Siheyuan: Rebirth in a prosperous era, great doctors are sincere

Chapter 346 Purification of Oxytetracycline (Page 12)

In recent years, domestic antibiotic research has developed rapidly, and its role has gradually become more prominent, and superiors have attached great importance to it.

The Antibiotics Department was separated from the Institute of Biology of the Ministry of Health and established as an independent research institute.

The Antibiotic Research Institute is developing rapidly. Especially this year, many overseas students have been recruited, and its strength has been greatly enhanced.

At the beginning of the year, the first international antibiotic conference was held in Poland.

Although it is an international conference, the participants are all Guo Jia from the same camp. Except for our country, the participants are all Guo Jia who later joined Huayue.

After the meeting.

Comrades from the Institute of Antibiotics received oxytetracycline strains donated by Polish biochemists.

After returning to China, the comrades from the Antibiotic Research Institute produced oxytetracycline in just three or four months.

Oxytetracycline is an organic substance with the chemical formula C22H24N2O9. It is a light yellow crystalline powder, slightly soluble in ethanol and very slightly soluble in water.

It has strong antibacterial activity against Streptococcus pneumoniae, Streptococcus pyogenes, meningitis, Escherichia coli, Aerobacillus aerogenes, Shigella, Yersinia, Listeria, etc.

At that time, the Ministry of Health and several of its major agencies were located on the Beiheyan'er side of Houhai, and the Antibiotic Research Institute was not too far from the Sixth Hospital.

Oxytetracycline has broad-spectrum anti-pathogenic microorganism effects and is a rapid bacteriostatic agent. It has a bactericidal effect on certain bacteria at high concentrations.

There was a dance party at the Institute of Microbiology on the weekends. Researcher Wang invited Ran Qian to go there several times. The relationship between the two of them flourished. Both parties lost their parents, and they actually discussed getting married.

In addition, oxytetracycline also has strong effects on rickettsiae, mycoplasma, chlamydia, actinomycetes, etc.

He came into contact with ethyl acetate when making penicillin, which is now available in the laboratory of the Sixth Hospital, but Li Ping'an could not tell Ran Qian directly.

Ran Qian had discussed it with her brother and sister-in-law.

Li Ping'an thanked: "Thank you very much!"

Ran Qian and Li Ping'an talked about some situations at the Antibiotic Research Institute and said that they were thinking of ways to purify oxytetracycline.

This old friend, whose surname is Wang, works as a researcher at the Antibiotic Research Institute.

After Ran Qian got married, she went to work normally, which had little impact on colleagues like Li Ping'an. At most, she often went to the Antibiotic Research Institute to attend dance parties on weekends, and sometimes she would come a little later when she went to work on Mondays.

He already had an idea for purifying oxytetracycline and did not need any other special help.

Before the solution, Ran Qian came back from the United States to work at Union Medical College Hospital, while Researcher Wang stayed to continue studying for a master's and doctoral degree in microbiology.

After receiving the certificate, the two of them would be considered married after having a meal at Ran's house.

At their age, it would be nice to meet someone who is pleasing to each other and can accept each other.

"Safe!" Ran Qian said: "Our laboratory is very good. Sometimes you can go to the laboratory and try to see if you can find a method to purify oxytetracycline. I know you have connections with the Medical University. , you can exchange information with them, and let me tell you good news. If you really need a certain solvent, I can also go to the Antibiotic Research Institute to help you ask."

It is stable in the air and becomes darker when exposed to light.

He didn't expect that it would be difficult to come back after the liberation. He had been stranded there for several years and just returned to China this year.

Researcher Wang has no one in his family anymore. He had received a scholarship from the old government to study in the United States, and he was alone. He said that if he married Ran Qian, he could marry her.

After oxytetracycline was produced, clinical trials were conducted at Beijing Medical University. It was found that this drug was very effective in treating certain types of pneumonia, and no allergic patients were even found clinically.

Oxytetracycline has been mass produced and used in clinical applications.

Researcher Wang and Ran Qian were classmates when they were in the United States. Both of them were studying medicine.

just.

Li Ping'an knew that oxytetracycline in later generations was generally purified through chromatography technology, but this technology is not available now, but it is not impossible to purify it. After dissolving, extracting, and crystallizing with ethyl acetate, a product with higher purity can be obtained. Although the high-grade oxytetracycline is not comparable to the oxytetracycline of later generations, its purity is also quite high.

but.

What a coincidence.

Li Ping'an only found out about it when she told her colleagues about it after she got married.

The two chatted happily, and the more they talked, the more speculative they became. They learned that the other party was both in their thirties and had not yet been married, and both wanted to develop further.

in fact.

Reunion.

After that, Ran Qian moved to the Antibiotic Research Institute.

The two of them just danced a few times, so it's not entirely certain that they have a deep relationship. There must be a vague good feeling, and there may also be love, but it's not too deep.

After marriage.

How could Li Ping'an say this at any time when even the Antibiotic Research Institute was researching a technology?

If necessary, Li Ping'an can also go to the Drug Research Institute for help, where they have closer contact with their superiors.

Oxytetracycline is a broad-spectrum antibiotic. Due to technical reasons, it can only be extracted from the fermentation broth of oxytetracycline at this time. Moreover, due to purity issues, it can only be made into oxytetracycline tablets but not injections.

At that time, neither domestic nor international people knew much about rickettsiae, mycoplasma, chlamydia, actinomycetes, etc., but oxytetracycline was regarded as a drug that can treat pneumonia.

On the weekend, Ran Qian met an old friend of hers when she went to the Lotus Market.

Oxytetracycline is a newly developed antibiotic and has not developed resistance. If it can be further purified, the effect will be even more significant.

soon.

This is meant to arouse suspicion.

Ran Qian has never performed surgery except for working as an assistant to Li Ping'an a few times, and her work focuses on management.

Also, the director doesn’t often perform surgeries.

Ran Qian reported to the superiors that the Sixth Hospital needed to recruit a new group of doctors.

After the hospital expanded into a general hospital, although a group of doctors were assigned, it was not enough, especially in the surgery department. The director and Ran Qian did not do much surgery. Zeng Jia was about to leave after studying in the Sixth Hospital for a while. The surgeon was indeed too good. not enough.

just now.

The hardware facilities of the Sixth Hospital have kept up, and the nursing school continues to provide nurses. If more doctors are added, it will better serve more patients.

There's a new person coming to the Department of Surgery.

Li Pingan had an indifferent attitude.

Anyway, even if a few more doctors are called in, he won't be left without surgery.

Zeng Jia was not under any pressure. He just came to the Sixth Hospital to study, and he might be transferred back to work in the northwest.

Wu Ze and Jiang Daqiao felt some pressure.

The new doctors will definitely compete with them. If more operations are performed, they will do less.

Jiang Daqiao felt more pressure than Wu Ze.

At this time, Wu Ze has not yet recovered from the impact of the last time he performed a fatal surgery. Not many people came to him for surgery. Even if he loses some patients, how much more can he lose?

Tap the screen to use advanced tools Tip: You can use left and right keyboard keys to browse between chapters.

You'll Also Like