I reach the pinnacle of life by learning

Targeted drugs were approved by the HFDA (Hua Guo Food and Drug Administration) in 05, and then entered the Hua Guo market.

The first targeted drug to enter the country is called gefitinib, which is the gospel of countless lung cancer patients.

In 17, the annual sales of gefitinib in China exceeded 1.5 million US dollars.

So far, there are more than 20 approved targeted drugs circulating in the Huaguo market.

But without exception, these drugs are produced and sold by European and American pharmaceutical companies, accounting for almost 90.00% of the cancer treatment market in Huaguo, and the remaining 5.00% include sporadic domestic drugs, Putian-type miracle doctors and Tiao Dashen.

An executive of a pharmaceutical company in China once said: "It is completely equivalent to the invasion of China by the Eight-Power Allied Forces in the 21st century."

If the level of scientific research is not good, it is impossible to be beaten in the field of biopharmaceuticals.The gap is there, which makes people melancholy.

Targeted drugs are not drugs, but cancer inhibitors.

But just like Gewei in the treatment of leukemia, if you don’t take it, you will die faster, so there are still many patients with advanced cancer who choose to take medicine to continue their lives.

Proportional to the high price of targeted drugs is its expensive investment.

When Nuoan invested in targeted leukemia drugs, it spent ten small targets before and after the research and development funds, and the unit was still a knife.

That's why Tan Zirui felt that Qiao Yu was crazy.

Qiao Yu said: "In that case, in order to celebrate our tentative agreement, let me treat you to a guest."

Since Professor Tan returned to China, Hu Chihai had been drinking for a long time, and he couldn't escape some drinking situations. Now when he heard that he wanted to eat, he frowned frequently.

But because it was Qiao Yu's treat, Tan Zirui did not refuse.

About twenty people followed Qiao Yu talking and laughing, and turned all the way to the gate of the familiar cafeteria.

Qiao Yulang said in a loud voice: "It's so late, I won't go to other restaurants, I guess there are some leftovers, you can sit in the teacher's restaurant on the second floor of the cafeteria, I'll take care of it. Take what you want to eat, don't be polite to me. "

All scientific researchers: "..."

Qiao Yu went abroad to study for three years, but the school's monthly meal allowance of 300 was still paid on his meal card on time.So much so that his meal card now has a full five-figure balance.

When the chef of Hunan cuisine in the second canteen saw Qiao Yu, his eyes lit up, and he yelled from a long distance, "Is that the one in the suit, Professor Qiao Yu?"

Tan Zirui looked down, making sure he was wearing a suit too.

But he was also sure that the chef didn't say this to him.

Damn it, he's still wearing Armani.

Qiao Yu replied with a smile: "It's me."

The chef is a fat middle-aged woman, and she said cheerfully: "Hey, it really is Professor Qiao. You are a famous person in our school! The chefs in our five cafeterias are betting which cafeteria you will visit first.

"What would Professor Qiao want to eat? I'll make it for you. The buyer just finished shopping."

Qiao Yu looked at Wang Xiaoming beside him.

He had just returned to China, and he was not very clear about the power distribution of the canteen in the school. He came to the second canteen only because it was the closest to the laboratory.

Wang Xiaoming's saliva dripped down: "Braised pork, crispy duck with hemp seeds, steamed cured meat, fried tofu with scallions, and a Xiangxi grandma's dish for dinner."

Several chefs counted the heads, said "OK", and immediately took drastic action in the kitchen.

The sound of the fire, the whistling of the wind, and the sound of zla of the hot oil being put into the pot, all of which can be heard all of a sudden, and the aroma soon spread out.

Professor Tan took chopsticks and a fork for himself, and very elegantly used a wooden chopstick as a chopstick rest, and let other tableware rest on it.

Assistant Professor Zhou yelled at a few people graciously, and went downstairs to bring a case of beer up.

Qiao Yu only had him and Tan Zirui at this table.

Qiao Yu asked: "Do you drink?"

"Don't drink, drinking affects my thinking." Professor Tan shook his head, "If you want to make targeted drugs, it's not easy to do in China. And it's not easy to talk about it. I'm working in a cancer center in Finland. For four years, I have not been able to participate in drug design.”

"Although it's too early to say, have you ever thought about why even domestic generic drugs are imported from India? Because domestic pharmaceutical factories are not up to standard, and there is no way to mass-produce them."

"National projects rarely approve targeted drug research projects, because everyone knows that it is better to buy them directly from abroad than to research targeted drugs. It is also a waste of money. It can be made by spending 50 billion abroad, and it may cost domestically. 100 billion... because it is basically equivalent to groping from 0, and it may not be possible to recover the cost afterwards."

The reason for not making targeted drugs in China can be summed up as follows: yes, but not necessary.

With this 100 billion, it is more cost-effective than researching and producing targeted drugs if it is used to build roads in impoverished mountainous areas, or to build high-speed railways abroad.

As we talked, fried tofu with green onion was served.

The other tables were served by themselves with plates, only Qiao Yu's table enjoyed the treatment of a waiter.

Qiao Yu wanted to make targeted drugs because he was at least [-]% sure that he could make them.

He is [-]% sure, while many companies are less than [-]% to [-]% and are still working hard.

According to statistics, in 2016, more than [-] people died of cancer every day.This data is extended to the whole world, and there are even more.

Essentially, Qiao Yu doesn't have any lofty sentiments.

But since he can live again, and he is very lucky to have a system, he can listen to the teachings from the future, so he shouldn't waste it in vain.

Qiao Yu didn't move his chopsticks, but Tan Zirui ate happily, like a little pig pushing the trough.

"What if I could make it?"

Tan Zirui obviously didn't take it seriously: "Then I'll call you Dad."

Qiao Yu looked him up and down, and felt that at such a young age, it was really a loss for him to have a son in his forties. At that time, it was not certain who would take care of whom.

That night, Professor Tan said he would not drink, but in the end he was given a lot of alcohol because he would not refuse.

On the contrary, it was Qiao Yu, as soon as the corners of his mouth curled up on his cheeks, the persuading people would automatically disperse, and he didn't dare to say much.

"I'm so stupid, really." Tan Zirui drank too much, and held on to Qiao Yu's hand, "I only knew that yellow and white people have a chance to have blue-eyed babies, but I didn't expect my daughter to talk to me directly." That's all right."

Under Tan Zirui's bitterness, Qiao Yu realized that the other party's willingness to return to the country had something else hidden.

Professor Tan's wife is also a university professor, and the two were classmates at the university. They got married on a blind date when they were [-], and later worked in the same research institute.

As a result, Kevin Tan's wife and boss teamed up to green him.

The PI of the research institute even said: "It doesn't matter if the child is your own, anyway, she always calls you daddy."

All in all, this incident caused quite a stir in the local academic circle.

……

……

As he spoke, Professor Tan was crying heartbroken on the wine table.

Qiao Yu couldn't help but voted 12 points of sympathy.

It's just that this also caused a problem. Professor Tan just drank too much, and didn't drink the fragments. When the two met the next day, they couldn't help being extremely embarrassed.

Qiao Yu raised two fingers and swore to the sky: "Don't worry, I won't say anything."

"..."

Tan Zirui walked away with a stinky face.

Since targeted drugs are to be developed, start-up funds must be indispensable.

It is very unlikely to ask the school for the start-up capital of several hundred million yuan.

The main reason is that for some schools, the government allocates only a few hundred million yuan a year, including subsidies for college students and graduate students; infrastructure maintenance; faculty salaries... With a bang, if you throw it all away for research, then the school doesn't have to open, sooner or later Mortgage to bank failure.

If public colleges and universities hadn’t received full support from the local government and the central government, after so many years of scientific research, it would be no problem to owe money and close down ten times.

And let the company bear the burden... Capable pharmaceutical companies have their own laboratories and scientific researchers, and they also cooperate with universities and research institutes around the world; Qiao Yu welcomes them, but it is impossible to give them fixed treatment all at once.

And for enterprises that are incapable, they can't even pay for their wages, so there is no money for research and development.

In this way, Qiao Yu finally had only one path left, and that was to apply for national scientific research projects.

National scientific research projects are reviewed and approved by the Huaguo Science and Technology Committee, and are usually divided into three categories.

The first category is major national scientific and technological projects, such as synthetic bovine insulin, two bombs and one satellite, and the moon landing plan, all of which fall into this category.It needs to be approved by the two courts, certified by the Science and Technology Committee, and then taken to the South China Sea for stamping.The application is the most difficult, and it is basically organized by the state.

The second category is a variety of national project plans, which are widely distributed in basic disciplines, high-tech and other fields, and are funds specially established by the state to promote scientific and technological development.Under normal circumstances, the laboratory application of colleges and universities has achieved outstanding results at this stage.

The third category is support for various humanities and art disciplines, including intangible cultural heritage, archaeology, and so on.

As a dragon soaring in the east, Huaguo is extremely short of money, but it is not without the money to squeeze out a billion to make targeted drugs.

If Qiao Yu was born 30 years earlier, with his current academic achievements, it would be no problem to apply for a class.

But it's 2018, not 1988.Even if you want to apply for public funds for the sake of the country and the people, you must first write a report with detailed data.

Qiao Yu intends to apply for a second-class project first, and get a scientific research funding of 4000 to [-] million.

In this case, at least the first phase of research and development will be completed, and there will be no problem.After the results are obtained, it is also convenient to absorb social investment and continue to ask for money from above.

At the beginning, Qiao Yu applied for 100 million in the school, and wrote 33 pages of application materials.Now the funding he applied for is not low, and the report will only be too much.

At least 100 pages or more.Among them, 100 pages are used to prove that he is not trying to cheat money.

After all, this is to be reviewed by the Science and Technology Committee.

When Tan Zirui found out that Qiao Yu was seriously writing the application report, he was really frightened.

After confirming again and again that Qiao Yu was not overheated, he deeply felt that the younger generation was scary.

At the same time, the 6 papers that Qiao Yu submitted at the beginning received responses one after another.

Two of them were passed directly, but the remaining four had different degrees of annotations, requiring supplementary data or minor revisions.

Qiao Yu felt that the only one working in the laboratory would be easy to lose fighting spirit, so he threw all the four papers to Tan Zirui.

Qiao Yu: "Help me change it."

Tan Zirui originally wanted to rise up in anger and say "why did you ask me to change your thesis", but Qiao Yu's next sentence made him swallow his complaint back.

Qiao Yu didn't even raise her head: "Write your name in the second paper."

Tan Zirui: "Okay."

With Qiao Yu's unremitting efforts, he spent two months in total, consulted countless materials, held three academic conferences, and invited Lin Feng and Ye Qinxue, who had retired long ago, to write the preface, and finally finished writing a 143-page project blue book.

"It stands to reason that this kind of thing is usually done by the scientific research dog under the professor..."

Qiao Yu saved the document, his expression suddenly full of confusion.

He also remembered a very important thing - tm is about to start school, where is my graduate student?

The author has something to say: Professor Qiao, miserable.Only when school started did I think of myself as a polished commander.