Rebirth 1975: Tore up the call-back order at the beginning

Zhou Yang stood there for more than ten minutes, and then he came back to his senses under Liu Yunlong's reminder.

After that, he didn't stay in the first district, but took the special products from his hometown brought to him by Lu Zhengjun and walked towards the village.

Lu Zhengjun also said just now that the food in it is for food, so it's better to take it home for his wife and daughter to taste.

It's just that on the way, he kept thinking about the scythe project in his mind.

It's not that Zhou Yang doesn't have the explosive drugs that Yan Gengdong needs, but he doesn't know which one to choose.

In fact, as a medicinal chemist, Zhou Yang participated in the development of more than ten kinds of drugs in his previous life.

And there are no less than a hundred kinds of imitated drugs, many of which are blockbuster drugs from large foreign companies.

After thinking about it carefully, he felt that there were three kinds of drugs that met Yan Gengdong's needs, namely Lipitor, Humira and Xiaolan Tablets!

Lipitor, that is, atorvastatin drugs, common on the market such as atorvastatin, pitavastatin, etc., are all this type of drugs.

This drug was obtained by Japanese scholars in the 70s by cultivating Monascus to obtain lovastatin, which opened the chapter on hmg-coa reductase inhibitors. Because of its superior lipid-lowering effect and small adverse reactions, statins quickly became a hot research topic.

Since fda approved lovastatin in 1987, it has successively approved simvastatin, pitavastatin and fluvastatin, and atorvastatin is already the fifth hmg-coa reductase inhibitor approved by fda.

Lipitor was approved in December 1996, went public in early 12, and reached a sales peak of US$1997 billion in 2006. Lipitor has accumulated a revenue of US$138.3 billion for Pfizer behind it.

The second drug that Zhou Yang is optimistic about is Humira, namely adalimumab.

This is a TNF inhibitor, mainly applicable to rheumatoid arthritis, ankylosing spondylitis, Crohn's disease, psoriasis and other immune diseases.

Because of its good curative effect and small adverse reactions, adalimumab quickly detonated the demand for the treatment of immune diseases and became the gold standard in many therapeutic fields.

Adalimumab is a wonderful product, an all-around player, and a king of drugs that can be met but not sought after.

Since Humira was launched in 2003, its cumulative sales have reached 20 billion US dollars in less than 1159 years, and the sales of this drug have not yet reached its peak, and will further increase in the later period.

It is conservatively estimated that the cumulative sales of Humira may approach or reach 2000 billion US dollars.

The third is the well-known Viagra, which is also a blockbuster drug from Pfizer, which was launched in 1998.

The birth of Viagra was also an accident—its active ingredient, sildenafil, was originally designed for cardiovascular diseases, relieving high blood pressure and angina.

However, due to the less obvious effect of sildenafil on cardiovascular expansion, Pfizer has already planned to give up this drug.But during clinical trials in the 1990s, interesting side effects were accidentally discovered in male testers.

The researchers found that clinical trial participants were unwilling to hand over the rest of the drug after receiving the test drug.

The nurses further observed that many of the male test subjects were lying on their stomachs when they were examined by the nurses, and an attentive nurse reported this, saying that the men were embarrassed by the erections.

It turns out that the effect of sildenafil on releasing nitric oxide and dilating blood vessels is more effective on another part.

On March 1998, 3, FDA approved the listing of Viagra, and the first oral impotence drug became famous.

After the launch of Xiaolan Tablets, it quickly became the fastest growing prescription drug in sales.In April 1998 alone, more than 4 doctors wrote more than 20 million prescriptions for 300 million patients, involving as many as 700 million Viagra products.

By the end of 1998, Viagra had landed in 40 countries, and Pfizer's revenue reached 232 billion US dollars that year.

For more than 20 years, Viagra has been a steady source of income for Pfizer.

To be honest, these three drugs all meet the needs of Yan Gengdong and the Sickle Project, but it is worth carefully weighing which one to choose.

After all, each of these drugs is worth tens of billions of dollars, and only one of them can instantly turn a company into a unicorn.

If all of them were brought out at once, not only would it not be a good thing for the small company controlled by Yan Gengdong, but it would also be a certain risk for Zhou Yang himself.

Therefore, although the things will be taken out one by one in the end, it is not a one-off stud, and it will flow slowly.

Just thinking about it, the two of them had arrived at the gate of the Zhou family!

As soon as he entered the door, Zhou Yang saw Li Youwei standing on the kang and walking up and down, the little boy in his arms was moaning.

On the ground, the same is true for the mother-in-law.

Apparently, the two brats were having a row again.

Seeing Zhou Yang walking in with a big bag, Li Youwei immediately asked, "Why did you come back at noon, have you eaten yet?"

"Have eaten, have you and your mother eaten?"

"Not yet, these two little guys are too noisy, they cry as soon as they put them down, they won't let my mother and I cook at all!" Li Youwei said helplessly.

"Then I'll cook for you now!" Zhou Yang said.

At this time, the mother-in-law immediately said: "Xiao Yang, you can't cook a woman's confinement meal. If you hold the baby, I will do it!"

"Row!"

At that moment, Zhou Yang took over the child from his mother-in-law.

The little guy was half asleep and half awake, maybe his father's embrace was not as comfortable as his grandma's. After Zhou Yang hugged him, the corner of the little guy's mouth twitched, and he quickly moaned.

Zhou Yang immediately patted her on the back lightly, and the little guy finally calmed down.

I haven't seen it for a few days, the little guy has become heavier and looks better.

After a while, Zhou Yang finally coaxed the little guy to sleep, and then carefully took out an envelope from his pocket, and put it on the edge of the Kang.

"Money again?" Li Youwei asked in surprise.

A few days ago Zhou Yang quietly gave her an envelope, which contained 1000 yuan, which really shocked her.

Unexpectedly, only a few days later, I saw the same style of envelope again.

"Well, it contains my salary, and the other part belongs to Wen Hui!" Zhou Yang said.

"Wen Hui?"

"Well, Old Yan sent all his salary to me!"

"Yeah, send it all to us, what did Brother Yan spend?"

Although Li Youwei knew that Yan Gengdong had gone back, she didn't know exactly what to do when she went back, let alone that Yan Gengdong had gone to Hong Kong Island now.

"Don't worry about him, his daily expenses are managed by the state, and his salary is not needed!" Zhou Yang said.

"Oh, then let's save his salary for Wen Hui!"

"I think so too, our family can't use it!" Zhou Yang said.

"Okay! Then when you have time, let's take Wen Hui to the credit union!" Li Youwei said.

"Row!"

"By the way, what's in that bag? Why does it smell good to me?" Li Youwei sniffled and asked.

It was only then that Zhou Yang remembered the things he had brought back, and immediately said: "Lao Lu just came, and he brought some specialties from the capital!"

As he spoke, Zhou Yang gently put his son on the kang, then brought the cloth bag over, and took out the contents one by one.

Beijing roast duck, Dongzhimen dim sum, marijuana, bean stuffed pancakes... Good guy, there are more than a dozen kinds!

Although each one is only a small bag, but the value is not cheap.

Seeing these delicious foods, Li Youwei's eyes narrowed.

She is greedy for everything when she is in confinement, but the old lady is more strict. She is not allowed to eat this, and she is not allowed to eat that. Every day is basically brown sugar porridge and boiled eggs. After half a month, she feels that she is tired of eating .

Seeing that there was meat, it was still the delicious roast duck that he had eaten before, so he immediately made a gesture of silence to Zhou Yang, then freed his hand and directly tore off a duck leg and started to eat it.

Zhou Yang didn't expect that his always prudent wife would do the same, so he couldn't help laughing.

Just laughing, the mother-in-law suddenly came in from the main room, saw the big duck leg in her daughter's hand, and immediately said: "How big is it, stealing it again!"

Zhou Yang immediately smiled and said, "Mom, don't talk about her, it's not that you can't eat meat during confinement, just don't eat too much!"

"You, just get used to her..."

Just as he was talking, there was a sudden roar of cars outside the door, and then he saw a jeep parked outside the door.

Then, the car door opened, and Fan Debiao got out of the car in a hurry!

And kicked open the wooden fence door of Zhou Yang's house, and ran in with a solemn expression.

ps: Everyone thinks that medicine is suitable, and those who like Xiaolan tablets raise their hands!