Prussian Blue was truly born.

When Da Vinci brought this tube of paint, Heidi was flipping through a new book borrowed from the Florence Academy.

When she looked up, she didn't see the painter with dirty hands, but the tube of paint in his hand.

This is pure Prussian blue without any impurities after screening and filtering.

It is so deep and gorgeous, reminiscent of the unfathomable deep sea, and the tea rose known as the blue enchantress.

Any language to describe such a color seems a little pale and powerless.

"You did it—" She felt that she had regained her spirits, and she even wanted to jump up from the bed to hug him at this moment: "It's exactly the same as I remember!"

Da Vinci laughed and handed the tube of paint to Heidi.

"Get well soon." He stared at her and said, "I'm still waiting for your reminder—the painting for the new order has been delayed for at least two weeks."

Heidi laughed dumbfounded, and gave a long answer.

By the time she finally regained her strength and began to walk outside the courtyard, Florence had already entered spring.

The sun is like a warm embrace, and it feels warm even when it finds someone.

The citrus on the roadside began to bloom and bear fruit, and it smelled green and astringent.

Because Da Vinci received a new order last year, now he needs to help the lord complete various researches while finishing the previous oil painting.

He and Heidi wrote a "Florence Development Forecast", and also noted the relevant tables and assessments-of course, Heidi taught him these modern ways of thinking.

The first step is to develop the economy in an all-round way.

Be it science and technology or the military, these things themselves need to be supported by strong economic strength.

In addition to the well-developed art industry in Florence, handmade products and textiles are also selling very quickly, but there is a lack of reasonable management.

While the lord was still approving and studying the report, Heidi took out all the penicillium she had stored and prepared to do animal experiments.

She extracted a total of about three grams of penicillin, the purity of which could not be confirmed, and the quantity was very limited.

Under the only conditions, if you want to ferment this substance in large quantities, you need a large enough container.

At the beginning, the container of beef soup was changed from a small dish to a deep bowl, and then all the way to the largest clay pot, which required constant stirring and extraction——

After observation, Heidi found that the mycelium will begin to decay after growing to a certain extent.

They must be collected in due time and either extracted into a solution or ground into a powder.

The current dose may be able to treat moderately large or small inflamed wounds, but it is absolutely impossible to widely promote it.

The two rabbits that Leonardo da Vinci gave her had already given birth to two litters of little ones, and they are still alive and well.

Heidi couldn't bear to hurt them, so she bought another chicken, cut off some of its feathers to expose the skin, and then cut its legs with a knife.

Naturally, it was inconvenient for her to control such a calling animal alone, so Da Vinci helped her hold the chicken in the yard, and while neatly tying its mouth with a rope, he watched curiously what she was doing. What.

"Hey, Heidi, would you like to drink another glass of wine?" Botticelli appeared next to him, raising his eyebrows suggestively: "Just say that the angel came again."

Heidi was still busy writing the experiment diary, so Da Vinci flatly refused.

"She has been very busy recently, and the barrel of wine should be taken out next year."

Botticelli held an empty wine bottle quite innocently: "I didn't talk to you."

"Okay—but wait a few more days, the wine will taste better when it's hot." Heidi finally finished treating the chicken's wound, and began to pray in her heart that it would not die of tetanus.

To make sure it was colonized, she even dabbed some Staphylococcus aureus powder, which she had collected earlier, on the edge of the wound with a glove.

Syringes have appeared in the Middle Ages, but the way of using them seems a bit scary...

In addition to rough blood sucking, some doctors tried to use this long and thick needle to suck out the cataracts in the eyes of old patients.

——Heidi couldn't find any suitable evaluation for this kind of genius idea.

Sure enough, after six or seven days, the poor rooster was dying in the cage.

Although there has been a steady supply of grains and clean water, the wound on its leg has obviously begun to fester and inflame, and pus is faintly leaking out.

Da Vinci saw that she cared so much about the rooster, and at one point suggested to cut off the affected part to see if it would be good.

When the inflammation turned from mild to severe, Heidi diluted the previously extracted penicillin and took a simple skin test on the other side of it——

No problems, no fatalities.

She then injected a tube of the solution into the affected part of the cock and started the follow-up treatment.

Those previously extracted are not at all adequate for the long-term treatment of an adult human, but more than enough for animals.

When the injection was given on the fifth day, the wound had healed to the point of scarring, and the big rooster seemed to have regained its spirit, crowing at three o'clock in the morning.

Da Vinci helped her hold down the chicken, and showed her his daily sketches of the wound, which were indeed lifelike.

"What did you inject it with?" He studied the tube of fluid. "Is this what you got from the mold on the orange?"

Botticelli reappears with a book in his arms.

"Heidi—I borrowed Chaucer's Palace of Fame, but it's all in English. Should I hire someone to translate it?"

Da Vinci pressed the struggling cock with both hands, and looked up at him: "Mr. Alessandro Felipepe, can't you see that she is busy?"

Heidi suddenly raised her head: "Yes——I've been looking for that one! English is fine, I can understand it!"

Da Vinci gave her a strange look: "You can speak English?"

She signaled Botticelli to wait for herself, untied the rooster and put the rooster back to rest. Standing beside him, she washed her hands and said, "Learning English is the beginning of learning more knowledge—you should also get in touch with it."

Botticelli waved the book in his hand with a smile, beckoning her and himself to go to the other side to talk about other things.

Da Vinci tried to call her back: "Wait, you haven't explained to me about the tube of liquid."

"I have already submitted the paper, and if there are no accidents, it will be published in the Florence Bulletin." Heidi waved her hand: "Come and see you at the old time tomorrow."

Da Vinci watched the two of them move away, and wanted to keep her, but he couldn't think of any other reason.

Then...see you tomorrow.

The idea of ​​the "Florentine Bulletin" came out before the outbreak of the war.

At that time, Heidi knew that she was going to Milan for vacation for a while, so she wrote a penicillin research progress report and related specific suggestions for his reference in advance.

It has to be said that the existence of newspapers is still very necessary.

As early as the ancient Roman period, there was a similar design in Europe. People erected a wooden sign in the Roman Senate to regularly record various decisions and announcements, which was called "Daily Records".

With the expansion of the territory of Rome, the "Daily Chronicle" was gradually converted into cloth with written words, and was taken to the state residences of various provincial capitals by special personnel.

Heidi suggested the establishment of a movable type printing house, and also wrote a complete set of publishing procedures.

It doesn't have to be too fast, a week is fine.

Movable type printing itself requires time for typesetting and editing. More importantly, the existence of newspapers should not be to convey information, but to guide public opinion.

At that time, before parting, she stood in front of Lorenzo, and her words were short but powerful.

"You must want more people to hear the voice you want them to hear."

To control the newspaper is to control the machine for disseminating public opinion.

Lorenzo did exactly that.

Not only did he select a suitable editor in just a few months, but he also published the first issue in the fastest time, and began to fumble and issue one edition after another.

Although the cost and price are a bit expensive, it is also attractive enough.

He selected suitable candidates from the academy to write some not-so-sophisticated articles, as well as reports on trivia between the various city-states, and very cleverly made people start writing some "Ten Days Talk"-style short stories in the side column.

When Heidi saw that bloody and popular story appeared in Italy together with newspapers, she sincerely felt the business talent of the Medici family for a while.

In fact, stories like "Ten Days Talk" are more difficult to describe than the contemporary entertainment tabloids.

On the way to Milan, she read many of the stories in it, and was speechless for a long time.

The deepest memory is that a beautiful woman frequently cheated with her lover at home while her husband was out.

When her husband came back suddenly, she asked him to scrub the huge wooden barrel with her. The two of them bent down and leaned into the barrel, and she pointed out the specific areas that needed to be wiped more.

And the lover stood behind the woman, continuing to do whatever he wanted...

This kind of story seems to be not uncommon in the Middle Ages——

Up to now, even the existence of illegitimate children has begun to be generally accepted, and Mr. Medici, who has not had any illegitimate children for a long time, was once praised for his virtues.

Later, when reading the new newspaper every week, Heidi would occasionally glance at Da Vinci subconsciously.

Some stories are too bad to tell, more embarrassing than certain scenes in public bathrooms.

After reading those stories, she looked at the painter who was concentrating on studying the tail feathers of pigeons, and she felt a little incredible.

In a country where such customs are prevalent, there are still such pure and undivided people.

He will build a strong city wall, handsome in appearance and elegant in speech, but he will not have any distracting thoughts about women or men.

—Maybe this is an angel.

-2-

On the sixth day of the injection, the cock finally got better, and the previous inflammation and pus completely disappeared. Obviously, the experiment was successful.

This - is really incredible!

Compared to the plastic surgery she designed independently in modern times, compared to the miracles of the new era, the penicillin she made by herself can be used successfully, which makes people want to dance here happily.

This is the ignorant and backward Middle Ages... She actually did it!

Heidi wrote a detailed report on this and submitted it to the lord in time.

She suddenly had two bold ideas, each of which required time and money.

The first one is to build a workshop large enough to store larger volumes of penicillin with containers as tall as one person or even higher.

Before the advent of antibiotics, one of the causes of death in wars was not only the killing of bullets, but also the inflammation and infection of people's various wounds.

If we could make bigger containers and allow more strains to ferment at a faster rate, maybe we could make enough penicillin to save people's lives!

The second is to find new strains.

This is all due to her accidental discovery——

Due to illness, the cucumbers on her fruit plate had not been eaten for a long time, and Penicillium was also affected by damp.

When Dejo was about to throw them away, Heidi stopped him and decided to try to experiment with Staphylococcus aureus again.

It actually had the same effect.

She didn't know which plants Penicillium would exist on, and whether there was any difference between them.

But the growth rate of the mold on the cucumber is much faster than that on the orange peel——

"My lord, this may be the same as planting peas," Dejo muttered, "Obviously they are all planting beans, and the ones in the south that bloom less just grow faster."

Is Penicillium also sub-species?

Heidi thought for a long time, and decided to find a copy of all kinds of cyan and light green plants, and record and observe their different conditions of mold.

Leonardo da Vinci had paintings and theater commissions to do, but he couldn't bear to go to her laboratory to have a look.

Lorenzo pointed her to a new independent workshop near the Lord's Palace. Not only can there be a larger space for various experiments, but also the bunch of rabbits can have fun and graze in it.

Every time Da Vinci came over, he would happily help her observe the degree of moldiness of those melons and fruits, and remember to tell her about the condition of the chicken afterwards.

Sometimes Heidi would suddenly want to wrap this chicken in bread crumbs and salt and fry it, and it would be better to sprinkle some black pepper powder.

...Is there black pepper in this era?

There really are, but they are very expensive, so expensive that it is more difficult to pay than that spoonful of purple dye.

Heidi, who considers herself a little rich woman, decided to eat salt-baked chicken after learning about the price.

...It's better to be modern.

It took a long time for the lord to give feedback, but the content was comprehensive and thorough.

He agreed to Heidi's request to establish the 'Penicillium Workshop'.

After all, these things only need to pay less than ten gold coins per month, which is really nothing compared to the artworks he bought and the property he took back from the moths.

In the entire Ducale Palace, apart from those surnamed Medici, the richest person is probably Botticelli.

He can get more than 100 gold coins for a painting, and there are various rewards from time to time, and his status is like a member of the Medici family who grew up.

In addition, he also opened a two-story painting workshop, employing various sculptors and painters to do the work for him, and he only needs to sit and count the gold coins.

When Heidi was instructing the workers to build the huge mixing tank, she suddenly thought of these things and had some inspiration.

Shouldn't she... and should, find some bigger business for herself?

For example, selling oil paints, or opening multiple chain textile workshops?

The mechanical tables of the Penicillium Workshop were all designed by Leonardo da Vinci, and he obviously helped the industry a lot.

It can even be said that he seems to have nothing he doesn't know.

In this era, the top-stroke waterwheel has been created, and the kinetic energy structure and fuel are constantly improving.

She originally estimated that she would send workers to carry out round-the-clock rotary stirring, but was completely replaced by the linkage machinery he created.

This made Heidi suddenly think of the days when she invented the frequency hopping communication patent——

She is responsible for proposing abstract concepts and ideas, and the professors of Caltech are responsible for concrete construction and creation.

But compared to those professors, Leonardo is a completely self-taught genius.

He loves books, engineering and art knowledge, and when he is tired of drawing sketches, he will play a piece of lyre for her.

And there is no possibility of hurting her.

When the construction of the penicillium workshop was on the right track, she couldn't help but went to his workshop.

"Do you have any other plans?"

"Can you show me?"

Maybe dig a little more, let him shine more light in advance, and the whole of Florence will be sheltered.

Da Vinci was working on the final coloring part of the portrait of the lady, and motioned her to wait for a while.

His brushstrokes are very textured, and even the lightness of the skin like egg white can be intuitively expressed.

Heidi watched for a long time, and subconsciously began to help him mix the tempera and refill the wine that he had been drinking.

——It was bottled in a glass bottle with a cork stopper, the effect is quite good, and you can smell the fresh aroma when you pour it out.

Da Vinci is prone to forgetting himself occasionally when he devotes himself to it. When he finally stopped to rub his neck because of muscle soreness, he remembered that there was another person standing beside him.

Giotto's bell tower duly began to chime, telling him that three hours had passed.

"Sorry, I just wanted to fill that side," he subconsciously stood up, and apologized to the temporary assistant: "I kept you waiting for so long..."

Heidi was quite calm, she was used to this way of getting along.

Both of them were busy with different things, and both were stuck in quiet and orderly thinking.

No gossip, no contact - not even eye contact.

Very independent and very natural.

In order to apologize, Da Vinci took her to a nearby tavern to eat fresh stew, and when both of them had a rest, he took her back to the workshop to see the manuscripts he had accumulated before.

The candles were dimmed, the nightingales were chirping, and the atmosphere seemed like a date.

But Heidi flipped through these manuscripts intently, completely treating him as a reliable friend of the same sex.

Maybe other men would have some impulse at this time, but Leonardo probably wouldn't.

He is very interested in lifting equipment and perpetual motion machines, and the manuscripts of various simulations can be written for several pages.

In addition, there are strange-looking mechanical birds, flying machines, screw jacks, and an existence that looks like an old record.

"Leo, what is this?"

She held up a notebook and beckoned him to come over and read the note.

"This is... a needle grinder." Da Vinci pulled out a charcoal pencil and marked a clearer arrow next to it: "Look, once this person pushes this gun, this grinding device and polishing belt can be used to grind needles. "

"Grinding needles?"

"Yes." Da Vinci pointed to the three lines of small characters in the lower left corner, and translated the mirrored Italian to her: "According to my calculations, one hundred such machines can grind forty thousand needles per hour." , and each needle is worth five silver coins."

Heidi froze for a moment, and began to quickly calculate the total number.

She was not familiar with the exchange rate between Florentine gold coins and silver coins, but now she is almost the same as the natives.

"The annual income is about - [-] gold coins?!"

Sixty thousand? !What kind of concept is this - in this era of small family workshops, it can create a turnover of about [-] gold coins!

What military spending does the Medici still lack? !

"What? Is it strange?" Da Vinci was a little at a loss: "It should be this number."

"What amazes me is—have you ever considered the idea of ​​selling, or making money from it?" Heidi tried to give him some inspiration: "With these gold coins, you don't have to draw for anyone at all."

The other party shrugged, obviously not paying attention to those things.

"I prefer creation." He corrected: "As for coins and so on, it is enough to have food and clothing."

She took a deep breath, and suddenly felt helpless when an old man met a child.

In her previous life, she experienced investment failures in several movies and real estate, and she also fell into financial difficulties many times in her middle age and later years.

Many of her insecurities also come from these memories.

Otherwise, I wouldn't let that ruby ​​ring disappear into the black market.

...Although she didn't know why Medici refused to return the ring, she accepted it.

Years of financial distress have made her feel insecure now.

There is no savings, no long-term development industry, and it seems that at any time, we will return to the days when we cannot even cope with basic expenses.

On this point at least, Lorenzo was generous enough with his salary to be called kind.

The gold coins he paid her in the past three years have been carefully stored and almost untouched.

Now relying on this rather strong start-up capital, she can find ways to make herself own an industry that can develop stably, and may even join the ranks of emerging bourgeoisie in the future.

"But when it comes to salary, I basically don't have to worry about that now." Da Vinci picked up another scroll sideways and showed her the design pattern inside.

She saw the river branching and converging like a blood vessel, and the city of Florence standing beside the river.

"This is……"

"It's the planning map of the city's water canals." He laughed: "Thanks to you, I have just been appointed as the water conservancy engineer of this city-state."

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