Rebirth 1975: Tore up the call-back order at the beginning
Chapter 902: How effective is the medicine?
Saibei Pharmaceutical Research and Development Center. Director's Office!
Looking at the half bottle of small blue pills that Li Linzhang handed over, a trace of excitement flashed across Zhou Yang's face.
Dude, finally figured it out!
At that moment, he took the glass bottle containing the medicine, unscrewed the cap and poured out one, carefully looked at it again and again.
Whether judging from the color or the smell, it was indeed the sildenafil he knew.
But Zhou Yang didn't know the effect, after all, he had never taken this medicine before.
After a while, Zhou Yang came back to his senses, and then asked Li Linzhang, "Professor Li, how much medicine is in it?"
"There are 376 pills in total, and it took me a lot of effort to get them out!"
"How effective is this medicine?" Zhou Yang asked again.
Li Linzhang glared at him and said, "I haven't tried it, why don't you take it back and try it?"
To be honest, Li Linzhang was very dissatisfied with this research project.
Originally, he was conducting clinical trials on the lipid-lowering drug atorvastatin in Yangcheng, and the results were about to come out, but he received an order from here to come back quickly.
As soon as he returned to the laboratory, Zhou Yang called him over and gave him a plan to study this little blue pill.
When Li Linzhang learned that Zhou Yang asked him to study the medicine, his heart was broken, angry and firmly disagreed.
As a serious pharmaceutical research scientist, how could he waste his time on researching this "unscrupulous" medicine.
But couldn't stand Zhou Yang's soft-heartedness, and in the end Li Linzhang had no choice but to accept this task.
Zhou Yang heard the "resentment" in Li Linzhang's heart, and immediately smiled and said: "Look at you with a gun and a stick, isn't it just for you to study this medicine, as for it?"
"As for, if people know that I worked with you to create this drug, it may be the biggest stain on my career!" Li Linzhang said depressedly.
"Professor Li, you think too much. This is the gospel for men. I don't know how many men will thank you in the future..."
"Hurry up and let them thank you, Director Zhou. Don't forget our agreement!" Li Linzhang reminded.
In order not to let this research become a stain on his career, Li Linzhang put forward two requirements at the beginning of the research on the little blue pill.
The first requirement is that he does not need any assistants when researching this medicine, and if there is any problem, Zhou Yang needs to personally help him.
The second requirement is that after the successful research of this drug, it cannot be said that he made it.
"Professor Li, don't think about it anymore, this is a good opportunity to make your name in history!" Zhou Yang said with a smile.
"Don't think about it... don't think about it, this medicine has nothing to do with me!" Li Linzhang said firmly.
"Okay... just do as you say, I won't tell anyone that you developed this medicine!" Zhou Yang said.
"That's good, I have something to do over there, so I won't tell you!"
After speaking, Li Linzhang turned and left Zhou Yang's office.
After watching Li Linzhang leave, Zhou Yang looked at the small pills on the table and felt worried.
Once any drug is developed, it must be verified for its effectiveness, that is, clinical trials.
Even if Zhou Yang is actually making generic drugs right now, this step is still inseparable, it's just a matter of time.
For example, when he imitated fluoxetine, Lin Wanwan was used as a subject for symptomatic observation.
Another example is atorvastatin, which is prepared for Guo Yamin. With him, the effect is clear at a glance.
But this little blue pill is different. It does not treat common diseases. This kind of disease cannot be described in words, and the effect of the medicine cannot be displayed on the spot.
More importantly, although he and Li Linzhang made the small blue pills in front of him according to the recipe in memory, it was the first time Zhou Yang made this kind of medicine, no matter in his previous life or in this life.
So how effective it is remains to be verified.
You must know that the little blue pill in history originated from an "accident". The original research on this drug was not to make men stronger, but to find new ways to treat cardiovascular diseases including angina.
At that time, nitrates were effective drugs for the short-term treatment of angina attacks, but their long-term clinical value was limited by drug resistance.
Through the pharmacological mechanism of nitroglycerin to relieve angina pectoris, medical scientists have discovered that type five phosphodiesterase (can play a role in relaxing blood vessels, and vasodilation can increase blood flow, thereby relieving angina pectoris.
Subsequently, Pfizer began to explore based on this.
Through a series of chemical synthesis and improvement, Pfizer chose the drug uk-82480 among many compounds after comprehensive evaluation of various activities, which was later named sildenafil.
But unfortunately, as a drug for treating cardiovascular diseases, sildenafil failed in clinical research.
But the story didn't end there. During the clinical research, a side effect of sildenafil attracted the attention of researchers.
They found that male patients who took sildenafil had a "reaction" when they saw a beautiful nurse.
Some male volunteers with a relatively high oral dose found that after taking sildenafil, Xiao Ding Ding had more frequent erections and longer duration of erections, which means that this drug can make him more brave in bed.
So much so that after the trial ended, many volunteers were reluctant to hand over the drug.
In this way, a drug that can treat male erectile dysfunction was born by chance.
Pfizer, but countless volunteers came to test the drug, and finally discovered the magical properties of this drug, and the effect has been verified countless times
But what he wants now is nothing, how to test this?
If you don't want to try it, that's okay, after all, this medicine will eventually be put on the market and used by countless people.
If it doesn't work, isn't that smashing the signboard?
And although Zhou Yang wanted to harvest the world with this medicine, he didn't want to harm people.
After thinking about it again and again, he decided to take the medicine back first, and then think of a solution later.
But no matter what, the little blue pill was finally produced, which was extremely important to Zhou Yang himself, the entire Sickle Project, and even men all over the world.
Once the efficacy of this medicine is verified, Zhou Yang can hand it over to Yan Gengdong, and let them operate and promote this killer weapon with Hong Kong Island as the center.
Zhou Yang is very looking forward to the market performance of the little blue pill. You must know that although this medicine is the result of accidental insertion, its performance in the market is not bad at all.
Historically, the little blue pill dramatically became the world's first oral drug for the treatment of male erectile dysfunction, just as the invention of penicillin brought a breakthrough in conquering infectious diseases.
This little blue pill is not only known as the miracle medicine that "men have been waiting for 4000 years", but also has become the "money printing machine" of the pharmaceutical giant Pfizer.
In the year when the drug came out, doctors wrote more than 300 million prescriptions for 700 million patients, involving as many as 5000 million Viagra products, with sales reaching 7.7 million US dollars.
By the end of 1998, Viagra had landed in 40 countries, and Pfizer, where it was located, had a revenue of 232 billion US dollars that year.
In the following 20 years, the cumulative sales of the little blue pill reached 340 billion US dollars, making it a myth in the history of world medicine.
Although the time is now 20 years earlier, Zhou Yang believes that the market value of this drug will not change because of the advance or retreat of time.
After all, as long as a man's sense of powerlessness is difficult for ordinary people to understand, in order to be a "real man", most people are still willing to empty their wallets.
It can be said that in the next 20 years, this little blue pill will surely become the money printing machine of Weiyuan Company.
At the same time, the best boosters and whetstones of the Sickle Project...
........
ps: Deletion, deletion and modification, this chapter has been written for more than three hours, I feel a little helpless!
Looking at the half bottle of small blue pills that Li Linzhang handed over, a trace of excitement flashed across Zhou Yang's face.
Dude, finally figured it out!
At that moment, he took the glass bottle containing the medicine, unscrewed the cap and poured out one, carefully looked at it again and again.
Whether judging from the color or the smell, it was indeed the sildenafil he knew.
But Zhou Yang didn't know the effect, after all, he had never taken this medicine before.
After a while, Zhou Yang came back to his senses, and then asked Li Linzhang, "Professor Li, how much medicine is in it?"
"There are 376 pills in total, and it took me a lot of effort to get them out!"
"How effective is this medicine?" Zhou Yang asked again.
Li Linzhang glared at him and said, "I haven't tried it, why don't you take it back and try it?"
To be honest, Li Linzhang was very dissatisfied with this research project.
Originally, he was conducting clinical trials on the lipid-lowering drug atorvastatin in Yangcheng, and the results were about to come out, but he received an order from here to come back quickly.
As soon as he returned to the laboratory, Zhou Yang called him over and gave him a plan to study this little blue pill.
When Li Linzhang learned that Zhou Yang asked him to study the medicine, his heart was broken, angry and firmly disagreed.
As a serious pharmaceutical research scientist, how could he waste his time on researching this "unscrupulous" medicine.
But couldn't stand Zhou Yang's soft-heartedness, and in the end Li Linzhang had no choice but to accept this task.
Zhou Yang heard the "resentment" in Li Linzhang's heart, and immediately smiled and said: "Look at you with a gun and a stick, isn't it just for you to study this medicine, as for it?"
"As for, if people know that I worked with you to create this drug, it may be the biggest stain on my career!" Li Linzhang said depressedly.
"Professor Li, you think too much. This is the gospel for men. I don't know how many men will thank you in the future..."
"Hurry up and let them thank you, Director Zhou. Don't forget our agreement!" Li Linzhang reminded.
In order not to let this research become a stain on his career, Li Linzhang put forward two requirements at the beginning of the research on the little blue pill.
The first requirement is that he does not need any assistants when researching this medicine, and if there is any problem, Zhou Yang needs to personally help him.
The second requirement is that after the successful research of this drug, it cannot be said that he made it.
"Professor Li, don't think about it anymore, this is a good opportunity to make your name in history!" Zhou Yang said with a smile.
"Don't think about it... don't think about it, this medicine has nothing to do with me!" Li Linzhang said firmly.
"Okay... just do as you say, I won't tell anyone that you developed this medicine!" Zhou Yang said.
"That's good, I have something to do over there, so I won't tell you!"
After speaking, Li Linzhang turned and left Zhou Yang's office.
After watching Li Linzhang leave, Zhou Yang looked at the small pills on the table and felt worried.
Once any drug is developed, it must be verified for its effectiveness, that is, clinical trials.
Even if Zhou Yang is actually making generic drugs right now, this step is still inseparable, it's just a matter of time.
For example, when he imitated fluoxetine, Lin Wanwan was used as a subject for symptomatic observation.
Another example is atorvastatin, which is prepared for Guo Yamin. With him, the effect is clear at a glance.
But this little blue pill is different. It does not treat common diseases. This kind of disease cannot be described in words, and the effect of the medicine cannot be displayed on the spot.
More importantly, although he and Li Linzhang made the small blue pills in front of him according to the recipe in memory, it was the first time Zhou Yang made this kind of medicine, no matter in his previous life or in this life.
So how effective it is remains to be verified.
You must know that the little blue pill in history originated from an "accident". The original research on this drug was not to make men stronger, but to find new ways to treat cardiovascular diseases including angina.
At that time, nitrates were effective drugs for the short-term treatment of angina attacks, but their long-term clinical value was limited by drug resistance.
Through the pharmacological mechanism of nitroglycerin to relieve angina pectoris, medical scientists have discovered that type five phosphodiesterase (can play a role in relaxing blood vessels, and vasodilation can increase blood flow, thereby relieving angina pectoris.
Subsequently, Pfizer began to explore based on this.
Through a series of chemical synthesis and improvement, Pfizer chose the drug uk-82480 among many compounds after comprehensive evaluation of various activities, which was later named sildenafil.
But unfortunately, as a drug for treating cardiovascular diseases, sildenafil failed in clinical research.
But the story didn't end there. During the clinical research, a side effect of sildenafil attracted the attention of researchers.
They found that male patients who took sildenafil had a "reaction" when they saw a beautiful nurse.
Some male volunteers with a relatively high oral dose found that after taking sildenafil, Xiao Ding Ding had more frequent erections and longer duration of erections, which means that this drug can make him more brave in bed.
So much so that after the trial ended, many volunteers were reluctant to hand over the drug.
In this way, a drug that can treat male erectile dysfunction was born by chance.
Pfizer, but countless volunteers came to test the drug, and finally discovered the magical properties of this drug, and the effect has been verified countless times
But what he wants now is nothing, how to test this?
If you don't want to try it, that's okay, after all, this medicine will eventually be put on the market and used by countless people.
If it doesn't work, isn't that smashing the signboard?
And although Zhou Yang wanted to harvest the world with this medicine, he didn't want to harm people.
After thinking about it again and again, he decided to take the medicine back first, and then think of a solution later.
But no matter what, the little blue pill was finally produced, which was extremely important to Zhou Yang himself, the entire Sickle Project, and even men all over the world.
Once the efficacy of this medicine is verified, Zhou Yang can hand it over to Yan Gengdong, and let them operate and promote this killer weapon with Hong Kong Island as the center.
Zhou Yang is very looking forward to the market performance of the little blue pill. You must know that although this medicine is the result of accidental insertion, its performance in the market is not bad at all.
Historically, the little blue pill dramatically became the world's first oral drug for the treatment of male erectile dysfunction, just as the invention of penicillin brought a breakthrough in conquering infectious diseases.
This little blue pill is not only known as the miracle medicine that "men have been waiting for 4000 years", but also has become the "money printing machine" of the pharmaceutical giant Pfizer.
In the year when the drug came out, doctors wrote more than 300 million prescriptions for 700 million patients, involving as many as 5000 million Viagra products, with sales reaching 7.7 million US dollars.
By the end of 1998, Viagra had landed in 40 countries, and Pfizer, where it was located, had a revenue of 232 billion US dollars that year.
In the following 20 years, the cumulative sales of the little blue pill reached 340 billion US dollars, making it a myth in the history of world medicine.
Although the time is now 20 years earlier, Zhou Yang believes that the market value of this drug will not change because of the advance or retreat of time.
After all, as long as a man's sense of powerlessness is difficult for ordinary people to understand, in order to be a "real man", most people are still willing to empty their wallets.
It can be said that in the next 20 years, this little blue pill will surely become the money printing machine of Weiyuan Company.
At the same time, the best boosters and whetstones of the Sickle Project...
........
ps: Deletion, deletion and modification, this chapter has been written for more than three hours, I feel a little helpless!
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