Li Qingye thought for a while, then nodded and said: "Alright, let's use this opportunity to let Luzon and Hongshawadi close the country for a while."

"I understand." Chen Jianxiong also knew that this was one of the few things they could do now.

As for other things, even the Homo sapiens company, which has greatly increased its power, has no ability to intervene in the family affairs of the five hooligans.

Suddenly Li Qingye ordered again: "During the investigation, you should send some of the target's blood samples as soon as possible. I need to study it and make preparations just in case."

"Yes, I'll arrange it right away." Chen Jianxiong has no doubts about Li Qingye's scientific research ability in the biological field. As long as Li Qingye is willing to make a move, Homo sapiens company will at least not be helpless.

Seeing Chen Jianxiong who left in a hurry, Li Qingye sat on the sofa, lost in thought.

This sudden situation affected many of his plans.

Originally, he wanted to take action against Du Jianxin's family in the near future, but now that the planes are grounded and the immigration inspection has been strengthened, the soldiers who are about to perform the mission will have no way to go there for a while.

Li Qingye was not upset about this either, after all it is impossible for everything to go smoothly.

And it's not that he doesn't have a backup plan, it just takes a few months to adjust.

Pulling his thoughts back to reality, Li Qingye washed his face in the bathroom, then passed through the disinfection area, and then passed through layers of tight gates, and came to his exclusive laboratory.

The AIDS target drug he developed for Domino and others has entered the final stage of testing.

More than a dozen AIDS-infected scumbags were being held in a special ward by the military assistants, and they were constantly monitoring the conditions of these experimental subjects.

"How's it going?"

The assistant reported to him on the 15th: "There is no abnormality in the body of the experimental subject, and the HIV in the body is basically undetectable, but it cannot be ruled out as a falsehood."

HIV is very cunning. It often evades the killing of drugs, and then hides until the effect of drugs has passed, and then continues to make waves.

The target drug developed by Li Qingye is different from traditional AIDS treatment drugs, and it is not the RNA technology that has just emerged in recent years.

This is a customized drug that targets a specific gene target, somewhat similar to an advanced version of an RNA vaccine.

The core of its technology is to quickly determine the gene sequence of the virus, and then use genetic recombination technology to create a suicide virus specifically targeting the virus, and then inject the suicide virus into the patient's body, so that the suicide virus and the virus in the patient's body will die together.

In fact, this thing is one of the derivative technologies of the gene bomb.

Therefore, this targeted drug will not cause the patient to produce antibodies, but it can kill the virus and is a special drug.

Since it is an exclusive drug for a specific virus, it is necessary to carry out careful genetic testing of the virus in the patient's body before this exclusive drug can be manufactured.

In other words, there is no way for targeted drugs to work on all AIDS, it can only kill specific HIV.

For example, in the 15 experimental subjects in front of us, the HIV in their bodies is called AIDS, but the genes of these AIDS are different, and an exclusive target drug must be customized for each individual.

According to the traditional technology, the production cost of this exclusive target drug is absolutely sky-high.

Fortunately, Homo sapiens' technology is different from traditional genetic technology.

The technical points of manufacturing exclusive target drugs have the following two aspects:

First, the genetic detection technology. In this regard, Homo Sapiens currently owns biochips and DNA storage devices, in which the genetic point detection technology that can be quickly detected is applied, and the results can be obtained almost instantly.

Second, genetic recombination technology, Li Qingye designed a universal virus bomb framework - [TYBD-(X)-JYZD].

This framework is very simple, and the general framework consists of six parts: immune deception gene sequence, structural stability gene sequence, target chimeric gene sequence, blasting gene sequence, self-replication restriction gene sequence, and timed disintegration gene sequence.

Among them, the target chimeric gene sequence is the position for quickly inserting the virus target gene.

Although in the link of target gene insertion, only a small part of the target gene will be successfully and completely inserted into the frame each time.

But as long as one of them is successful, rapid genetic testing can be used to extract the successful part, and then use hormone and virus culture medium to start self-replication until enough target drugs are obtained.

This link usually only takes about 5 to 12 hours.

In fact, the simplified version of this technology is the current RNA vaccine technology.

The advantage of the target drug is that it kills the virus very quickly, almost 100%, and does not give the virus time to mutate. It also does not make the virus resistant to drugs, and has almost no side effects on the patient's body.

The disadvantages are also very obvious. The patient's body cannot produce antibodies, and there is a risk of secondary infection, so it cannot be used in areas without relevant supporting facilities.

This target drug is more suitable for viruses such as AIDS, Ebola, and rabies, but not for viruses such as smallpox and influenza.

The reason why it is not suitable for smallpox and influenza is not that it cannot be used, but that these viruses have the characteristics of aerosol transmission. The virus is killed in the patient's body, but there may be other sources of infection in the surrounding environment, which can easily cause repeated infections.

Once the infection is repeated, the previous target drug cannot be used for treatment, but the virus gene must be re-detected, and the target drug will be manufactured according to the virus gene sequence.

Although Homo sapiens' genetic testing technology is very fast and very cheap, it only costs a few cents a time; the raw materials for cultivating target drugs also cost only a dozen yuan.

The problem is that this repeated tossing can easily lead to leaks, and it also requires a lot of manpower, especially valuable professional medical manpower.

Therefore, Li Qingye will adopt two other solutions for aerosol-transmitted viruses such as smallpox.

One is a simplified version of targeted drug technology-RNA vaccine.

The other is a bacteriocin (ie, an antibiotic) that targets a general target.

In fact, these two technologies are not bad, at least the technology in Li Qingye's hands is more perfect than the current RNA vaccine technology and antibiotic technology of the same type for humans.

The general principle of the two is the same, but Li Qingye has made an upgrade and improvement.

For example, RNA vaccine technology, Li Qingye's full name of the technology is: composite - multi-target combined RNA vaccine technology.

Specifically, for popular virus strains, more than 10 gene targets are determined, and then several 10-target RNA vaccines are developed, and then these vaccines are combined and used together.

Faced with this kind of vaccine, even an RNA virus with a very fast mutation rate is hard to beat with two fists.

The same is true for targeted antibiotics.

This is also the drug that Li Qingye intends to market separately through Aoba Group and Homo Sapiens.

As for the exclusive target drug, this technology can only be used in a small range internally, after all, it involves gene bomb technology.

Chapter 1 The Guest ([-])

Manila.

Austin Hotel, two tourists, a man and a woman, stayed here.

The man is a black-haired white man in his 20s, wearing one earring, sitting on the sofa, looking helplessly at the phone screen:

"From tomorrow, Luzon intends to initiate a restriction order for a period of three months."

After taking a shower, the blond woman who was drying her hair with a hair dryer looked indifferent: "Then consider it as a tourist here."

"Christine, the tourist attractions may be temporarily closed, so we can't stay in the hotel all the time, right?"

Christine turned off the hair dryer, and asked winkingly: "Are you not satisfied with me in the hotel all the time? Dear Anthony."

"No, I've been in the hotel all the time. I feel like I'm in jail." Anthony seemed to recall some bad memories.

Christine took out a lady's cigarette, lit it, and lay on the sofa, flipping through the Luzon travel guide on YouTube.

Anthony twitched his ears slightly, closed his eyes and sat on the sofa, as if he was listening to something. After ten minutes, he opened his eyes:

"There are so many cockroaches here."

Christine was very calm about this: "Huh... Where are there no cockroaches? Unless it is the Antarctic and the North Pole."

"Is there anywhere you want to go?" Anthony changed the subject.

"Let's go to Bonifacio Avenue first! I heard that there are many Spanish colonial buildings there, and it is also a famous commercial street."

"OK!"

In the afternoon, after three o'clock.

Wearing shorts and short sleeves, the two appeared shoulder to shoulder on Bonifacio Avenue.

Anthony, holding a camera, took pictures around until the two came to the door of San Agustin Church, a church built during the Spanish colonial period.

The two went directly into the church.

On the rows of benches inside, many locals were praying.

Anthony and Christine sat on the bench in the back, quietly listening to the hymns played by the tape recorder, and several priests were baptizing a newborn child.

The two of them did not make any other moves. After half an hour, they quietly left the church and continued to visit various attractions in Manila.

In a shop selling small toys.

Like a little girl, Christine held a bamboo kitten and asked with a smile, "Anthony, this kitten is so cute!"

Anthony, with a helpless face, leaned against the checkout counter: "I can barely lift it."

As for Anthony's complaints, Christine seemed not to have heard it, and continued to hold various small toys and play with them in her hands.

The owner of the toy store is a middle-aged man with a smile on his face all the time. There are two employees in the store, a man and a woman.

Anthony smiled and asked: "These toys are very good, but unfortunately there are no such toys in California."

The boss replied with a smile: "These toys are all hand-woven or carved in our local area, but they are very rare."

"Oh Maikar, are these handmade works of art?" Anthony asked in surprise.

"Haha, not exactly. Many of those bamboo and wood products are handmade, while plastic and resin products are produced in factories." The boss explained.

Anthony picked up a bamboo cat litter: "It's such a pity, this cat litter is sold in California, and it is estimated to sell for $100."

"Really? That's a pity." The boss's expression didn't change much.

Anthony didn't go on, but looked at his watch and called out, "Dinner time is almost here, honey."

Hearing that it was time for dinner, Christine could only hold on to her three favorite bamboo toys and come to the counter to pay.

After the two left, the boss was still busy with his head down.

Inside the Austin hotel room.

The two who had dinner were lying on the sofa again.

Through the floor-to-ceiling windows, you can see the night view of Manila Harbor.

"Any gains?"

Christine shook her head: "The church is very clean, the jewelry store doesn't have any styles I like, and the toy store is just so-so!"

"Then how about going to Limanan tomorrow? I heard that there are a lot of beach projects there." Anthony suggested.

"airplane?"

Anthony shook his head and pointed to the tourist map: "Take the train and just take a tour of the scenery along the way."

"OK, you arrange it!"

The next day, the two bought train tickets to the southern city of Lima.

The slow train is not much different from that of America. The whole journey is about 300 kilometers and takes about four or five hours.

Sitting by the car window, Christine observed the scenery and the city along the way.

As the train passed through the city of San Pablo, the scenery on both sides began to change significantly, because they began to enter the territory of the Fernando family.

Around Manila, whether urban or rural, are densely populated areas.

After passing San Pablo City, there was a sense of separation.

The rural population here is not large, but the urban population is denser than Manila.

The two temporarily canceled their trip to the southern city of Lima and planned to stay in the upcoming port of Lucena for a day.

After leaving the train station, Christine stretched herself, while Anthony looked for a taxi, but the situation here was different from what they encountered at the Manila airport, and there were no taxi drivers swarming up.

It wasn't until they walked out of the train station to the service street that they saw green taxis lined up on the side of the road, and the drivers were all in their own cars.

Many customers just opened the door and got on the seat, and then the taxi started.

Anthony pulled the suitcase, walked to a taxi, and knocked on the window glass: "Hello, driver, how much is it to go to a better hotel nearby?"

The driver with the green dragon on the left and the white tiger on the right showed his big yellow teeth: "A better hotel nearby? Then Feng Rao Hotel, 86 pesos."

Anthony looked at the other taxis again, and found that the other drivers did not intend to come over to snatch passengers, so he nodded: "OK."

The two got into a taxi.

Da Huangya stepped on the accelerator and quickly drove towards the Fengrao Hotel.

Anthony asked curiously: "Are the taxis here different from those in Manila?"

"Almost!" Dahuangya replied perfunctorily.

Anthony did not continue to ask about this, after all, sometimes asking too much would easily arouse the other party's suspicion.

And 86 pesos is really not high, but the two were charged 500 pesos at the Manila airport.

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