Back To The Age Of The '80s

"Xiangjiang is a big international city. Because of the relatively loose policy in the past two years, many friends from Vietnam, Laos, and Indonesia came here. In the past ten years, the number of sick babies received by Xiangjiang Orphanage has increased sharply, and many of them Young children suffer from cryocytosis."

Xu Mingsheng sighed at this point, "Two days ago, we were invited to attend a seminar at Queen Mary Hospital, and we had a lot of feelings. Such soft little children, their lives have entered the countdown before they even started. , Seeing these children lying motionless on the hospital bed, I really feel that we are not doing enough!"

"So, I discussed with Professor Wang and Professor Zhao, and I plan to make an appeal at the meeting. I hope everyone can pay attention to this special disease and special medicine."

"The following are some materials collected by Xiao Zhang. Let's talk about your opinions."

Li Zheng continued to scroll back. After the introduction about frozen blood disease, there are some photos of sick infants and young children. Their skin is blue, and their limbs and torso are arched into a strange arc due to atrophy. Xu found that the camera was taking pictures of them. The children and their bodies The extremely uncoordinated big head turned to look at the camera, and there was no hope for life in the big eyes.

Li Zheng's heart trembled.

Indeed, he did not do enough.How long has it been since I remembered my original intention of switching from molecular biology to pharmaceuticals?Li Zheng's fingertips brushed across the child's eyes, his eyelids drooped so that no one could see his expression.

"Li Zheng, tell me what you think." Xu Mingsheng called Li Zheng's name.

Li Zheng put down the documents in his hand and said: "Frozen blood syndrome is different from ALS. It is essentially a blood disease. The coagulation molecules in the blood increase abnormally, which leads to an increase in blood density and gradually coagulates. According to the existing medical methods, Forcibly inhibiting the differentiation of blood coagulation molecules with amisatin is fatal to infants under the age of two."

"The biggest obstacle to the development of this drug is the clinical four-drug trial. How to find so many sick babies to participate in the trial. Even if they are found, the babies themselves cannot sign a voluntary agreement for drug trials. The institution that developed this drug, in a It will take great public opinion and political risks at the beginning. This appeal is not convincing enough."

Li Zheng's words were calm and cruel.Extremely low market expectations, great public opinion and political risks will be labeled as immoral and human experiments at any time. In the face of these realistic conditions, this appeal seems a bit weak.

Li Zheng's words were too sharp and realistic, and the office suddenly fell silent.

Professor Zhao patted Li Zheng on the shoulder, "The existing problems are difficult to overcome, and we can only do what we can."

After leaving Xu Mingsheng's office, Li Zheng didn't go back to the classroom or the hotel, but went to Jingyuan.

The current Jingyuan should be called Qingyuan, because the Jingyuan's Jingyuan is Shen Hongjing's Qingyuan.The land was in Li Zheng's hands, so the name was naturally inappropriate.

But Li Zheng didn't want to spend time thinking about the name, so he directly removed the cursive initials on Jing and changed his name to Qingyuan.

The engineering team sent by the Liang family moved very quickly. The exterior walls of the five villas have been pasted with stones, and the green garden is surrounded by high iron fences. The security company sent people to be on duty 24 hours a day, so the safety is extremely high. .

"How long will it take to finish?" Li Zheng asked.

The contractor smiled and said, "Young boss, don't worry. Butler Fang said that your equipment will arrive in one and a half months. We promise to tidy up this place before your equipment arrives!"

a month and a half...

He can't wait a day!

Li Zheng called Zhou Sitian and told him that he was going to attend an international conference in Tokyo in a few days, and immediately got into the laboratory.

Li Zheng asked Xu Mingsheng to borrow this laboratory. Not only did he borrow the laboratory, he also borrowed two graduate students to help him, one of whom was the male academic bully whom he met this morning.

The male Xueba was also surprised to see Li Zheng.At noon today, he suddenly received a call from Dean Xu, asking him and his junior to go to the laboratory to help.

Zhang Yuejun is naturally very happy to have this opportunity.Laboratories are the same as enterprises in society, and the class divisions inside are very clear.At the top of the hierarchy is the head of the laboratory, that is, Xu Mingsheng, the actual owner of the laboratory, followed by several associate professor-level researchers. They can often independently host a project and have a lot of autonomy.

Then there are researchers who cannot independently host projects. Among them are associate professors with less qualifications, and there are also lecturers who are trying to climb up to the position of associate professor.In the end, it's their postgraduate experiment dogs.

And the experimental dogs are also divided into three, six, and nine grades. The first-class experimental dogs can participate in a little bit of project research. If the project host is happy, they can let you do it in every corner. It has gold content.

Second-class experimental dogs, commonly known as odd jobs, can touch experimental equipment, and can perform some simple experimental operations at the request of the project host or first-class experimental dogs. Generally, it is repetitive labor. Whether you can mix it up depends on the project. Moderator's mood.

Don't mention the third-class experimental dogs, look for information, look for information, or look for information.What can be fought for is the position of four works and five works. To put it mildly, there is actually no gold content.

Zhang Yuejun is considered a first-class experimental dog, otherwise it would not be his turn to participate in the Asian Biopharmaceutical Conference.And his junior Liu Menglin is a second-class experimental dog, already in the second grade of research, mixed with two second authors, one is the second author of SCI papers, and the other is the second author of ordinary papers. From the perspective of later generations, this result can be described as miserable, but in the 80s, Already considered good.

But Zhang Yuejun did not expect that he waited all afternoon, and what he waited for was not Professor XX, but Li Zheng.

A freshman?

Are you fucking kidding me? !Zhang Yuejun couldn't help scolding his mother in his heart.

Li Zheng naturally saw what Zhang Yuejun and Liu Menglin were thinking. He walked into the laboratory, put on shoe covers, took off his coat and hung it on a hanger, put on a white laboratory coat, washed his hands, and put on rubber gloves, all in one go.

After putting on the familiar equipment, Li Zheng felt refreshed for a while. He stretched his neck, then turned around and said to Zhang and Liu, "Let me introduce myself, my name is Li Zheng. A month and a half ago I published a paper on 'Drug Catalyst' on "Microbology". The patent money paid by the company bought Jingyuan, ten kilometers away from Xiangjiang University, and used it as the land for its own laboratory construction.”

Li Zheng listed his deeds in such a high-profile way, not for showing off.It's that he understands the difference between a reluctant lab dog and a motivated one.

Although the lab dogs do some tedious chores and mindless repetitive work, it is undeniable that they save a lot of time for the project host.In a laboratory, laboratory dogs are indispensable, this is a recognized fact.

Zhang and Liu have big mouths, is it true or not?A freshman...

"Whether what I said is true, you can ask Professor Xu for verification. Senior Zhang, you should know something about the project I am going to do now. We are short on time. I hope that the two seniors can try their best to help me. I promise to give you two The position of the second author." Li Zheng paused, "The second author of a weighty SCI paper."

Zhang and Liu were speechless, they knew that what Li Zheng said should be true, and Xu Mingsheng was their mentor, no one would tell such a lie that could be easily debunked.Zhang Yuejun and Liu Menglin looked at Li Zheng, then at themselves, and suddenly felt that they had been living on dogs for so many years.

"Hey, wait, Li Zheng, I don't know how to address you, can I just call you by your name? You said I know the project, what project? I don't seem to know too much." Zhang Yuejun scratched his head, looking confused.

Li Zheng was dumbfounded. He took off a rubber glove, and took out the materials about "frozen blood syndrome" that morning from his bag.

"Seniors can just call me by my name directly. This is the data on 'frozen blood syndrome'. Professor Xu said that you collected it."

"Um, yes." Zhang Yuejun nodded.

"That's it. The conference will be held on the 31st, and we will leave on the 30th. There are still less than five days left. I plan to do some preliminary work on the research of cryocytosis drugs." Li Zheng lowered his head and put on his gloves again.

Zhang Yuejun's expression was dull, and Liu Menglin was obviously still a little confused about the situation. He picked up the materials and flipped through them, and then stared at Li Zheng with disbelief.

Just kidding!

According to a data provided by the Tufts Drug Development Research Center, the average cost of developing a new drug is about 26 billion US dollars, and the average research and development period is 7-11 years.

You saw an information this morning and told me at noon that you are going to research new drugs? ?

Li Zheng saw the suspicion in their eyes and rubbed his temples. He began to miss his research team.

"Frozen blood disease is caused by an abnormal increase in coagulation molecules. There is already amexatin on the market that can be used to treat this condition, but it is not suitable for infants and young children under the age of two. But this at least shows that ammonia The ingredients of sardine can be used as a reference for the research and development of cryocytosis drugs, and our experiment is not clueless." Li Zheng explained patiently.

Seeing that the two still couldn't believe it, he coughed dryly, "Of course, I won't ask the two seniors to help me in vain, except for the second work I promised. When you help me in the laboratory, you can use it as the time limit." Calculated by the hour, ten Xiangjiang coins per hour."

The average monthly salary in Xiangjiang is only 1000 yuan in the 80s, which is already a very high salary level.

Zhang Yuejun and Liu Menglin's eyes lit up, and they looked at each other, "This is so embarrassing. Professor Xu asked us to help you."

Li Zheng smiled, "Get paid according to your work, there is nothing to be ashamed of. I promise, this is a little secret between us. Professor Xu will not know."

When Zhang Yuejun and Liu Menglin heard the words, the smiles on their faces were much more real.Regardless of whether he is daydreaming or not, they have the money to take it, and if they really let him successfully develop a new drug, they can also make a second job, a business that is sure to make money without losing money.

So the two immediately said: "If you have anything to do, just ask, we will do our best to help."

Li Zheng nodded with a smile, and immediately entered the working state.

"Liu Menglin, before five o'clock this afternoon, bring all the materials of amethadin to the laboratory, especially the report of its drug trial stage, find it!"

"Zhang Yuejun, repeat the production process of amixatin, record each step, increase or decrease ingredients, and observe its reaction with hemagglutinin!"

"it is good."

"it is good."

As expected of experienced experimental dogs, they quickly started to operate with Li Zheng's command.

The author has something to say: It involves some professional, in line with the principle of rigor, I bombarded my friends, Calvin... so it is a bit short, tomorrow weekend, thick and long! !

The disease in this article does have a prototype, but I have done artistic processing, so there is no need to check the number.There are also drug names and disease names, which have also been processed~