Homo sapiens.

At the same time, this is also to prevent European and American pharmaceutical companies from jumping over the wall. After all, their reliever drugs can continue to be sold.

The only places where Ai Qingling is approved for sale are Hongsawady, Siam, and Luzon. It is estimated that other places will have to wait for a while.

Especially in Europe and the United States, in fact, big pharmaceutical companies such as Pfizer and Johnson & Johnson are very grateful for Hongshawadi's gold dollar trade policy, which has prevented Aoba Group's drugs from entering the European and American markets in a short period of time.

After Xie Bin and Tian Hemeng signed the contract, they were not in a hurry to return to Siam, but continued to negotiate other business.

For example, Aoba Medical intends to purchase a batch of drugs and production lines produced by Chia Tai Company.

After all, in this new contract, CP Company needs to pay Aoba Medical 5.025 million gold dollars. With such a large amount of money, CP Company cannot use gold, so it can only use products to replace products.

This time, Qingye Medical has taken a fancy to Chia Tai's general medicines and production lines.

Even a second-hand production line is fine. The relationship between Qingye Medical and European and American pharmaceutical companies and equipment manufacturing areas is not very good, so we can only pick up second-hand production lines from Zhengda.

Anyway, there are some drugs that can satisfy common diseases, and it takes a waste of time and money to develop them by ourselves, so we simply buy ready-made production lines.

Chapter 123 Imitation

According to the requirements of the headquarters, Tian Hemeng proposed a 10 billion procurement plan.

Among them, the quota for imported drugs is 5 million yuan, and the quota for production line purchases is 5 million yuan, and it is promised that when it is necessary to purchase drugs from outside in the future, it will give priority to purchasing from Chia Tai Company.

Xie Bin looked at the list of imported drugs in his hand, and his eyes were about to burst out.

Listed above are [Entecavir Dispersible Tablets], [Magnesium Isoglycyrrhizinate Injection], [Diammonium Glycyrrhizinate Enteric-Coated Capsules], [Entecavir Maleate Tablets], [Irbesartan Hydrochlorothiazide Tablets], [Suvastatin Calcium Tablets], [Alprostadil Injection]......A total of 44 kinds of drug import demand.

Some of these medicines are needed by Qingye Pharmacy, and some are needed by Qingye Hospital.

However, Xie Bin did not have the authority to decide on the introduction of production lines, but he estimated that the headquarters would not refuse. After all, Chia Tai Company does not sell, and other companies will.

Aoba Medical requires many production lines, mainly focusing on cardiovascular and cerebrovascular, anti-tumor, orthopedics, pain relief, and supplementation.

As for the drugs for liver disease, respiratory system, and digestive system, they are not on the list, mainly these drugs will be developed by Aoba Medical in the future, and there is no need for Zhengda’s production line.

A total of 13 drug production lines were selected.

After communication between Xie Bin and the headquarters, the two sides quickly reached an agreement that Chia Tai Pharmaceutical will package and sell a batch of drug production lines that are ready to be phased out or that have already been phased out to Qingye Medical.

After signing the contract, CP Company's reserves in Qingye Bank rose to more than 5 million.

However, Zhengda Company has no idea of ​​withdrawing money. After all, the money must be spent. With the spread of Ai Qingling's effect, and the fact that Ai Qingling has not been approved for sale in many regions, this means that within a period of time , Hongsawadi, Siam, and Luzon will become the main channels for global AIDS patients to obtain medicines.

……

If we talk about Ai Qingling, the special drug for AIDS, it just makes people around the world feel a little bit interested.

Then the rabies buster has become a necessity in many underdeveloped areas.

After all, these underdeveloped areas do not have the conditions to popularize rabies vaccine, whether it is given to humans or pets, there is not enough penetration rate.

For example, in Siam, there was a large-scale rabies outbreak in Siam in 18 years.

Many people who have been bitten by cats and dogs generally do not have enough awareness of prevention, or think that the price of rabies vaccine is too high, and they did not get rabies vaccine in time, and when they get sick, there is basically no cure.

Although the price of rabies buster is very high, it is still effective during the onset period, which makes its importance soar.

Of course, Tian Hemeng knows that at the current price, there are only a few who are willing to buy Rabid Busters.

Therefore, the production capacity of Rabid Buster's production line is very low. Even if the production line is fully open, it can only produce 2 boxes a month. What's more, it only works for 3 hours a day on average, and the monthly production capacity is only 2000 boxes.

The production volume is low, and the demand is not high, so the sales price is naturally high.

For this niche drug, Aoba Medical is concentrated in a small town near Taunggyi for joint production.

Usually, one drug is normally produced for a week, and then the employees are transferred to the next production workshop to produce another drug, and the cycle is repeated in turn.

Using this production plan is also a last resort.

After all, this is the fate of niche drugs. The market is so big, and it is too difficult to maintain a production line at full capacity.

Otherwise, Aoba Medical would not sell Ai Qingling in limited quantities, just worried that the market would be saturated and the production line would be scrapped.

This is why many big pharmaceutical companies do not like to develop radical drugs.

Everything is for profit.

……

Also for profit.

Hundreds of generic drug companies in Tianzhu have also recently heard the news.

A large generic drug company in Mumbai has purchased some Ai Qingling through the Tianzhu people in Yangon.

In the laboratory, the boss Ali asked eagerly, "Dr. Kaisha, how is the research going?"

Dr. Kaisha, who was wearing a white coat, shook his head: "Mr. Chairman, I'm very sorry, I'm afraid we can't imitate this medicine."

"Why?" Ali asked unwillingly: "Could it be that our equipment is not working?"

"Mr. Chairman, this is not a problem with equipment, but that we don't have raw materials." Dr. Kaisha spread his hands.

Ali frowned: "Raw materials?"

"Yes, it is the raw material. This new drug requires the use of specialized bacteria, similar to bacterial strains such as penicillin and streptomycin."

"Then let's go buy the strains!"

The corner of Dr. Kaisha's mouth twitched slightly: "Hehe, the key is that Aoba Medical did not announce that it uses that kind of bacteria as raw materials. According to my experience, it is definitely not a common medicinal bacteria."

"Damn it! These greedy vampires are hiding such crucial information."

Hehe, Dr. Kaisha complained secretly, you want to imitate other people's new drugs, and you blame others for not publishing the technical details, please don't be so shameless.

Ali suddenly had a whimsical idea: "I heard that antibiotics can be artificially synthesized now, can we experiment with this method of production?"

"Uh...Mr. Chairman, the active ingredients of the other party's new drug are macromolecular organic substances. To synthesize them artificially, it is necessary to figure out which part of the structure of this macromolecule is working, and this kind of research requires a lot of funds. The research time will also take a long time..." Dr. Kaisha explained helplessly.

When he heard that it would take a lot of money and a long time, Ali immediately showed a disappointed expression.

Generic drug companies like him rely on imitating new drugs developed by others, and it is basically impossible to expect them to invest a lot of money to develop a drug with an uncertain future.

In fact, not only Tianzhu generic pharmaceutical companies are secretly researching imitation.

Even major pharmaceutical companies in Europe and the United States are secretly studying how to imitate them.

It's just that they all encountered the same problem.

That is what kind of bacteria Aoba Medical used to isolate these three new types of antibiotics. Now European and American pharmaceutical companies have not found similar macromolecules, so they can only study the structures of these macromolecules, hoping to find some effective antibiotics. The anti-virus structure, and then for reference and improvement.

What kind of bacteria did Aoba Medical use?

The answer is genetically recombined phages, these phages have been modified beyond recognition by Li Qingye, and then use these phages to continuously fight against HIV, and select the phages that can resist and kill HIV.

That is to say, the strains that produce new antibiotics are not naturally occurring bacteria. Other laboratories have no way to obtain such gene-recombined bacteria, and they have no way to imitate them in a short time.

This is like when penicillin first came out, those high-yield strains were the core secrets of various pharmaceutical companies and even countries.

Without high-yielding strains, the production cost of ordinary penicillin is comparable to gold.

The strains currently used in Aoba Medical do not even exist in nature, and other laboratories cannot even extract a small amount. Faced with this situation, how to imitate them?

You must know that this is not an ordinary inorganic chemical drug, but an organic macromolecule, and it is very difficult to synthesize it artificially.

This is also one of the advantages of targeted antibiotics. Without strong enough genetic technology, it is impossible to imitate targeted antibiotics in a short period of time.

Chapter 124 New Industry ([-])

20, April 3.

The world is still in a strangely peaceful state.

And in some corners of the world, life is still the same as before, like a pool of stagnant water.

But there are also some places where completely new mutations have occurred.

For example, the old street area in Hongshawadi.

As the area at the junction of Hongshawadi and Huaguo, this place used to be synonymous with chaos, gambling, kidnapping, flour and kidneys, and demons danced here.

But since the end of last year, the Laojie area has officially entered a new page.

After more than three months of integration, the current Laojie area has been renamed the Shanbei Region, which occupies the northern part of the Shan Plateau and is at the same level as the province and state of Hongshawadi.

Fang Xinwu and his two younger brothers drove an off-road vehicle all the way north to Nankan Town. The north of Nankan Town is the national border and the opposite is Ruili.

He came here this time because he was entrusted by others.

When he came to the entry point of the port, Fang Xinwu saw a lot of well-wrapped Chinese, and Xiang Ruili entered Nankan Town. Among them, there were many people who looked nervous and looked around worriedly.

Fang Xinwu's younger brother, Maung Heshui, picked up a wooden sign with Fang Xinxin written on it.

After waiting for about half an hour, a girl pulling a suitcase appeared in front of Fang Xinwu.

"Brother Xinwu, I'm Xinxin." The girl is Fang Xinxin. Although she wears a mask, her frail and thin body is hard to hide.

Fang Xinwu nodded: "Get in the car!"

Maung Heshui quickly took the other party's suitcase.

A group of people got on the off-road vehicle, and Xinxin was very silent along the way, just silently looking at the dense jungle outside the car window.

Vehicles headed south along the highway.

Two hours later, we arrived at Xingwei Town, 80 kilometers away.

After this period of expansion and transformation, this small town has become a small city with a large scale.

However, Fang Xinwu's car did not stop, but drove towards a nearby mountain, which is close to the west of Xingwei Town, and the altitude is relatively high.

After a short section of winding mountain road, we arrived at our destination.

This is a small village built on a high mountain platform. The whole village has been renovated and a lot of infrastructure has been added.

Using concrete pillars, steel structures and iron bamboo materials, Aoba Construction Company built a large five-story building here in just 46 days.

When I came out of the parking lot, there was a sign at the door in Burmese and Chinese: Xingwei Town Yunding Nursing Home.

"How many?" The front desk at the gate asked with a smile.

Before Fang Xinwu came, he had already learned about the situation of Yunding Sanatorium through the official website of Qingye Medical: "Four of them, one of them needs medical services."

"ID card."

Fang Xinwu and others handed over their ID cards or passports.

The waiter quickly registered the basic information, and then she asked with a smile, "Which one needs medical services?"

"This lady, she needs a package A medical service."

The so-called A package is the medical package for the treatment of AIDS. If it is for the treatment of rabies, it is the K package. The waiter nodded and then entered the information:

"Package A for one person, here is the list of charges, please confirm your signature, and then pay the fee."

Fang Xinwu took the bill of charges.

[Package A (AIDS treatment), 50000 yuan for drugs, 1400 yuan for basic nursing care (seven days), 1400 yuan for housing (seven days), 700 yuan for customized meals (seven days)]

[Three ordinary guest rooms, stay for 7 days, the room fee is 2100 yuan, the meal fee is 1050 yuan...]

[A total of 56650 yuan, the company does not accept any foreign currency payment, only accepts gold dollars or gold. ]

Fang Xinwu directly took out his bank card at Qingye Bank: "Swipe the card!"

The waiter inserts the bank card into the device: "Please enter the password."

Fang Xinwu entered the password, and the machine spit out the bill.

"Thank you for your patronage, welcome to come next time." The waiter smiled and nodded.

Another waiter immediately led a group of people to the guest room area of ​​the nursing home. After passing through the small park transformed with fruit trees, many people can be seen walking here.

Fang Xinwu heard that many of them spoke Mandarin, obviously many of them were Chinese.

Before planning to launch new drugs, the executives of Qingye Group discussed some things, such as it is difficult for new drugs to enter China in a short period of time.

But there are not a few AIDS patients in Huaguo, and these people definitely need drugs.

Therefore, there are only two channels for these patients to obtain drugs, one is through smuggling, and the other is going abroad.

Considering that the price of medicines in Siam and Luzon is very high, the retail price of the medicines in Hongshawady, as the origin of the medicines, is only 5 gold dollars, which is naturally very cost-effective.

The only trouble is that the local social environment in Hongshawadi is not pleasant.