lip gun

"Go to your mother's Drug Administration!"

In a word.The guest's face turned green, the audience was stunned, the director went mad, and even Su Qinghua squeezed the handle of his wheelchair, cursing in his heart that his students would only be brave and foolish.The entire studio hall suddenly fell into a deadly silence, like a pressure cooker with its vent hole blocked, if there was a slight movement, it would explode with a "bang" sound, and rubble would fly everywhere.

Leaving enough time for everyone to be shocked and deliberated, Xing Ming counted the seconds, and before the director forcibly switched commercials or substitute short films, he repeated the shocking words just now in English:

"Screw the FDA," this time calmly, with a steady tone, and with a friendly smile that a host should have, said, "This is a line from the American movie "Dallas Buyers Club."

Another sentence.If the salary is drawn to the bottom of the pot, although it will not be leak-proof, it will not cause a live broadcast accident after all, and at most it will be punished by Lao Chen for "improper speech".I have to say, the circle is still quite beautiful.

"The film tells the story of a terminally ill patient, after experiencing the pain and despair of terminal illness, he helps himself and others in extreme ways, and strives to survive..."

Xing Ming tried his best to briefly describe the plot of the movie in neutral terms, and Lao Chen in front of the TV could see that this kid was a thief.Now he looks like a big news anchor again.Eliminate positive comments such as "brave" and "resistance" that others often use to describe the movie, and use words such as "anger" and "extreme" to put aside the relationship between that dirty word and myself.

Not only has the courage of a man, but also has the wisdom of others. He feigned a shot, obviously reciting his lines, but secretly venting his anger.

"In our country, Lu Mou, once known as the 'No.1 anti-cancer drug purchasing agent', was arrested for the crime of 'selling counterfeit drugs', and the prosecution was withdrawn by the procuratorate in January 2015, and he was exempted from criminal punishment. This news has It has attracted widespread attention from the society and has been dubbed the Chinese version of "Dallas Buyers Club" by the media, but today, a year and six months later, a similar story is happening around us again."

Xing Ming casually rolled up his shirt sleeves and continued:

"Wearing a suit and tie, my identity is the host of "Oriental Vision". The host should be impartial, neutral and objective. "Oriental Vision" has always insisted on both advocating reason and respecting human nature. Instead of the judiciary and the public, I just tried my best to dig out a bigger corner of the iceberg to see the whole picture of the iceberg and restore the truth of the incident. However, the case about Professor Xia is still clouded, and for various reasons, none of the news parties were present So now I implore those present and the audience in front of the TV to temporarily forget my identity as the host, and allow me to speak in place of Professor Xia.” After a proper pause, Xing Ming bowed slightly to the audience, appearing humble, serious and sincere, "If you allow me, you might as well give me a little applause."

There was applause from the audience.It is not inferior to the exaggerated speech made by Sheng Yu's CMO just now.

The script went wrong, everything was Xing Ming's improvisation.After such moths came out one after another, the director was already dizzy, and Su Qinghua, who was also under the stage, was relieved that this kid had made progress and knew how to close the distance between himself and the audience at the right time.

"Primary hepatocellular carcinoma, hereinafter referred to as HCC, is one of the five most common cancers in the world and the third leading cause of death after lung cancer and gastric cancer. Compared with Western countries, liver cancer is more prevalent in Asian countries. Every year, liver cancer occurs in China Both the number of people and the number of deaths account for more than half of the same population in the world, and it is the country with the highest incidence and death of liver cancer in the world. Because the early symptoms of liver cancer are not obvious, only about 5% to 15% of patients can receive surgical resection or local ablation in time However, many clinical studies have shown that systemic chemotherapy can improve the survival rate of liver cancer patients. There was no significant effect on long-term survival, with median overall survival in advanced liver cancer being only 3 to 7 months."

"This is currently the first-line liver cancer drug Sorafenib on the market. The trade name is Nexavar. It is an oral multi-target and multi-kinase inhibitor that can significantly prolong the survival of patients with advanced liver cancer." Xing Ming said from his shirt pocket He took out a board of pills from the camera and asked the camera to take a close-up shot, "I believe that some viewers are familiar with it. It is this kind of red round pill. Two boxes must be taken, and the medicine cannot be stopped."

"A rough estimate is that 1 gram of medicine is equivalent to 10 grams of gold. I would like to ask the audience friends present, if anyone with a monthly income of more than 5 yuan can raise their hand."

Few people raised their hands, and those who didn't raised their hands looked at each other, probably frightened by the high price of medicine.Terminal illness and death seem to be far away, but they are so near, and it is really frightening to be thrown over by the host so unexpectedly.

There were four people sitting at the guest table, a law professor from a famous school, the leader of the Food and Drug Administration, the CMO of the largest domestic pharmaceutical company, and a nationally renowned oncologist.The four of them are all very old and have a lot of background, and their faces are still green at the moment.

Shengyu's CMO, surnamed Guo, was looking at Candy in the audience with a look of surprise at the moment. The two people's eyebrows did not escape Xing Ming's eyes. Mr. Guo seems to have something to say."

Director Guo said: "As far as I know, Professor Xia's Alanine Sironi was purchased from a pharmaceutical company in the United States, and the research and development project was suspended. Based on it, the dosage form innovation is carried out. At present, there is no phase II clinical research in China. If it is completed, it will be declared bankrupt. It is opportunistic and very dangerous to introduce drugs that have been discontinued abroad, have uncertain curative effects and may have risks in safety. Our company cannot agree with this extremely irresponsible behavior for patients. And deeply disgusted.”

Adding insult to injury, he still didn't forget to advertise for Shengyu. Xing Ming hooked the corner of his mouth and took out another tablet: "This is Alanine Sironi produced by Professor Xia, yellow, oblong, biconvex film-coated tablet medicines, the price of a box is several hundred or even tens of RMB, and the cost of treatment for a patient is less than one thousand RMB per month.”

Before Xing Ming’s words were finished, Director Guo spoke again, holding on to the point of “suspending R&D”: “The drug has failed to be developed in the United States. Doesn’t it make Chinese patients a dumping ground and digester for inferior drugs in Europe and the United States? Even if the price It is cheap, but if the effect is not clear, it is very likely to delay the patient's condition, and the consequences will be disastrous."

The audience at the scene began to whisper that the research and development in foreign countries was suspended, and the second phase in China had not been completed. At first glance, it was really bluffing.

Chinese people's "inner fighting insider" seems to be both instinct and talent. Xing Ming did not respond to the aggressive CMO of Shengyu for the time being, but said: "On the point of whether the drugs produced and sold by Professor Xia are European and American inferior drugs Mr. Li below has personal experience, he is a patient who has been buying medicines from Professor Xia for a long time, let's listen to what he has to say."

As the host's voice fell, a middle-aged man walked from behind the stage to the front of the stage and sat in the position of the interviewee.Xing Ming asked Bale his name, age, occupation and family income, and asked him to introduce himself in depth.

Mr. Li showed his case to the camera: "I was diagnosed with liver cancer a year ago. It was advanced and it was too late for surgical resection. At that time, the hospital recommended Nexavar, also known as Sorafenib, but it didn't work for me."

Xing Ming walked up to Mr. Li and asked, "Why not?"

"It's too expensive. I'm a worker in a state-owned enterprise, and I earn more than 5000 yuan a month. There are two elderly people to support and a child to study. It's really unaffordable."

"Is there any affordable liver cancer drug that can replace sorafenib?"

"No more. The doctor said that sorafenib is currently the only systemic drug on the market that can prolong the survival of patients with liver cancer. If you don't use sorafenib, you will have to wait for death."

"But you just said that you were diagnosed with advanced liver cancer a year ago. Without the use of sorafenib, your survival period has been significantly longer than that of ordinary advanced HCC patients. Have you taken any self-help measures during this process? ?”

"It's definitely taken." Mr. Li nodded, "I think it's human instinct. When I read the cancer diagnosis certificate, I only have one thought, and that is to live. Our patient group, All of them are patients with advanced liver cancer who cannot afford Sorafenib. Before meeting Professor Xia, many of us had lost our fortunes and divorced our wives and children, but we still wanted to live. We thought of many other ways and asked someone to buy it Sorafenib imitated in India, and even synthesized raw materials by themselves.”

"Homemade raw materials?" Xing Ming frowned slightly. "In addition to weighing and proportioning, medical starch and other auxiliary materials have to be added for filling. If there is a problem in any of these links, it is very dangerous."

"It's dangerous, but there's nothing I can do. I just want to live." Mr. Li sighed, "In fact, Indian generic drugs are relatively shoddy, and we find someone to buy them online, so it is easy to buy fake drugs by mistake. Later, I heard from a patient Introduced to join Professor Xia’s patient group and provided a medical certificate to buy medicine from Professor Xia. I can guarantee with my life that Professor Xia’s medicine is definitely not inferior medicine. All patients in our group have survived the middle stage of patients with advanced liver cancer. Survival period. When my daughter was in the second year of high school, I was diagnosed with advanced liver cancer. The doctor said that I could live for three months at most, but now there is one month before my daughter will enter school. Not only did I accompany her through the most difficult college entrance examination One day, I can still see her walk into the university campus with my own eyes..." The extra few months of life are precious to this man. Mr. Li's eyes were moist, and his true feelings were revealed. He took out a folded envelope from his pocket, He stretched out his hand to Xing Ming, "This is a joint petition spontaneously signed by our patient group. There are also some liver cancer patients who came here for the name and did not buy medicine from Professor Xia. Take it easy."

Xing Ming took the petition and looked at it. There were more than a thousand signatures in black and white. He faced the camera again and showed the petition in his hand:

"Up to now, there have been 3 phase III clinical trials in the world comparing the efficacy of alanine cilonib and sorafenib in the treatment of liver cancer, and it has been confirmed that alanine cilonib has better anti-tumor activity than sorafenib, However, the tolerance is slightly poor. Because the U.S. Food and Drug Administration stipulates that newly developed drugs must be significantly better than existing drugs of the same type before they can be approved, so the U.S. pharmaceutical company finally suspended the study. However, a number of clinical studies have shown that liver cancer There are wide geographical differences in the pathogenesis of the disease, and the drug tolerance of the Asian population is generally better than that of the Caucasian population..."

Xing Ming paused, and asked the audience: "Can a drug that has good treatment prospects and is more suitable for Asian populations be defined as a failure in research and development or an inferior drug just because it is not significantly better than existing drugs in the United States?" ?”