was buying an nrbus game console for my son, I was attracted by that interesting t virus, and I played that game for a long time.

For Paramecium, the repair protein is its "t virus".

At this time, the repair protein has completely replaced the "brain" of the paramecium, which is the nucleus of the paramecium.

At this time, the repair protein is manipulating this puppet, doing what it wants to do-synthesis.

Although the protein structure has been damaged, the part related to synthesis remains intact.

The protein reversely synthesizes messenger RNA, and then these RNAs use the body cells of the paramecium itself to carry out the synthesis of the organism.

After the paramecium has completely dried up, the repair protein will look for other puppets, and continue to synthesize organic matter until the other paramecium also dies, and then this process will continue until the repair protein completely collapses. This process takes about three days.

Hayflick even conducted experiments. Although this repair protein will not be affected by other repair proteins, it will still be "harmonized" when it encounters altered proteins, even when it is encountered by human white blood cells. , Will also be treated as a foreign substance and be destroyed. This has already shown that this kind of living body already exists in two ways with the original repair protein.

For this reason, Hayflick named it the s protein.

The s protein is only because of the existence of t virus, because s comes in front of t. In Hayflick’s view, this thing is the paramecium t virus, that is, it lacks infectivity. If this s protein can also be contagious...it really is the t-virus of the Paramecium kingdom...

"It would be great if I could self-replicate. In this case, I don't have to continue to find a way to synthesize. I can get new proteins directly and continuously..."

Hayflick really wants to make it reproducible...

However, in Hayflick’s view, this s-protein is not perfect because it will always synthesize organic matter, no matter what it is, organic matter or silicide, as long as it is of the same kind, This thing will continue to synthesize it according to a certain structure, and finally get the product, but this kind of "hodge-podge" is completely useless in Hayflick's view.

But this is not impossible.

As long as you can synthesize this protein in large quantities, and then throw these paramecium worms into a solvent with only selected materials and let them be parasitic, you can synthesize enough products...Of course, among them, paramecium The corpse of the worm will also become a magazine, but it can basically ensure sufficient purity, and the rest can be purified as long as it is done...···

"so perfect!"

Hayflick was impressed by this idea.

Once this idea is realized, it will inevitably usher in a sensation in the field of science and materials science!

As long as you find out the rules of synthesis, and then put the corresponding semi-finished products into it, and let these repair proteins undergo brainless synthesis, the next work can be much simpler. Maybe humans can still get unexpected things, such as some emerging organic products, or more simply things that humans can’t synthesize now...

In this case, everything will change drastically, and the whole world will shake!

As for the synthesis of this s protein, Hayflick already has an idea, and the previous research results of another damaged protein are not without merit. The synthetic material is more troublesome, far from the current one. This kind of convenience, so Hayflick is very optimistic that he can find a synthetic method in the laboratory in more than half a year, and research on industrial production will probably only take five to five. Only ten years.

"If a sufficient amount of s protein enters the human body, what will happen?"

At this moment, Hayflick suddenly had this idea.

The amount of s protein I got at the beginning was very small, and there was no response when entering the human body, but once I could produce a large amount of s protein, what would happen to this protein at that time?

It’s just Hayflick’s ethics and professional ethics that didn’t allow Hayflick to do such a human experiment. Hayflick’s idea just flashed through his mind. He absolutely didn’t Will want to do human trials.

"Although... the human body cannot, but if it is a dead corpse, is it possible? As long as the cells of the whole body are not dead, as long as the s protein can be parasitized, then next, Will this protein drive the human body? Or will there be any interesting changes?"

Although Hayflick was very ethical, at this time, he still couldn't help but want to fantasize in his head.

"If...it is parasitic to the nervous system, is there any unexpected situation?"

Damn it! Why do I always think about the human body, the human body!

Hayflick suddenly wanted to slap himself~www.wuxiaspot.com~ Now I'm experimenting with mice, isn't it all right? !

The mouse is a very convenient tool in the laboratory, and there is no psychological pressure to kill it.

And because of its small size, the amount of s-protein that needs to be consumed is not a lot, so you can do the experiment now!

Reluctantly glanced at the paramecium that had been struggling, Hayflick, who was "empathetic". At this time, he was already preparing to experiment with mice.

Because of the strange-thought at the beginning, Hayflick at this time could no longer bear it.

He is eager for knowledge, eager to know what will happen next...

Three shifts...

It's all vague...