People are in Konoha, scientific achievements are followed by blood
Chapter 25 Developing therapeutic agents
Among these four questions, the first three are technical issues, while the last one is outside the technical scope.
In order to solve the fourth problem, he needed an experimental site located in the village so that he could rationalize his research.
This step is to take the initiative to put your experiment under the eyes of the village and provide the village with an explanation, so as to reduce the resistance that may be encountered in subsequent launches.
So, Yayoi returned to the village, spent a lot of energy, and even sold out her beauty (showing off her cuteness) to borrow an open space from the group of female veterinarians in the animal training class.
Although their muscles are a little exaggerated, these veterinary ladies are quite easy to talk to.
Since following Tsunade back to Konoha, Yayoi has been among the various classes in the medical department for a long time.
With his harmless appearance, he had already become familiar with the young brothers and sisters in the medical department.
The veterinary ladies all know that he is Tsunade's disciple, and have seen his superb palm senjutsu skills many times, and speak highly of him.
Therefore, when he learned that Yayoi wanted to develop a therapeutic potion, the monitor of the animal training class not only did not underestimate him, but happily lent him a large open space.
Not only that, after learning about his need for experimental rabbits, he also kindly sponsored some excellent experimental rabbit breeds for him.
She also enthusiastically said: If you don't have time to cultivate it, you can come back to her and ask for it at a discounted price.
After accepting these rabbits, the more Yayoi looked at them, the more familiar they became.
He carefully identified them, but was surprised to find that the appearance of these rabbits was very similar to the "Japanese big-eared white rabbit", a common experimental rabbit species in the laboratory in his previous life.
This kind of rabbit is a medium-sized fine-bred rabbit that is selected and bred based on the Chinese white rabbit.
It has fast growth, strong fecundity, good mothering ability, large lactation capacity, good adaptability, cold resistance, tolerance to rough feeding, excellent cortex and good meat quality.
Due to the large ears and clear blood vessels, it is easy to collect blood and inject, and the experimental operation effect is ideal, so it is mostly used for experimental rabbits.
After long-term training by ninjas in the animal training and recuperation class, and no one knows what ninjutsu was used, this rabbit's reproductive capacity is nearly twice as fast as that of its kind on earth.
These cute little rabbits can be regarded as solving part of Yayoi’s urgent needs.
Now that the experimental site and experimental animals are available, the development of a healing agent can be officially put on the agenda.
Generally speaking, after a scientific research project is established and the research direction is determined, the first thing to do is to read the literature in the relevant direction.
The first purpose of doing this is to find out if there are any ready-made scientific research results in the academic world that can be used directly to reduce duplication of work. This is also the reason why the more powerful academic papers are cited more times. .
Another purpose is to prevent collisions with fellow drivers.
What Yayoi is doing now is to check a lot of information from the Medical Department and Orochimaru, which is similar to reading literature.
He is in the ninja world, so he naturally doesn't worry about colliding with others. The ninja world doesn't pay attention to intellectual property rights and piracy of genuine products.
At the same time, he was also certain that Konoha did not have such powerful healing medicine at this time.
His purpose in reading these materials was mainly to find ideas for solving three technical problems.
After half a month of crazy reading, Yayoi finally found the solution to the first two problems from some unpopular information.
The first question is about how to actively refine the specialized Yang Escape Chakra.
The information to solve this problem comes from the Konoha Medical Department. It is the conjecture of the medical ninjas on the mechanism of refining and using Yang escape chakra and promoting the self-healing of the injured cells after long-term use of medical ninjutsu.
If my guess is correct, the source of this information can be traced back to the Second Hokage period, and it can be regarded as one of the by-products of studying Hashirama cells.
At the same time, it is also closely related to a large-scale medical ninjutsu in Konoha, "The Jutsu of Healing and Regeneration," and is the basis for the forbidden jutsu "Creative Regeneration" that Tsunade later developed.
The second question is how to solve the source of tissue fluid or blood.
The key to solving this problem is to promote the body's metabolism and strengthen hematopoietic function.
In previous scientific theories, there were two types of hematopoietic growth factors: "colony stimulating factors" and "interleukins", which can act on hematopoietic precursor cells and lymphocytes to promote their differentiation and maturation.
Orochimaru also has similar records in his research, and even directly developed related ninjutsu to achieve his purpose of taking excessive amounts of blood.
This ninjutsu does not take into account the body of the subject and is very harmful to the human body. It is in line with Orochimaru's consistent practice of treating experimental subjects as consumables.
But Yayoi wanted to use this technique on herself, so naturally it couldn't be so simple and crude.
This needs to be improved to weaken the side effects of ninjutsu.
The idea of improvement is quite simple: weakening the effect of the technique itself will naturally reduce the damage it causes to the body.
It took another week for Yayoi to weaken the technique to a point where her body could bear it.
After the two key issues are resolved, you can directly configure the treatment potion.
The first batch of potions prepared were quite effective.
In the experimental group, several experimental rabbits were subjected to different forms of injuries: ruptured internal organs, severe concussion, electric shock, burns, and knife wounds.
After taking the medicine, except for a few individuals with extremely weak vital signs, most of the experimental rabbits recovered and seemed to have no obvious side effects.
The only drawback of this batch of potions is that the storage time is too short.
With the addition of anticoagulants, it can only be stored for one to two days at most.
Even if stored in a low temperature environment, the validity period can only be extended to two weeks.
However, even though the treatment potion is not perfect yet, it has already met Yayoi's expectations.
His main goals in developing therapeutic agents were threefold:
One is to highlight one's talents, to show one's own value, to transform oneself from a disciple of Tsunade into the second one in Tsunade (in medical aspects), to seize a certain status in Konoha's medical system, and to gain some connections with senior officials. (Official) Qualifications for dialogue.
The second is to build a network of relationships, using his identity as a medical ninja to make friends with the injured and patients, manage certain interpersonal relationships, and gain enough voice in the village (civilian).
The third is to obtain a large amount of financial income to fund one's own research.
There is another reason why we do not continue to improve the medicine, and that is:
During this month of drug development, Yayoi had already spent the little money she had saved, and even owed foreign debts to several veterinarian ladies.
Even the materials used to prepare anticoagulants were misappropriated from the inventory of Orochimaru's laboratory.
If I continue this experiment, I'm afraid I won't have to pay the debt with my body.
In order to solve the fourth problem, he needed an experimental site located in the village so that he could rationalize his research.
This step is to take the initiative to put your experiment under the eyes of the village and provide the village with an explanation, so as to reduce the resistance that may be encountered in subsequent launches.
So, Yayoi returned to the village, spent a lot of energy, and even sold out her beauty (showing off her cuteness) to borrow an open space from the group of female veterinarians in the animal training class.
Although their muscles are a little exaggerated, these veterinary ladies are quite easy to talk to.
Since following Tsunade back to Konoha, Yayoi has been among the various classes in the medical department for a long time.
With his harmless appearance, he had already become familiar with the young brothers and sisters in the medical department.
The veterinary ladies all know that he is Tsunade's disciple, and have seen his superb palm senjutsu skills many times, and speak highly of him.
Therefore, when he learned that Yayoi wanted to develop a therapeutic potion, the monitor of the animal training class not only did not underestimate him, but happily lent him a large open space.
Not only that, after learning about his need for experimental rabbits, he also kindly sponsored some excellent experimental rabbit breeds for him.
She also enthusiastically said: If you don't have time to cultivate it, you can come back to her and ask for it at a discounted price.
After accepting these rabbits, the more Yayoi looked at them, the more familiar they became.
He carefully identified them, but was surprised to find that the appearance of these rabbits was very similar to the "Japanese big-eared white rabbit", a common experimental rabbit species in the laboratory in his previous life.
This kind of rabbit is a medium-sized fine-bred rabbit that is selected and bred based on the Chinese white rabbit.
It has fast growth, strong fecundity, good mothering ability, large lactation capacity, good adaptability, cold resistance, tolerance to rough feeding, excellent cortex and good meat quality.
Due to the large ears and clear blood vessels, it is easy to collect blood and inject, and the experimental operation effect is ideal, so it is mostly used for experimental rabbits.
After long-term training by ninjas in the animal training and recuperation class, and no one knows what ninjutsu was used, this rabbit's reproductive capacity is nearly twice as fast as that of its kind on earth.
These cute little rabbits can be regarded as solving part of Yayoi’s urgent needs.
Now that the experimental site and experimental animals are available, the development of a healing agent can be officially put on the agenda.
Generally speaking, after a scientific research project is established and the research direction is determined, the first thing to do is to read the literature in the relevant direction.
The first purpose of doing this is to find out if there are any ready-made scientific research results in the academic world that can be used directly to reduce duplication of work. This is also the reason why the more powerful academic papers are cited more times. .
Another purpose is to prevent collisions with fellow drivers.
What Yayoi is doing now is to check a lot of information from the Medical Department and Orochimaru, which is similar to reading literature.
He is in the ninja world, so he naturally doesn't worry about colliding with others. The ninja world doesn't pay attention to intellectual property rights and piracy of genuine products.
At the same time, he was also certain that Konoha did not have such powerful healing medicine at this time.
His purpose in reading these materials was mainly to find ideas for solving three technical problems.
After half a month of crazy reading, Yayoi finally found the solution to the first two problems from some unpopular information.
The first question is about how to actively refine the specialized Yang Escape Chakra.
The information to solve this problem comes from the Konoha Medical Department. It is the conjecture of the medical ninjas on the mechanism of refining and using Yang escape chakra and promoting the self-healing of the injured cells after long-term use of medical ninjutsu.
If my guess is correct, the source of this information can be traced back to the Second Hokage period, and it can be regarded as one of the by-products of studying Hashirama cells.
At the same time, it is also closely related to a large-scale medical ninjutsu in Konoha, "The Jutsu of Healing and Regeneration," and is the basis for the forbidden jutsu "Creative Regeneration" that Tsunade later developed.
The second question is how to solve the source of tissue fluid or blood.
The key to solving this problem is to promote the body's metabolism and strengthen hematopoietic function.
In previous scientific theories, there were two types of hematopoietic growth factors: "colony stimulating factors" and "interleukins", which can act on hematopoietic precursor cells and lymphocytes to promote their differentiation and maturation.
Orochimaru also has similar records in his research, and even directly developed related ninjutsu to achieve his purpose of taking excessive amounts of blood.
This ninjutsu does not take into account the body of the subject and is very harmful to the human body. It is in line with Orochimaru's consistent practice of treating experimental subjects as consumables.
But Yayoi wanted to use this technique on herself, so naturally it couldn't be so simple and crude.
This needs to be improved to weaken the side effects of ninjutsu.
The idea of improvement is quite simple: weakening the effect of the technique itself will naturally reduce the damage it causes to the body.
It took another week for Yayoi to weaken the technique to a point where her body could bear it.
After the two key issues are resolved, you can directly configure the treatment potion.
The first batch of potions prepared were quite effective.
In the experimental group, several experimental rabbits were subjected to different forms of injuries: ruptured internal organs, severe concussion, electric shock, burns, and knife wounds.
After taking the medicine, except for a few individuals with extremely weak vital signs, most of the experimental rabbits recovered and seemed to have no obvious side effects.
The only drawback of this batch of potions is that the storage time is too short.
With the addition of anticoagulants, it can only be stored for one to two days at most.
Even if stored in a low temperature environment, the validity period can only be extended to two weeks.
However, even though the treatment potion is not perfect yet, it has already met Yayoi's expectations.
His main goals in developing therapeutic agents were threefold:
One is to highlight one's talents, to show one's own value, to transform oneself from a disciple of Tsunade into the second one in Tsunade (in medical aspects), to seize a certain status in Konoha's medical system, and to gain some connections with senior officials. (Official) Qualifications for dialogue.
The second is to build a network of relationships, using his identity as a medical ninja to make friends with the injured and patients, manage certain interpersonal relationships, and gain enough voice in the village (civilian).
The third is to obtain a large amount of financial income to fund one's own research.
There is another reason why we do not continue to improve the medicine, and that is:
During this month of drug development, Yayoi had already spent the little money she had saved, and even owed foreign debts to several veterinarian ladies.
Even the materials used to prepare anticoagulants were misappropriated from the inventory of Orochimaru's laboratory.
If I continue this experiment, I'm afraid I won't have to pay the debt with my body.
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