Back To The Age Of The '80s

"I'm old, I'm really old, but after two or three days, this head doesn't seem to be my own." Su Changzhi stretched his waist, and put the last tube of antibiotic extract into the incubator.

In the past few days, the professors of Xiangjiang University School of Medicine headed by Su Changzhi have completely put down their work, soaked in the laboratory with Li Zheng, ate some bread when they were hungry, and leaned against the table for a while when they were sleepy. Together, two hundred carbapenem antibiotics were sent to Queen Mary Hospital.

"Professor Xu called just now. He is completely out of danger, and his wound is recovering well. If there is no accident, he will be discharged from the hospital in a week." Li Zheng announced the good news to everyone with a smile.

All the professors were really happy.

"Good Xu Mingsheng, when he is discharged from the hospital, we must have a good meal at his house, I am an old man with old arms and legs." An old professor said while pressing his shoulder, which caused a burst of laughter in the laboratory Voice.

There were laughter and laughter in Qingyuan, but it was another scene in the hospital.

As of last night, Queen Mary Hospital had confirmed 87 infected people, 78 of whom were injected with carbapenem antibiotics, passed the critical period successfully, and have been sent back to the general ward.

But the remaining nine people were either old or suffering from other serious diseases with extremely weak resistance.Experts at Queen Mary Hospital have assessed that the probability of these people being able to survive antibiotic nephrotoxicity is less than 20.00%.

"Patients in beds 18 and 24 have shown signs of organ failure. The condition of the remaining seven patients is not very good. Drug-resistant bacterial infections have caused various complications. I think we need to vote collectively on whether to inject antibiotics." In the conference room, Chen Xuhua said in a deep voice.

"Without medication, the patient's death is a drug-resistant bacterial infection. The hospital is not responsible for normal medical risks. If the patient is treated with medication and the patient dies of drug toxicity, it is a medical malpractice. We are doctors, but we are not saints." The middle-aged doctor said.

There were rustling discussions in the conference room, Chen Sufen pursed her lips and remained silent, while Chen Xuhua had a wry smile on her face.

"Then let's vote." Chen Xuhua patted the table, "Those who agree with the injection raise their hands."

The conference room was very quiet, everyone looked at me and I looked at you, and none of them raised their hands.

"Then let me ask the question in a different way, raise your hand if you agree with not injecting!"

There was another silence, and a few minutes later, one hand was raised up alone, and then it was as if the play button was pressed in a movie, and one hand after another was raised.

In the end, except for Chen Xuhua and Chen Sufen who did not express their views, almost all doctors opposed injecting carbapenem antibiotics to the remaining nine patients.

Chen Xuhua's heart was indescribably complicated, he felt ashamed but at the same time he breathed a sigh of relief.

"Since this is the case, everyone should do a good job of explaining and appeasing."

"According to our station, last Wednesday, Queen Mary Hospital announced a large-scale outbreak of Pseudomonas aeruginosa infection in the hospital. The number of people infected this time was 92, of which 78 were successfully out of danger, 5 died, and the remaining 8 people were still alive. Efforts are being made to rescue. This drug-resistant bacterial infection is violent and widespread, and it is very rare in the world. According to the hospital's explanation, it is mainly the result of the overuse of antibiotics. At the same time, the reporter learned from relevant medical practitioners As we all know, in the case of large-scale Pseudomonas aeruginosa infection, the global average survival rate is less than 12%, but Queen Mary Hospital achieved 84.8%, which is a miracle!"

"BBC's topic on antibiotic abuse, the British textbooks will put the Queen Mary Hospital incident in the British medical school textbooks!"

"The suspension of the Faculty of Medicine of Hong Kong University is actually related to the incident of Mary's patina fake!"

"Another Einstein, the inventor of the original drug discovered a new antibiotic again!"

The reputation of Li Zheng and Li Zheng's laboratory reached its peak after the insider of Queen Mary Hospital accidentally leaked the word.

"Li Zheng, if this goes on like this, you will have to raise wages for the security guards. I thought that only Xiangjiang paparazzi could get in, but I didn't expect those reporters from daily and evening newspapers to climb over the wall." Zheng Lingling said while tidying up the experimental table. .

Li Zheng also had a helpless look on his face. He thought that he had accomplished much more in his previous life than he does now. At that time, he never saw reporters blocking the door of his laboratory.

"By the way, don't you register the patent first this time? To save you from suffering like last time."

Li Zheng shook his head.

"This is still a half-finished product."

Of course, this is just Li Zheng's excuse. Although carbapenem antibiotics failed the biological test and the drug is still very toxic, the 84.8% survival rate at Queen Mary Hospital can fully explain the practicability of the drug.The molecular structure of the drug is also stable enough to apply for a core patent.

But Li Zheng knew that at this time, Merck of the United States, also known as Merck, had already registered the core patent of carbapenem antibiotics. Because it involved new drugs that had not been marketed, the patent was still in the confidential stage.

If Li Zheng wanted to get a share of the pie, it would not be difficult. After all, Merck’s imipenem was only launched globally in 1985. With Li Zheng’s foresight, he bypassed the core patents and preemptively registered imipenem’s generic drug at all. difficulty.

But he didn't intend to.As the pride of being a top scholar in the world, he is not allowed to do so.

It's just that he thinks so, others don't.

The pursuit of life and health has no borders. The news that the survival rate of Pseudomonas aeruginosa infection in Hong Kong Mary Hospital was as high as 84.8% quickly spread to the United States across the ocean.

The United States considers itself to be the country with the most developed medical level, but seeing this miraculous report, even the best experts in the United States are also dumbfounded.

"The Xiangjiang people must have developed a new antibiotic! God, the antibiotic for Pseudomonas aeruginosa! This is a milestone in the history of antibiotics."

Merck headquarters in the United States.

Mr. Smith, the president, slammed the New York Journal on his subordinates.

"[-] million US dollars, a total of [-] million US dollars, not including the investment in laboratory construction and equipment! Why are you not as good as an underage child!"

"Mr. Smith, imipenem has reached the stage of biological testing, and its effect is very good. After reading the New York Daily, we called the patent offices of various countries immediately. The biologist named Li Zheng did not Register the patent of carbapenem antibiotics." Mr. Brown kept wiping the fine beads of sweat on his forehead.

Imipenem is a key project of Merck, and the first phase of core patent registration was completed seven years ago. However, in the past seven years, the progress of drug trials has been slow, and the drug has not been on the market for a long time.Seeing that the dawn was just ahead, something like Li Zheng happened.It's like a 3000-meter long-distance race. It's almost the finish line, but No.1 is already waiting for him at the finish line.This kind of aggrieved feeling is really uncomfortable.

What's more, Merck has invested nearly one billion US dollars in the project of imipenem. In the past nine years, if Li Zheng's drug is really on the market first, their losses will be immeasurable.

"Maybe that scholar doesn't intend to register for a patent..." Mr. Brown's voice was a little weak.

Smith's cup was slammed to the ground, "Aris Brown, when did you learn to place your hope on others. Merck doesn't need such a weak person!"

"Mr. Kent, please come here. I have something to discuss with him. Also, let the secretary's office contact Li Zheng's laboratory. I think I need to talk to that genius in person." Smith rubbed his temples and said.

Brown nodded repeatedly and quickly walked out of Mr. Smith's office.

A week later, Smith and Kent got on the plane to Xiangjiang, and the British BBC People of the Century program officially sent an interview invitation letter to Li Zheng's laboratory. It was announced that the rescue was invalid and died. The three survived with strong willpower, but they left lifelong sequelae.

"Teacher, congratulations on being discharged from the hospital!" Holding a bouquet of carnations, Li Zheng, along with a group of professors from Xiangjiang University, came to pick up Xu Mingsheng from the hospital.

Xu Mingsheng's injury is recovering well. After the operation on his leg, although he still can't move freely, he can walk with a cane for a while every day.

"Hahaha, this is the first time I've received flowers in my long life! Li Zheng, this time I'm really thankful to you. You are my savior!" Xu Mingsheng was supported by Chen Sufen and sat in a wheelchair.

"Teacher, you are too serious. You have already made a good start on this topic, and I am just following your train of thought."

Xu Mingsheng waved his hand, "Don't embarrass me, thinking... If sorting out materials is also thinking, those of my subordinates who have studied first and second can already take charge of their own."

Professor Wang laughed loudly, "Old Xu, you should thank Li Zheng, otherwise, your funds would have been split up by these old fellows."

Xu Mingsheng raised his eyes when he heard the words, "Go, go! Don't think about my funding!"

There was laughter in the ward, and while everyone was talking and laughing, suddenly a burst of sorrow came from outside the window.Crying, shouting and cursing sounded together.

"What's going on outside?" Xu Mingsheng asked, frowning.

Chen Sufen poked her head out to take a look, the expression on her face suddenly froze.

I saw rows of wreaths blocking the entrance of the entire hospital at the entrance of Mary Hospital, and several family members of the patients stood in the center of the entrance holding the patient's posthumous photo.

They shouted loudly: "Mary Hospital treats people's lives recklessly and does not give medicines!"

The sound of neat slogans accompanied the crying of the woman and child, which attracted the attention of passers-by.

"Old Xu, you chat with them, I'll go out first." Chen Sufen forced a smile and said.

Xu Mingsheng patted her hand, "Go, don't worry about me."