Back To The Age Of The '80s

"Sorry, sorry." David waved at Pete Smith without sincerity, and then pulled Li Zheng aside.

"Li, you are crazy!" The profit of carbapenem antibiotics is much higher than that of baminoxatin. He stretched his arms vigorously and drew a big circle in the air.

Li Zheng looked at David, who kept gesturing funny, and patted him on the shoulder, "Don't worry, I'm not short of such a patent." The tone seemed to say, I'm not short of such a dollar.

but!It's not a dollar!It is a patent worth tens of billions!

David looked Li Zheng up and down, as if looking at an alien.Glancing at Smith and the surprise on his affirmative face, he curled his lips and couldn't help asking again: "Are you serious? If you want, Roche can fully represent you in fighting for the rights and interests of carbapenem antibiotics."

"David Andorio!" Smith and Kent, who listened carefully to the conversation between Li Zheng and Li Zheng, felt their hearts aroused when they heard this. Smith strode towards the two without caring about cleaning up the residue on his clothes.

He gave David a hard look, and then turned to Li Zheng with a complicated expression, "Mr. Li Zheng, you mean to give up all rights and interests related to carbapenem antibiotics?"

When Li Zheng heard this, the corners of his mouth twitched slightly, "Mr. Smith, please correct me. What I mean is that I give up all possibility of obtaining commercial benefits from carbapenem antibiotics. But this does not mean that I give up the discovery of carbapenem antibiotics." One of those."

For Li Zheng, a former top scholar in the world, fame is much more important than money and interests.

"Of course! This is an indisputable fact!" Smith said loudly, he is not a scholar, he is just a businessman, and patents and profits are what he values ​​most.

Smith did not expect to achieve the purpose of his trip so smoothly. The tyrant of Merck did not hesitate to praise Li Zheng from the beginning to the end with the most beautiful words of praise, which made David dumbfounded. This is really true. In his impression, the arrogant Mr. Smith who is not allowed to enter? ?

This time, Smith ignored David's little gesture of winking. He took out a thick agreement from his bag with a smile on his face, "Mr. Li Zheng, according to what you Xiangjiang people say, your mouth will never be as good as your pen." Smith said strangely He dragged a sentence in Chinese in a strange way.

Li Zheng glanced over and saw that it was an agreement for him to voluntarily give up the patent rights of carbapenem antibiotics. There were two versions in English and traditional Chinese. It seemed that they came prepared.

Li Zheng smiled lightly, without procrastinating, took out a pen from his coat pocket, and signed his name neatly on the signature.

Smith smiled even wider. He made a gesture to accept the agreement, but Li Zheng put the agreement on the tea table with a smile and pressed it with a pen.

"I suddenly thought of something and wanted to discuss it with Mr. Smith." Li Zheng said.

Perhaps it is related to the contract template. There is an article in the agreement that marks the first batch of countries and regions where imipenem is planned to be launched, such as the United States, Canada, the United Kingdom, France, Italy, Xiangjiang, etc.

There is no Huaguo.

Only then did Li Zheng remember that imipenem was first launched in the world in 1985, but it was not until 2007 that Huaguo had the first imipenem cilastatin.

For 22 years, Li Zheng didn't know how many Chinese people would have to wait to die in despair because the drug imipenem was not available in China.

"Here, let's add Hua Guo." Li Zheng used a pen to add the word Hua Guo after Italy.

Smith and Kent looked at each other, Huaguo? The image of Huaguo in the 80s in the hearts of the people of the world is not so good, the country is closed and the economy is backward. In 1979, Premier Deng waved a cowboy hat while watching a rodeo in Houston, which was interpreted by the Western media as a sign that China was opening up and trying to integrate into the world.

A cowboy hat made the foreign media so excited, which also reflected from the side how closed and backward the image of Huaguo was in the Western world at that time.

"Although Huaguo has a large population, their demand for drugs is not large, and the price of imipenem is not cheap for them. I have no reason to persuade the business department to open up such a barren market." Smith Said embarrassingly.

Li Zheng shook his head, he pushed hard, and pushed the agreement in front of Smith and Kent, "Then I will give you a reason. I..." He pointed to himself, "I am from Huaguo. South approach to nephrotoxicity."

From the registration of core patents in 76 to the listing in 85, it took nine years.If Li Zheng's guess is correct, Merck's drug research team should be stuck on this bottleneck.

"You have a solution!" Kent slapped the table and stood up excitedly, "Okay, I promise! As long as the drug is approved for marketing, Huaguo will definitely be the first country to go on the market!"

Kent is the head of Merck's research laboratory, and at the same time has the title of vice president in charge of research and development. Although he generally doesn't care about things, he has the heaviest voice among the vice presidents.

Smith's eyes widened. He was about to speak, but was stared back by Kent. The president of Liushui is the head of the laboratory. As long as there are research results in his laboratory, he doesn't have to be afraid of Smith!

Li Zheng was right in guessing that the launch of imipenem was stuck in the clinical trials of the drug.Like the carbapenem antibiotics extracted by Li Zheng, imipenem has severe nephrotoxicity.Even because of this, two drug trial volunteers closed their eyes forever.

Over the past nine years, Merck Laboratories has been trying to alleviate nephrotoxicity. In recent years, it has gained some experience, but there is still a certain distance from the strict standards of the US FDA.

After hearing that Li Zheng had successfully extracted carbapenem antibiotics, Kent even had the idea of ​​bribing FDA personnel to hide the results of biological tests in order to speed up the marketing of imipenem.

Of course, it would be the best if imipenem can be successfully marketed through proper channels.

"I'm a little careful. Dean Chen will contact you for specific technical cooperation matters." Li Zheng said with a smile. He doesn't dispute the patent right of imipenem, but drug improvement technology is always worth a dollar.

On Friday night, Li Zheng's interview with the man of the century was broadcast simultaneously on the BBC worldwide.

Seeing the young man speaking with his eyes lowered in the TV program, the indignant Xiangjiang people gradually calmed down from the excitement aroused by the "Three Questions" of Xiangjiang Daily.

After the anger calmed down, the rationality slowly returned.

In this drug-resistant strain infection incident, the success of Queen Mary Hospital was praised even by the foreign media, but why did their own newspapers in Xiangjiang overwhelmingly write about the six patients who died of infection?

"The risk of clinical use of unmarketed drugs, the pressure behind this miracle!"

"The character of the century, a game of life and morality!"

"Trust, the best medicine for conflicts between doctors and patients!"

On the second day, public opinion in almost the entire Xiangjiang River was reversed.

"This Li Zheng's influence is really great. Lao Wang called last night. All the pages that were originally prepared were reprinted. The printing factory worked an extra 12 hours of night shift, and the newspaper almost opened the skylight in the morning." Shen Wannian said while Put a sliced ​​steak in your mouth.

"Jingla" The ear-piercing noise of pouring tea and rubbing against porcelain resounded in the empty dining room.Yang Wanru frowned tightly, and looked at Zhao Qiuhua unkindly.

Zhao Qiuhua raised his head slightly, his eyes passed through Yang Wanru, and placed his eyes on the TV screen not far away.On the TV screen, that familiar face had a calmness and confidence she was not familiar with.

"I'm full." Zhao Qiuhua suddenly put down the knife and fork, and the sound of the metal colliding with the tableware was clear and powerful.

Shen Hongji glanced at half of the steak left on Zhao Qiuhua's plate, and said gently: "Eat some more, or if you like Chinese food, let Auntie Liu do it."

Zhao Qiuhua shook his head, didn't say much, nodded to Shen Wannian and Yang Wanru, picked up the coat on the chair and walked out.

Shen Hongji smiled wryly, put down the tableware in his hand, and stood up.

"Mom and Dad, I'm full too." After speaking, he took his coat and quickly chased him out.

Yang Wanru panicked, "I'm so pissed off! Sure enough, I'm from a small place. Marrying such an uneducated daughter-in-law is really a crime for me!"

Shen Wannian glanced at her coldly, "When eating, don't talk much."

Yang Wanru froze, her eyes swept over her daughter who was eating with her head down and the two empty plates, her dissatisfaction with Zhao Qiuhua reached its peak.

"Qiuhua, didn't you feel good just now? Why did you get angry again? I know Mom has a bad temper, but this time..." Shen Hongji was full of helplessness.

Shen Hongji and Zhao Qiuhua are college classmates who met in romantic France.At that time, Zhao Qiuhua was bright, full of confidence and vitality. She actively participated in club activities, attended gatherings of overseas Chinese students, and participated in the feminist movement.While the rest of the people were still stumbling in French, Zhao Qiuhua had proficiently mastered English, French, German, and even a little Italian. In the heart of the introverted Shen Hongji at that time, Zhao Qiuhua was like a goddess.

Shen Hongji had been secretly in love with Zhao Qiuhua for two years, and with the encouragement of his roommate, he mustered up the courage to confess his love to the goddess, and Zhao Qiuhua agreed immediately.It was only later that Zhao Qiuhua told him that she had been following him for a long time.Campus love, two-way secret love, the two people's college romance is passionate and sincere.

But the happy time always flies very fast. Four years passed in a hurry. One of the two wanted to return to Huajing, and the other wanted to return to Xiangjiang.The two made an appointment to talk on the phone as soon as they got home and declare their love to their parents.

However, Shen Hongji never waited for this call. Later, Huaguo was in political turmoil, Xiangjiang and Huaguo were completely cut off, and the two broke off contact.

Until a year ago, when the two met again, Shen Hongji ended his nominal marriage without hesitation, and despite Yang Wanru's strong objection, he insisted on obtaining a marriage certificate with Zhao Qiuhua.