Siheyuan: Rebirth in a prosperous era, great doctors are sincere

Li Ping'an went directly to the Pharmaceutical Research Institute to explain the manufacturing method of nalidixic acid.

Comrades from the Institute of Drug Research take this matter very seriously.

There are only a few types of antibiotics currently available.

Penicillin and streptomycin are only effective against Gram-positive bacteria, and sulfa drugs have serious side effects.

After finally discovering an antibiotic against Gram-negative bacteria, how can we not pay attention to it?

Li Ping'an synthesized nalidixic acid with relevant staff in the laboratory of the Institute of Drug Research and conducted drug susceptibility tests.

The drug susceptibility test is a test of the drug susceptibility of bacteria. The results showed that nalidixic acid is effective against Escherichia coli, Klebsiella, Proteus, Shigella, Salmonella, Enterobacter and Haemophilus influenzae. Some strains have antibacterial activity and are also active against Neisseria gonorrhoeae, but they have no antibacterial activity against Gram-positive cocci such as Pseudomonas, Acinetobacter and Staphylococcus.

originally.

Li Ping'an also wanted the staff to test whether it could be effective against blood-sucking worms, but he ran into trouble. The drug research institute at that time did not have blood-sucking worm pathogens, mainly because there were no drugs that could restrain blood-sucking worms at home and abroad. , the Institute of Drug Research also did not collect it.

There is no need to wait for clinical trial results to come out. Mass production can actually be carried out once the drug susceptibility test results are available.

Li Ping'an proposed to produce nalidixic acid at the Beijing Pharmaceutical Factory first, and then proceed to large-scale production after the clinical trial results are available.

The comrades from the Drug Research Institute naturally agreed.

Kong Bohua was also at the Institute of Drug Research. He originally studied Suxiao Jiuxin Pills with Liu Yuyi and others. He was very happy to learn that Li Pingan had newly synthesized an antibiotic in the laboratory. After asking him in detail, he said to him: "As long as there is no shortage of various raw materials for synthesizing nalidixic acid, the superiors will quickly mobilize them and prepare everything at the same time!"

The synthesis of nalidixic acid does not require special equipment, and is simpler than the equipment for producing penicillin and streptomycin. It is easy to get these equipment together.

The existing equipment of the Jingcheng Pharmaceutical Factory can produce it, and there is no need to add new equipment.

Li Pingan was naturally very happy.

Early Days.

Schistosomiasis has always been a major infectious disease, not to mention that there are floods in the middle and lower reaches of the Yangtze River. It is necessary to produce nalidixic acid as soon as possible and prepare reserves.

Spring passed.

Enter summer.

The weather is getting hotter.

Because of the rain, it was much cooler than in previous years.

There are more and more vendors in the Lotus Market, and some are selling summer-specific foods such as ice bowls.

The Li family started using electric fans again.

The electricity bill has not increased much. Each fan costs an additional 60,000 yuan per month.

Grain production in the middle and lower reaches of the Yangtze River has decreased, but fortunately the production in the north has not decreased much. Grain prices in the capital are still stable, with only a slight increase.

The price of food on the black market follows the market.

When the market price fluctuated slightly, the performance on the black market was particularly obvious. It increased by almost one-third. The price was almost twice the price in the grain store, which was more than 4,000 yuan per kilogram of flour.

Jia Dongxu couldn't bear it, but he had no choice but to bite the bullet and continue buying food on the black market.

Liu Yue is about to give birth to a baby, and nothing can go wrong at this time.

Her food intake cannot be reduced, and her food standards cannot be lowered, otherwise she will cause trouble!

Everything is ready.

Jingcheng Pharmaceutical Factory began to produce nalidixic acid, and began clinical production in many hospitals such as the Sixth Hospital and Jingcheng Medical University Hospital.

This drug is mainly used to fight intestinal diseases. Of course, it can also be used to treat gonorrhea. However, in the early days of the founding of the People's Republic of China, several hospitals were banned. After three or four years of control, not many people in the capital suffered from this disease.

Li Pingan was thinking about how to find a patient with schistosomiasis to test the efficacy of nalidixic acid.

pity.

Patients with this disease are not easy to find.

at that time.

It's okay if schistosomiasis is in the incubation period, but once an acute attack occurs, the mortality rate can reach 70% or even higher. It is definitely a serious infectious disease and very difficult to deal with.

Li Ping'an thought to himself that he hoped he would never encounter this disease.

When the folks from Qinjiatun and their cooperative went to the city to see a doctor, they were introduced to the Suzhou Red Cross Hospital by Li Ping'an. This hospital is a public welfare hospital. The doctor's salary is paid by the Suzhou Red Cross Society and the Ministry of Health, and the surgical and hospitalization fees are fully paid. Free, you only need to pay for medical expenses. It can be said that you can't make much money at all, it's just enough to survive. The villagers can get a lot of benefits.

The neighbors of the courtyard house saw this in their eyes and remembered it in their hearts. As long as the workers at the steel mill were not seeking medical treatment, their family members would all go to the Suguo Red Cross Hospital.

Even if the steel mill medical clinic offers discounts to workers' families, the discounts are incomparable to those of the Soviet Union Red Cross Hospital, especially for surgeries, where the discounts are even greater.

Liu Yue went to the obstetrics and gynecology department of Su Guo Red Cross Hospital to wait for delivery when she was about ten days away from her due date. Anyway, she didn't have to pay hospitalization fees, so she could stay a few more days.

Dr. Su Guo actually agreed that Liu Yue should be hospitalized in advance. It was not that Liu Yue had any privileges, but because she was too fat. She needed necessary prenatal care and a diet. Although it was a little late to start the diet at this time, But it’s better than walking all the way to the dark side!

The gynecologist who treated her believed that Liu Yue would most likely need a cesarean section. Jia Zhang claimed that her daughter-in-law might be pregnant with twins, but the doctor did not think so. The probability of twins was too small, and it was not so easy to give up. Liu Yue met.

The doctor asked Liu Yue to be more restrained, but Jia Zhang and Liu Yue were not happy. If the translator hadn't threatened them that Liu Yue would not be allowed to give birth in this hospital if she didn't diet, they might not have been obedient.

Jia Dongxu also took leave on the day Liu Yue gave birth, and she and her mother Jia Zhang waited outside the delivery room.

result.

no doubt.

Liu Yue had a difficult delivery.

Natural delivery was not possible, so a cesarean section was naturally necessary. Dr. Su Guo found a translator to discuss with Mrs. Jia Zhang and her son. Mrs. Jia Zhang actually licked her face and asked if the children had been born and if they were twins.

The translator already knew what was going on in the delivery room, and without waiting for the doctor to speak, he sneered and said: "The baby in the mother's belly is so big, and she still wants twins? Is there a place to put them? You guys should make up your mind quickly. If you don't do the operation as soon as possible, don't you?" When it comes to the child in a pregnant woman’s belly, the life of the pregnant woman may be in danger too!”

The translation is not to scare them.

The infant mortality rate at birth was very high at that time. Generally speaking, midwives were required to deliver babies. In cases of dystocia or postpartum hemorrhage, it was basically impossible to save the baby. It was good to save the pregnant woman, but sometimes it would cost two lives.

Mrs. Jia Zhang looked miserable, and was about to ask what the disadvantages of a cesarean section were, when her son Jia Dongxu said, "Do it, we are willing to give my wife a cesarean section!"

Jia Zhang glared at her son.

She knew it very well.

The third aunt asked Li Ping'an to have a cesarean section and also removed the uterus. As a result, the third aunt could not continue giving birth.