Rule department scholar
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Ai Lixin also nodded, "It's right to believe in Zhao Yi, this is our experience, and based on our understanding of him...this time, it's amazing!"
"Why……"
Shen Qian's mind was full of question marks, she didn't guide the meaning of the work that Zhao Yi explained at all, why did she say that when she got here, she was about to produce big results?And it was Ai Lixin and Li Ming who spoke together.
Obviously.
She doesn't know Zhao Yi yet.
When Zhang Wei and Zhu Qi entered the main laboratory and heard about this incident, they had the same reaction as Ai Lixin and Li Ming.
"It's amazing this time!"
"Cancer research, a result is world-class!"
"Doctor Shen, congratulations in advance!"
"It's right to believe in Zhao Yi, you will soon have world-class medical research results."
"Do not worry!"
"It's true what Zhao Yi said, I really envy you..."
Chapter 542 Brand new discovery!
main laboratory.
The words of Ai Lixin, Li Ming and others made Shen Qian feel very confused. She didn't understand why. Several researchers said this, and it seemed that there was a kind of enthusiasm for Zhao Yi.
Even though Zhao Yi's personal achievements are very high, and the research and development achievements in the medical field are very breakthrough, but...
"Perhaps what they say is true?"
"Academician Zhao can have such a high achievement, there must be a reason. Academician Zhao is optimistic about it, and it is certain that he has discovered..."
"It must have been discovered?"
"So it's just because my level is not enough?" Shen Qian thought carefully, and suddenly had a little expectation.
Probably the main reason is that her level is really not enough. She is a cancer expert in a tertiary hospital, but there are too many similar experts.
She is a front-line doctor, not a purely medical scientific researcher. In the field of medical theory research, she has not had any achievements worth mentioning.
Shen Qian had some expectations, and she also hoped that she could produce results. After returning to the laboratory, she opened the notebook and carefully looked at the recorded work content.
"Under the microscope, take a clear image of the sample at the highest magnification!"
This is easy.
After a busy afternoon, Shen Qian finished the shooting and uploaded the photos to the computer.
Follow-up work started the next day.
Zhao Yi asked her to compare the detection proteins in the cells to see the differences between cancer cells and normal cells.
This work is very professional and meticulous, the most important thing is to separate the detection protein.
Shen Qian designed three methods to separate proteins, and compared them, calculated data and recorded them respectively.
She has been busy for three days in a row.
On the last day, the comparison was almost done, and Zhao Yi also came over as a routine to take a look, and worked with Shen Qian to do the final comparison.
The comparison result is printed out.
The comparison results contained a series of data. Shen Qian looked at each result carefully for more than ten minutes, and finally shook her head with a wry smile, "Academician Zhao, everything is normal."
"There is basically no difference in the data of the two detected proteins separated by the three methods."
"Let me see!"
Zhao Yi was very calm. He took a leisurely sip of coffee before taking the report. After reading it for about a minute, his eyes suddenly lit up and he said, "Doctor Shen, you are wrong."
"what?"
Shen Qian was stunned again.
Zhao Yi pointed to a place and said earnestly, "Look here, there are differences in the comparison of the three data." After he finished speaking, he pointed to the other two places. be taller."
"Also, in the item of abnormal detection, here and here, the detection protein value of cancer cells is a little higher."
Zhao Yi continued to speak seriously.
Shen Qian took a pen to draw a few positions, then read it again seriously, and said in confusion, "But, Academician Zhao, the difference values are all within the range of deviation fluctuations. No matter what kind of test is done, as long as there are two samples, The results won't be exactly the same."
"I don't believe in 'range', 'range' is not definite." Zhao Yidao, "We do scientific research, not according to the content in the book, and the normal range and deviation range stipulated in the book are not necessarily all normal. .”
"But……"
Shen Qian asked a little confused, "If you don't look at the normal range, how can you look at it?"
"Feel!"
Zhao Yi said affirmatively, "Scientific research feels very important. Of course, the feeling is illusory, and it can also be analyzed by data. You see, the comparison results of the few places I pointed out are regular."
"The first few places are high in normal cells, and the latter are high in cancer cells."
"These data, if I remember correctly, all represent the RD interval of the detected cells, that is, corresponding to DNA and RNA gene detection, right?"
Shen Qian immediately looked back and found that everything was just like what Zhao Yi said, and several data indeed corresponded to the RD interval of the detected cells.
In fact, she didn't find it normal.
The compared data contains more than 300 items, and there is no direct division of intervals. Most of the comparison items are just code names, while the range of RD intervals is very large, including more than [-] data, and the distribution is jumpy.
No matter how good a researcher is, it is impossible to tell at a glance that several data are in the RD interval because they do not compare the detected cells for a long time.
In addition, there are more than 50 data in the RD interval, and only five data show a certain pattern, which does not seem to explain anything.
Of course.
It may also be a discovery.
"Maybe it's because I don't know much about data analysis?" Shen Qian thought with some doubts, "And Academician Zhao, a top mathematician and computer expert, must be very sensitive to numbers."
She still has doubts in her heart, because it is difficult to really explain the regular "small anomalies" in several data.
Zhao Yi said, "As long as you find something, you can try it." He directly explained the work, "Next, we will design experiments around these points, try to amplify the signal, and then look at the final result."
"Okay~~"
Shen Qian nodded hesitantly. One reason for her hesitation was that she didn't quite understand it, and the other was that it was very difficult to amplify the signal. It was not just separating the detection protein from the cells, but separating the detection protein. She was not sure she could do it.
Zhao Yi also knew that the difficulty was high, so he continued, "In this way, you may not be enough alone, and it will take too long. We need to get the results as soon as possible. I will find a few more people."
After he finished speaking, he went to the main laboratory and yelled at the door, "Who is free at work to help with the separation of the detected protein? It will take a few days."
There are quite a few people in the main laboratory, including Zhang Wei, Ai Lixin, and Li Ming, as well as several associate researchers and assistant researchers.
After Zhao Yi yelled, the associate researcher and assistant researcher were embarrassed to speak, but Ai Lixin and Li Ming shouted directly, "I'll go!"
"I go!"
The two spoke in unison.
Zhao Yi shook his head and said, "This is not too complicated a job, one is enough." He was referring to the researcher, several researchers doing protein separation together, it is really a waste of talent.
"I go!"
Ai Lixin immediately said, "For my current experiment, Lao Zhu can just come, and I'm not needed at all. Don't you see that I'm idle here?"
"You don't have time for me!" Li Ming said, "For my group of research, Zhang Wei alone is enough!" After he finished speaking, he continued, "Zhao Yi, this is my strong point. And last time And last time, I was doing cell research and protein separation, so I should come!"
"What is my strength? I'm not my strength? I happen to have nothing to do to help. When Dr. Shen said to help last time, I was the one to go!"
"That's what you rushed to, and you don't know what kind of ghosts you have in mind."
"What are you talking about! Who cares, how can you just throw dirty water! I don't know who it is, so that the lesbians in the institute are scared. I guess they did something bad behind the scenes..."
Ai Lixin and Li Ming confronted each other and almost got into a fight.
Zhao Yi rubbed his forehead vigorously, glanced at Zhang Wei and still shook his head, fine protein separation work requires an experienced old researcher, Zhang Wei's level must be a bit poor.
"Forget it, stop arguing!"
"Come on!"
Zhao Yi simply asked the two to come together. Anyway, they seemed to be very free, and they were still in the mood to argue a few words, and they seemed to be in good spirits.
Ai Lixin and Li Ming nodded together, looked at each other and turned their heads and snorted coldly.
The other people in the main laboratory were just watching the excitement, but to their surprise, Zhao Yi didn't ask any questions at all, and ordered a few people directly.
Including Yan Yi, there are a total of five associate researchers, and an intern led by Zhu Qi, so let them come with them.
Zhao Yi, two researchers, and other people, nine of them went to the laboratory where Shen Qian was, and couldn't stand after entering.
"This is Dr. Shen."
"These two, Lao Ai and Li Ming, do you know each other? Yan Yi and Zhou Lijun..."
Zhao Yi helped to make introductions one by one, and then said, "What we are going to do is to detect the proteins of the cells, separate the proteins in the RD region, separate cancer cells from normal cells, and perform several types of comparisons."
He assigned work, "Lao Ai's group, Li Ming's group, and Dr. Shen's group, each of you draw up a separation method, discuss it together, and strive to get the result as soon as possible."
"it is good!"
"no problem!"
"that's it!"
Several associate researchers were familiar with Li Ming and Ai Lixin, so they were grouped with them respectively. Zhao Yi asked Yan Yi, another female researcher, and Shen Qian to do the separation and comparison experiment.
The separation of proteins in the RD region is not easy, but it also depends on the level of the researchers. Two top cell experts and a few associate researchers made the work much easier. It took less than half an hour for them to finalize the process. There are two separation methods.
The finalized separation method was proposed by Ai Lixin and Li Ming, and their level is indeed very high. Shen Qian also proposed a method, but it was rejected as soon as he said it.
The evaluation given by Li Ming is, "The operation requirements are too delicate, and the operation process has a great impact on the results!"
In fact, his private comment was, "A method only used by rookies."
The method proposed by Shen Qian is very standard, and it is no problem to put it in a book, but it is not enough in the eyes of Li Ming and Ai Lixin. Operational impact.
If the experimental operation requirements are too high, a small mistake in the middle may have a major impact on the results.
In formal research, it is necessary to avoid similar designs in order to obtain more accurate results.
This is the level gap.
Shen Qian was also very depressed when her proposal was rejected, but she accepted it calmly. She had been working on the project for a few weeks, and she was familiar with Li Ming and Ai Lixin, and she also understood their ability level, which was indeed better than hers. a notch.
If she were placed in the Biomedical Research Institute, she would probably be at the level of an ordinary associate researcher, but she would not be as good as an associate researcher when it comes to professional fields such as protein isolation and cell research.
At the same time, Shen Qian also felt very stressed. She looked at the group of people in the laboratory with a wry smile, and felt that doing research together was a waste.
This is just a small project of 30!
Similar projects are taken over by individual research associates, and the researchers will definitely not devote their energy to such small projects. As a result, two researchers help with the project together, and they bring several research associates with them.
This lineup is too huge!
Even if it is a research project of several hundred or tens of millions, two top researchers lead the team, almost completely enough.
What Shen Qian didn't know was that everyone in the lab wanted to join in, because it was a project that Zhao Yi participated in, and Zhao Yi was very optimistic about it.
Zhao Yi is optimistic, can there be any small results?When writing a report, it's okay to put a name on it!
This kind of big achievement has a side-by-side discovery, even if there is no research contribution, it is enough to make up a good paper.
Who wouldn't want to join in?
With the participation of a group of researchers and associate researchers, the protein isolation work in the RD area progressed very quickly. In less than three days, more than a dozen sets of comparison experiments were completed, and a lot of comparison results were produced.
While a group of people were still doing experiments, Zhao Yi, Ai Lixin, Li Ming, and Shen Qian looked at the results of the experiments and compared them together.
There was no objection this time.
Ai Lixin pointed to a few places and said directly, "The abnormal signal is very clear. A certain detection protein in the RD region has an alienation reaction against the genetic variation of the cell."
"The signal is already obvious!" Li Ming also nodded.
Shen Qian was a little excited, "This should be a new discovery!"
"of course."
"If it's not a new discovery, wouldn't our work be in vain?" Li Ming followed up with a slightly excited tone.
All I can say is, a little bit.
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