The princess has been pregnant for eight months. She has gained weight recently and looks a little round and jade-like.Because she is nourished by Zhongyuan Dianhong's internal energy every day, her complexion is very rosy, and her body looks better than before she was not pregnant.

Although Yinzhou has entered autumn, the sun is still very strong, and it is dry during the day.It was very stuffy in the room.

The princess was only wearing a thin layer of silk, and she was lazily nestling on the mat, with two little maidservants fanning her.

There was a large basin of ice in the room, and the two maidservants were standing in front of the ice basin, and the wind from the fan carried the cool air of the ice cubes.

A little red opened the door and came in, holding a beautiful small glass bowl in his hand, in which were various kinds of diced melons and fruits, almonds, dried apricots and the like, and poured a layer of cheese on top.

This is the cheese bowl.

The princess is pregnant with a child, her body temperature is a little higher than usual, and she is more and more afraid of heat and greedy for cold.Moreover, in such a hot season, she doesn't like to eat even more. In order to make the princess eat more, the small kitchen is also cooking in different ways.

A little red walked in, sat straight on the bed, Li Yu glanced at him sleepily, stretched out his hands, and a little red followed suit, and hugged her in his arms.

But his body temperature is not low. The princess likes to be hugged, but she feels hot. After being fed two bowls of melon, fruit and cheese, she softly pushes him away, and continues to squint and half sleep.

A little red was pushed away, but she was not angry, she just whispered: "Do you still want to eat?"

Li Yu said with an air of gossamer: "I don't want to eat..."

Not forcing her to turn red at all, he came up and kissed the corner of her lips, and said, "Sleep for a while?"

Li Yu nodded.

Yidianhong lays down with her, but does not hug her.

The body temperature of pregnant people will be a little higher than normal people, so they are more afraid of heat. The night in Yinzhou is so cool, Li Yu is still too hot to sleep.She wants a little red hug for a while, and pushes him away and ignores him for a while. She is very capricious.

Seeing her suffering like this, Little Red naturally felt uncomfortable.

If she hadn't conceived the child, she wouldn't have suffered so much.

Yidianhong sighed, reached out and patted her back to comfort her to sleep.

The princess slept for about half an hour, then woke up drenched in sweat, a little red, and carried her to the bathing pool to take a bath, she was refreshed, and then she changed her clothes and came out.

During the period from waking up to taking a nap to the evening, those who have something to look for the princess have to hurry up and ask for a meeting, because the princess is not in good spirits, and only this part of the day is the most energetic and able to listen to people's reports.

The person who came here today was actually Ximen Chuuxue.

He stayed in Yinzhou for a while before, and left after learning some new medical skills.It just came back suddenly yesterday.

Ximen Chuuxue has always been a person who doesn't like to be busy or talk nonsense. If he came to visit specially, he must have something very important.

Li Yu listened to the report and said, "Call him in."

She was wearing a coat, and Ximen Chuuxue had already walked in.

He is still dressed in white and has a black sword, like the deepest snow.Such a person seems to be supposed to cultivate the path of ruthlessness, short love and absolute love.But Ximen Chuuxue also got married a while ago, and his partner was Sun Xiuqing, a heroine of Emei.

Although Li Yu and Ximen Chuuxue hadn't met a few times, Li Yu felt that they were friends, so when she met Ximen, she smiled and said, "I haven't congratulated you in person yet!"

A smile appeared in Ximen Chuuxue's eyes.

This is really a rare thing, and it seems that feelings have changed him.

He said lightly: "Thank you."

Li Yu said again: "I asked Lu Xiaofeng to bring you a congratulatory gift, I don't know if you are satisfied."

What Li Yu gave was a new type of silver mirror.

The silver mirror is another major technological advancement since the large plate glass.

And Li Yu's partner, Jiangnan Huajia, is also very strong. In just a few months, the sales of flat glass and silver mirrors have all opened up.Although ordinary people can't afford this expensive but luxurious item, princes, nobles, wealthy merchants and wealthy people rush to buy it.

But no matter how good things are, if you buy too many and flood them, they will not attract people's attention. As a person who is used to the marketing strategies of modern businesses, Li Yu has also formulated some strategies.

The first is to set a high price... It is originally positioned as a luxury product. If the price is low, it will be looked down upon by others, just like a famous windbreaker brand in Great Britain. Clothes that cannot be sold would rather be thrown away than discounted, because discounted Means a reduction in style.

The second is hunger marketing. After confirming that the silver mirror and flat glass had aroused the purchasing enthusiasm of the nobles in the capital, Li Yu restricted the output instead.

After all, most of the time, people need to compare, and the nobles are no exception. We don't deal with each other. My family has yours but I don't. Doesn't this show that my connections are wider than yours, and my face is bigger than yours.

Li Yu decided to maintain this pricing strategy for a long time, and she set the glass factory as a first-level confidentiality point early on. Li Yu gave them very high benefits, so they should also accept the corresponding not free.

So Li Yu gave Ximen Chuuxue a big full-length mirror, sincerity is enough.

But it was more embarrassing for Lu Xiaofeng.

The silver mirror is exquisite but fragile. When he saw the huge package, he was speechless.

Of course, Lu Xiaofeng with four eyebrows can always solve all kinds of troubles perfectly.

This gift is not so much a wedding gift for Ximen Chuuxue, but rather a gift for Sun Xiuqing. Girls always like to change into bright clothes of various colors. Li Yu himself has a lot of clothes and jewelry. At this time, A huge full-length mirror is key.

When she first came to this world, Li Yu was quite unaccustomed to a world without silver mirrors. When the Korean merchants presented the silver mirrors a few months ago, she was overjoyed.

Of course, the people in the princess mansion were amazed again.

So clear, it is a magic mirror that only gods can have!

No wonder it sold so well.

Ximen Chuuxue recalled his wife's frightened, admiring, and happy look when she saw the silver mirror, and a warm smile appeared in her eyes.

He said: "The gift is very valuable, thank you."

Li Yu smiled and said: "The gift you gave me is also very good, and I also want to thank you face to face."

When Li Yu got married, he also gave him a gift—a sharp and decisive sword.

Ximen Chuuxue's intentions are of course good, but Zhongyuan Yidianhong is used to using thin swords, and he has an aloof personality, so he doesn't like to use things given by others.And Li Yu...how could Li Yu be interested in the sword?

So this sword, of course, was well kept in the treasury.

Even so, thanks are still to be thanked.

Ximen Chuuxue is not a person who pays much attention to etiquette, so he nodded casually and started talking about business.

He said: "Smallpox has become popular again in the south of the Yangtze River."

Li Yu was taken aback.

Her brows were immediately frowned tightly, and she repeated: "Smallpox?"

Smallpox, a severe infectious disease, has a high fatality rate.This is an ancient and terrible disease.

In ancient times, hearing the word smallpox was even scarier than hearing the word Hades. If someone got smallpox, one foot would have stepped into the gate of hell.Even if one survives smallpox, the face and body of the cured person will be left with dense acne scars, which are very terrifying.

In modern times, smallpox has disappeared.

In 1980, the World Health Organization announced the complete eradication of smallpox virus in human beings-of course, this is the only infectious disease eradicated by human beings.

Of course, Li Yu had never seen a patient infected by smallpox.

This matter is very serious, so serious that Ximen Chuuxue, a person who only leaves his house four times a year, came straight to Yinzhou.

Ximen Chuuxue continued: "I wonder if you have a solution."

His voice was very flat, but his mood was not calm.

Throughout the ages, I don't know how many doctors have tried to find a solution to smallpox...but no one really knows how to cure smallpox and avoid smallpox.

For some reason, Ximen Chuuxue just had a vague premonition.

That is - Li Yu might really know something.There is no evidence for this premonition, but Ximen Chuuxue still came, just to ask her face to face, is there anything you can do?

Li Yu said: "There is no specific medicine for smallpox."

The smallpox virus has a special drug called Tecorviril. However, when the drug came out, the smallpox virus had been wiped out on a large scale, so it has not been tested on humans, and only animal experiments are used to confirm its effectiveness.

But here, too, Turkowry doesn't make much sense, because there isn't and there can't be.

Ximen Chuuxue was silent for a while, and said, "I see."

Said, turned to leave.

Li Yu said again: "But it can be prevented."

Ximen Chuuxue stopped in his footsteps, he didn't speak, he was waiting for Li Yu to continue.

Li Yu said: "I don't know if you know that if a person who has had smallpox survives by chance, after he recovers, he will never suffer from smallpox again for the rest of his life."

Ximen Chuuxue is not a full-time doctor, he has not tracked the life of the cured person, but he has heard about it in the medical book, so he said: "I read it in the book."

His brow furrowed.

In addition to writing about this phenomenon, medical books also wrote about a "pox clothing method" to prevent smallpox. Specifically, it is to put the clothes of the patient on normal people, so that normal people can also be infected with smallpox, so as to prevent smallpox during the disease. Gain immunity after recovering.

however……

However, this method is not to let people actively be infected, and then resign themselves to their fate to see if they can live?

Ximen Fuxue thinks this is really unreliable.

He said directly: "The method of acne clothing is not advisable."

Li Yudao: "I know it's not advisable, but this way of thinking is advisable. If there is a disease similar to smallpox, people will not die after suffering from it, but it can also make people immune to smallpox from now on, which can prevent it." effect."

In fact, there is a method of vaccinating human pox that has been handed down in China. In addition to the pox clothing method that Ximen Chuixue just mentioned, there are other pox paste methods, dry pox methods, water seedling methods, and so on.

It is a very advanced and correct idea to actively infect to obtain immunity.

But there is a problem with the early human pox, that is, the ancients had no way to screen the attenuated strains.

For example, the pox clothing method is equivalent to asking healthy people to infect smallpox. Whether they can live or not depends entirely on their lives.However, the pox clothing method was the first method of human pox vaccination, and later the Chinese people also made many improvements to this method.

And the pox paste method refers to dipping the pus from smallpox patients' pox with cotton, and then stuffing it into the nasal cavity of normal people, so as to infect normal people.

The Qing Dynasty also developed the "cooked seedling method", which is a bit like the "attenuated vaccine" in modern immunology.

The method of vaccinating smallpox to prevent smallpox originated in China and spread to other countries. Later, in the UK, the method of varicella was improved several times, and the country doctor Edward Jenner discovered through observation that it was difficult for milkmaids to get rid of it. Suffering from smallpox, he invented the vaccinia method, which is safer than human pox.

Moreover, she has not read the vaccination records of the vaccination method, but the vaccinia method is too famous and has many records to check, so she is more familiar with this method.

She said decisively, "Vaccinate."

Ximen Chuuxue had never heard of cowpox, so he frowned and asked, "Vowpox?"

Li Yudao: "Vaccinia is a kind of pox that occurs on cows. It is similar to human pox, but the toxicity is much lower. There will only be a few herpes on the body, and it will not harm your life. Many cowherds will get it. Afterwards, you will be immune to smallpox."

Ximen Chuuxue had never heard of what she said, and this method was never mentioned in the medical books he collected.

However, what the princess said was very certain.

As a frontier city, Yinzhou naturally has cattle and sheep farms, and of course there are people who have had cowpox in the cattle farms.It's just that there has never been smallpox in Yinzhou. How did the princess observe this phenomenon?

However, Ximen Chuuxue didn't ask too much. There are too many mysteries about this princess. He doesn't pay attention to other things, only talking about medical skills. This kind of magical medical skills is like a foreigner. feel.

He said lightly: "You can give it a try."

Because I have seen similar methods before, and I know that the cowpox is not fatal, no matter what, I can't go wrong if I try it.

The princess also said: "I was negligent, this matter should have been put on the agenda long ago."

In ancient times, many diseases were hidden.

Yinzhou people now have a preliminary concept of hygiene. Sewage and clean water are separated. Raw water will be boiled and evolved before drinking. Alcohol is also sold in Huichuntang. If you have a wound on your body, you can use alcohol to wash the sand in the wound , to prevent infection.

If you are already infected, you have to send it back to Chuntang immediately. There is a special drug penicillin available in Huichuntang, but the production of penicillin is not high, and there is often no stock, so we can only resign ourselves to fate.

There is also the saying that you should wash your hands before meals and after going to the toilet. There are all kinds of cleaning products sold on the street-what kind of bath beans, acacia, soap soap, etc. Even poor families know to use plant ash or rice water to cleanse clean yourself.

There are also several sanitation workers on duty on each street. Livestock are not allowed to defecate on the street. If there are livestock, the owner has to be responsible for its cleaning.

Under Li Yu's three or four years of work, Yinzhou has become a clean and hygienic city. Good living habits can resist the invasion of some diseases.

But...not all of them.

If smallpox is contagious, the Princess Mansion will naturally isolate the patient very quickly, but this is a method of passive resistance after all, if it can be prevented, it is of course better.

but……

The establishment of a concept is not easy after all.

Li Yu sighed: "Just asking people to spontaneously infect one disease to prevent another disease doesn't seem to be easy to win people's trust."

In the Qing Dynasty, vaccination was already known to many people, so it was not difficult to promote it, but in this era, this technology seems to have just begun to develop, so...

So vaccination or something is really unheard and unseen.

Li Yu said: "In this case, let's publicize it first, and do things step by step."

Smallpox is a severe infectious disease, and it is now prevalent in the south of the Yangtze River. Although it is far away from Yinzhou, it really has to be prevented.

And in her heart, she still didn't want to benefit only the people of Yinzhou.For other things, because of her limited energy and limited authority, she can't control other things.However, if the benefits of vaccination can be publicized, then everyone in Daye can be spared the suffering of smallpox.

Then, Yinzhou has to be used as a "pilot city". As long as the effect is seen, it is not afraid that other places will not follow suit.

In fact, Li Yu felt that as long as this method proved to be effective, the emperor would definitely promote it.

After all, in the midst of severe infectious diseases, everyone is equal, regardless of whether they are poor or rich, they have to resign themselves to fate.During the Qing Dynasty, the royal family in the Forbidden City could not escape the shadow of smallpox.

Therefore, in this matter, the interests of the princes and nobles are the same, and no one wants to die.Presumably her troubled emperor brother will never have too much resistance in promoting cowpox.

Now that you have decided to do this, let's start without delay.

Li Yu is now more than eight months pregnant, and it is possible that it will come to fruition, but the matter of vaccination is really important, and she does not want to leave it to others to handle many things herself.

First of all, there must be publicity and momentum.

Now smallpox is popular again in Jiangnan area, and the word "smallpox" is the shadow engraved on the bones of the ancients.

So recently, in the streets and alleys of Yinzhou, many people are talking about the smallpox epidemic in Jiangnan.

This was done on purpose by Li Yu. If he didn't spread the news on purpose, Yinzhou, a city in the northwest frontier, is [-] miles away from the south of the Yangtze River. Who cares what life the people living [-] miles away live?

But when it comes to talking about it, it's different.

In the streets and alleys these days, you can hear horrible remarks about smallpox everywhere.

What happened was a high fever, and I started talking nonsense...the face and body were covered with blood pustules, and I was lying under the quilt, even the quilt was stained with blood, my whole body was itchy, and it was full of blood when I scratched it...finally, I inhaled less and exhaled less Many, it is simply death.

He also said that the old man in the family had smallpox, and the child cried to see his father, but was taken away by his family because he was afraid of being infected. The father struggled on the bed for more than ten days, but he did not see his child for the last time.

But the child was also infected with smallpox. The mother-in-law and wife, not afraid of the infection, took care of the child day and night, but both of them collapsed in the end. The happy family died within a month.

These terrible words, of course, made the listeners turn pale with fright.Even a person who has never seen smallpox in his life can't help turning pale with horror when he hears these two words.

what should we do?

How can this be done!

oh!Let's go ask the princess!The Rejuvenation Hall built by the princess has the magic drug penicillin, which can even save the dying people!Huichuntang is so powerful, and the princess is so powerful, there must be a solution!

The princess is a kind and soft-hearted person. Even if she kills decisively and cruelly at times, she always treats those bad guys. To the people of Yinzhou, the princess is extremely gentle, so the people of Yinzhou love her more than others. fear.

They gathered a group of people and went to the Huichun Pavilion in a mighty manner. They knelt in front of the Huichun Pavilion and asked the princess to bestow the anti-epidemic method.

Of course, the leader was sent by Li Yu, she just wanted to create such a momentum...

The doctor from the Rejuvenation Pavilion came out, and first stated the evil of smallpox impassionedly, and then said that the princess had cried for countless times when she heard that the people in the south of the Yangtze River were suffering from it. Then the anti-epidemic method was lowered, everyone rest assured!Huichun Hall has started to learn new anti-epidemic methods, and everyone will be able to enjoy it soon!

The people were of course very excited.

They thanked Dede at the entrance of the Rejuvenation Hall, turned around and went to the Princess Mansion together, and kowtowed at the entrance of the Princess Mansion.A large group of people, so mighty, this scene, it is estimated that it is difficult to see in other places.

And Ximen Chuuxue is in charge of going to the cattle farm to find sick cows and patients suffering from cowpox.

What a dirty thing this is. Ximen Chuuxue is a pampered young master, but he is a good person. Although he kills, he kills only those who deserve to be killed.And when he saves people, he will spare no effort.

More importantly, he was interested.

He has always been interested in novel medical techniques.He had also been interested in penicillin before. After the princess heard about it, she directly agreed to let him go to the penicillin factory to take a look for herself.

She smiled and said: "The reason why the magic medicine is a magic medicine is because it can save lives. Why should the prescription be kept secret? Do I want to rely on the magic medicine to make money?"

Ximen Chuuxue knew that she was really a Bodhisattva-like figure.

He just looks like a stone that can't be warmed, but he is not a real stone. The benevolence of the doctor is not easy to see in him, but it is there.

And also touched by the princess.

Therefore, with the support of many ideas for the grand plan of vaccination this time, Ximen Chuuxue simply went to do these pickling and dirty things.

And the princess was also arranging various things with her increasingly heavy body.

After some momentum, the Huichun Hall quickly established a vaccinia center to inoculate the people with vaccinia.

However, some sour and rotten scholars who slipped through the net are now acting as monsters again. They are like modern anti-vaccine people. Fa will kill people.

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