fall in love with a mentor

A few weeks later, Junyi had his plaster cast removed, and his arm was almost recovered. At the same time, Jiaxi's QE was imminent.Junyi organized a short meeting to practice QE for Jiaxi. Two classmates who had QE before also experienced such a drill. After being brutally slaughtered by Junyi, they passed the QE smoothly.Jiaxi had already prepared well in order not to embarrass herself in front of him.Jiaxi, whose English level has improved by leaps and bounds since Junyi's arrival, completed the presentation very smoothly, but facing Junyi's sharp gaze, he still gasped, this bastard is really a natural actor!Although everyone has long been used to Junyi's merciless censure at regular meetings, they are used to his tenderness. It was the first time that Jiaxi was questioned so trickily by him, but she still couldn't stand it.

"May I ask why you chose this structure as a ligand for an anticancer drug?"

"This is because……"

"Don't tell me this is the structure your mentor gave you!"

Is this true?Jiaxi thought. "because……"

"Why use ketone instead of other structures, why use a pyridine ring, why use phosphorus, there are many elements that can be used as gold ligands, it makes sense to choose phosphorus, right?" Forced, Jiaxi has no room to breathe.

Jiaxi was dizzy by this series of questions. Before that, he focused his energy on the principle of reaction, but unexpectedly, Junyi tricked him on such irrelevant technical issues.Anti-cancer gold complexes are currently in the experimental stage, even if there are very few animal experiments, so at this stage it is basically a matter of finding a needle in a haystack, which is a matter of luck.It was luck that Jiaxi ran into an active structure.If you have to ask specifically what should be designed into such a structure, it is really very difficult to answer.Most of the drug development is actually looking for the cause from the result. After knowing that this structure is active and the other structure is not active, the reason can be analyzed.The design of these compounds of Jiaxi is mainly based on the reactions that they can complete at the present stage, so the selection range of functional groups is actually very narrow, and it is impossible to design as one wishes.

Seeing that it was impossible for Jiaxi to answer this question, Junyi turned to another question, "What is the difference between cancer cells and normal cells? Structure? Genes? Why can normal cells become cancer cells? Your On what basis is the drug able to selectively kill cancer cells instead of normal cells?"

This is indeed a very sharp question. It is very difficult to explain the reason at the stage when the principle is not clear. The difference between cancer cells and normal cells, this kind of biological problem, is almost no longer within the scope of my own research. Jiaxi It is even more unexpected that someone would ask such a "layman" question, because this kind of question is the basis for people who study biology, just like why water is water.

"There are many differences between cancer cells and normal cells, but the differences between different cancer cells and normal cells are very different..."

"Are you trying to twist your tongue?" Junyi interrupted him in a cold voice, "What I want to ask is the essential difference between cancer cells and normal cells, the basic characteristics that separate the two, just like the boundary between men and women Clear things should exist, right?"

Looking at the speechless Jiaxi, Junyi finally asked a question related to chemistry, "Why does your gold complex have a linear structure?"

"One-price gold is mostly linear."

"That's the answer you take for granted."

But what does this have to do with my research topic? What I am doing is anticancer activity and not structural research?

"Monovalent gold complexes are now a popular catalyst. If it is only a linear two-ligand structure, how can it be used for catalysis, and the dppe you mentioned in the preface is a four-ligand planar structure."

"But the most stable is the linear structure."

"Then why?"

"because……"

Finally being approached at a dead end, Jiaxi could only stand there blushing and listen to the teachings.Junyi finally sighed, and the deep sense of love and responsibility is what I mean, "Finding out why these things is what we need to do, don't let your thinking be blocked by taking things for granted." Looking across the others, Junyi Yi looked at his watch and said with a smile, "Who will save him, otherwise we will have to spend time here, and I don't know when we can eat."

People who don't know about this problem can't help. A brother who has also done gold compounds only knows that it has something to do with the electron cloud, but he doesn't say why.Junyi shrugged his shoulders, came to the blackboard, and began to draw the electron cloud map, then carefully analyzed the electron orbital hybridization of gold, and then expanded to talk about the change law of the entire family and the characteristics of the entire cycle , proposed the concept of lanthanide contraction.Seeing that the blackboard was already full, Jun Yi looked at his watch again, and jokingly said, "Thanks to Jiaxi, our dinner time has been postponed by more than an hour, forget it, I will treat you to a meal today, to celebrate I'm back from injury!"

Bastard, you came back from injury, but when you came back, you severely injured yourself, it's too sad.Jiaxi blushed and did not speak, thinking that he only spoke for 10 minutes, but Junyi asked for more than an hour. He seemed to deliberately not ask any of the questions he had prepared, and either he did not answer his questions at all. , or the answer he gave him has been full of loopholes, Jiaxi now feels like her body has been beaten into a sieve, leaking everywhere.

In the evening, Jiaxi was busy until very late to fill in the loopholes. When Junyi came to tell him to get off work, he realized that it was past ten o'clock.Seeing Jiaxi was silent all the way, Junyi said softly, "You were hit hard because of today's meeting, right? I have read your review materials so I skipped all the questions you already know. There's no need to ask you any more, right?"

I see!I thought that what I reviewed was worthless. "No, I'm not a person who doesn't distinguish between public and private, I'm just a little worried." Jia Xi told the truth.

"I'm just helping you fix the loopholes. Of course, what you prepared is the key point. You don't have to doubt this. If your examiner asks the questions I asked today, it means they have a problem."

Oh, it turns out that you are the only one with the problem. "However, you still impress me?" Jia Xi said very sincerely.

"what?"

"Why is it not your research topic, and you know it in such detail?" When Junyi talked about the multiple hybridization orbitals of gold on the blackboard, Jiaxi was really surprised. What Junyi did was palladium. , has nothing to do with gold, the more advanced each person is, the narrower the scope of research will actually be.

"Ah, what are you talking about? If you asked me before this, I wouldn't know. It's just that when I read your report again, I noticed this problem and checked some documents." Junyi laughed, " Of course, use this opportunity to show off your mentor’s excellence! Don’t believe that your mentor is omnipotent, they are just good at covering up their own incompetence, because his knowledge circle is only outside your knowledge circle Just a little bit, if you break through this range, you will know that your mentor is not that amazing!"

But even in this realm, I can't keep up in my life, Jiaxi thought.

"But the most brilliant part of my question today is not here!" Jun Yi looked at Jia Xi expectantly, as if ready to accept worship, but was poured cold water by Jia Xi, "What?"

"So I didn't understand it thoroughly! Don't you have three examiners?"

"Yes." Jia Xi baffled him.

"Leungwenki has done some biology stuff, so he might ask you some biology questions, so you should be prepared. Tannuansong's research field is completely out of line with yours, but he likes to ask some boring questions Questions like the difference between cancer cells and normal cells, and that person always has a skeptical expression no matter whether your answer is right or not. Don't be fooled by him. You have to confidently say that's it, anyway. He must not understand." Seeing Jiaxi looking at him with strange eyes, Junyi laughed and said, "The tutors are all good at acting!"

"And one more?"

Yamaki is Japanese. His questions should be basic questions in the field of chemistry, reaction mechanism, conditional control, etc. His only problem is English pronunciation. "

"I said that your investigation is too clear, right?" Jia Xi said sarcastically.

"I know you only pay attention to your own aspects, but you know yourself and the enemy, and you will win every battle, so I will help you pay attention to these aspects, I hope it will help you. As for Yamaki, didn't you work with him as an examiner before, that The student couldn't understand his English at all, even though he repeated a very simple question five times, the student kept saying sorry, and finally I had to translate for him."

So that's the case, did you think that the dignified tutor has become a paparazzi who specially inquires about the tutors' gossip?

"I can't see you fighting with other heroes." Junyi said regretfully after a while.According to the school's new regulations, tutors cannot attend the students' QE, otherwise they will put pressure on the examiner.

Jia Xi thinks this is a good rule, if she is stared at by his talking eyes, she might be even more nervous. "Talk against the heroes? It's almost as good as being slaughtered."

"Hehe, it's not that serious! But seeing the little lambs being slaughtered obediently, isn't it a very happy thing?"

"Look, this is showing your true nature, pretending to be self-serving!"

"That's right, thinking of the miserable situation when I was a student, I can't help but want to make things difficult for them." Jun Yi shamelessly said his dirty thoughts.

"How can you be so quick and quick?" Jia Xi sarcastically said.

"Why not? When I was defending, the examiners almost cried. They said that my reaction mechanism was not supported by enough evidence, and asked me to go back and do the experiment again. I was delayed for a month before passing the defense."

Seeing his serious expression, Jiaxi didn't seem to be lying, and gradually realized that Junyi's schooling journey was not smooth sailing. After experiencing many setbacks, he achieved today's achievement.But I was completely under his protection, grateful and ashamed.

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☆、Airport agreement