Rule department scholar
Page 399
Then it's testing, testing, testing.
Finally, a very complex method is used to study the molecular mechanism of the 2CV-bing hydrogen molecule.
The task will be sent out soon.
The first step was done together by both parties. At present, it is only for the extraction of 2CV-Bing hydrogen molecules. There is no technical content, but the laboratory has used some, and mice that have been injected with Proteus and E. coli can extract some The blood was simply distributed to the 'Researcher Team'.
So you can start the second step.
After the assignment of research tasks was over, several people in Zhao Yi's laboratory left. Yan Xuelin asked Dai Tianqing, Han Hui and others to stay, and said seriously, "This time, we are under a lot of pressure. You are all researchers. , with rich experience and many successes, there are fewer people than him, but none of them have much experience, like the one named Fan Lei..."
He shook his head as he spoke, obviously meaning, 'Fan Lei is completely useless'.
Of course.
"If, that's what I mean, the research made them ahead, really, think about it, I feel very..." Yan Xuelin laughed as he said.
"No, boss, don't worry!" Dai Tianqing said confidently, "Lao Ai worked with me for ten years, and Zhang Wei was also brought out by me. I know them too well. Others, That Yan Yi has no experience, and Liu Chengjie is the same, they are all newcomers, if we lose to them, we really will be ashamed to come to the institute again."
"Yes, Lao Dai is right." Li Ming expressed his support.
Han Hui was a little worried, "You didn't consider Zhao Yi, did you?"
Dai Tianqing said, "Zhao Yi is very powerful and talented in scientific research, but no matter what, he can compare with how many of us? Three cobblers are better than Zhuge Liang. You won't lose, will you?"
"Right."
Han Hui nodded imaginatively.
Yan Xuelin also breathed a sigh of relief, "It's good that you have confidence. This research is also very important. We have competition, but the most important thing is cooperation."
"This is the discovery of Zhao Yi's laboratory. Whether it's you or them, half of the results are considered to be from Zhao Yi's laboratory. You can participate, including me, because of their credit. At most, you can add your name. , you don't mind this?"
"Of course, we know this. If Zhao Yi hadn't nodded, we wouldn't be able to participate." Dai Tianqing knew about this.
The others also nodded.
"Okay, that's it." Yan Xuelin stood up, "Come on, try to finish it as soon as possible. I'm really looking forward to it. Maybe this time it's not weaker than Vif's research."
"come on!"
"come on!"
Chapter 358 This gap is too big!
Research on the molecular mechanism of medical pathology is a specialty of the Institute of Biomedicine.
Most of the biomedical sciences have produced many achievements in the past few decades, and many achievements have been made in the past few decades. The most recent major achievement is the study of the molecular mechanism of the HIV force gene vif hijacking protein.
Therefore, everyone involved in the project of the Biomedical Research Institute, including people in Zhao Yi's laboratory, as well as researchers such as Dai Tianqing, Han Hui, Li Ming, etc., are very interested in the research project on the molecular mechanism of 2cv-Binghydrogen anti-HIV infection. They are confident and think that it is only a matter of time before they are completed. How to conduct research requires only a simple discussion. Each of them can independently design the general flow of the research process.
Of course.
It is still very difficult to study the molecular mechanism of medical pathology.
Research at the molecular level requires analysis of many problems, and many of the most high-end and professional equipment will be used. There are a lot of data to be measured and calculated in the process, and the experimental research process is still very complicated.
At the end of the small meeting to clarify the division of labor, the 'Dai Tianqing Research Group' and Zhao Yi's laboratory began to do research separately. Because there is a certain competition, and it is still a confidential scientific research, everyone hopes to produce results quickly.
The first step is to inject Escherichia coli and Proteus into the mice, and extract the blood after the immune reaction, so as to purify the solution substance containing 2cv-bing hydrogen molecules.
It only takes time for this step to complete.
Because Zhao Yi's laboratory already had the extracted solution, and there were more than a dozen mice that had been injected with bacteria for one week or two weeks, and some of them were also given to the 'Dai Tianqing Research Group', and the two sides entered the second one at the same time. stage.
The second stage is divided into two steps, one is to identify the anti-HIV infection effect of 2cv-Bing hydrogen molecule, and the other is to find methods and strategies to analyze at which level the anti-HIV infection effect occurs.
For example, the protein level.
For example, gene synthesis blocking level.
Another example is the process that occurs when genes play an effect.
and many more.
Zhao Yi's laboratory directly skipped the first step. Everyone is very confident in Zhao Yi's conclusion, and with the previous experimental data, there is no need to continue to verify the effect of 2cv-Binghydrogen molecule against AIDS infection.
The 'Dai Tianqing Research Group' still carried out the verification work, but it was carried out together with the research work, and the initial focus was still on the former.
Out of caution in treating research, they must first confirm that it is effective, otherwise the follow-up work will be useless.
Five days later.
The experiment designed by Ai Lixin and Liu Chengjie found that the sample injected with 2cv-Bing hydrogen molecule mixed solution has obvious anti-HIV infection effect, because the concentration of 2cv-Bing hydrogen molecule injected is high, and the anti-infection effect of HIV is very high. Well, the immune system of the mice did not decrease rapidly.
At the same time, the detection of the concentration of HIV also confirmed a problem.
The concentration of HIV has not decreased significantly, and even increased.
Ai Lixin said, "This shows that the 2cv-Bing hydrogen molecule can play an anti-infective role, but it does not directly kill HIV, or even directly block the synthesis of HIV, but plays a role at other levels."
"Probably at the level of infection..."
This conclusion is very important.
AIDS is worthy of being an experienced researcher. Zhao Yi used "The Law of Cause and Effect" to confirm his conclusion, and decided to say, "The next focus of our work is to study the 2cv-Bing hydrogen molecule, which one is in the process of virus infection?" The role of enlightenment at the level."
The research of Zhao Yi's laboratory is rapidly entering the third stage.
Yan Xuelin also occasionally came over to check on the progress and listened to their small internal meetings. He still had other thoughts.
In the competition between the two research groups, he must be on the side of the 'Dai Tianqing Research Group', mainly because each member of the 'Dai Tianqing Research Group' is a senior researcher. Not a newly established laboratory, especially in this laboratory there are not many people, most of them are new recruits, and the third place is only an associate researcher who has just been promoted for a few years, the 'researcher group' loses If so, he, as the director, feels that face has nothing to do with it.
After listening to the small meeting, Yan Xuelin asked about the details and hurried to the central laboratory.
That's where the 'Dai Tianqing Research Group' works.
"How is your research going?" Yan Xuelin asked directly, ignoring the small talk.
"It's going well!"
Dai Tianqing said excitedly, "We have confirmed that the 2cv-Bing hydrogen molecule does have a very high anti-AIDS infection effect, and the next focus is to study the 2cv-Bing hydrogen molecule, specifically at the level of virus suppression or infection. played a role."
Li Ming walked over cheerfully, and was also pleased with the progress of the research.
Yan Xuelin couldn't be happy at all.
If I remember correctly, during the meeting at Zhao Yi's laboratory, the first sentence jumped directly to 'confirm that the 2cv-Bing hydrogen molecule plays a role in the infection level', and then directly assigned the next stage of work.
Just did research here?
He took a deep breath, did not say it directly, but pointed in a direction, "I think it is the infection level, skip the rigorous research process, and directly verify."
"That's not good?"
"If the verification is wrong, it takes more time."
"correct."
Dai Tianqing, Li Ming, and Han Hui stood up at the same time to express their doubts.
Yan Xuelin's words made them all shut up, "I can tell you that the conclusion has been confirmed over there. You can decide for yourself whether you want to listen or not."
He left after saying that.
The three looked at each other in disbelief.
Why is it so fast on the other side?
They just started to prepare for the research, and the opposite side even came up with the conclusion?
"Is it because they have done a lot of research before and have an experimental basis?"
"probably."
"It can only be like this."
Dai Tianqing nodded and said, "Let's just listen to the director and conduct a direct experiment to verify it. The results will come out in two or three days. Let's move on to the next step quickly."
……
After the "Dai Tianqing Research Group" set the goal, they acted very quickly. They quickly designed the experiment, and through a series of tests, it was verified that the 2cv-Bing hydrogen molecule works at the infection level.
The researchers were much more relaxed, and hurriedly held a small meeting to formulate the next step of the experiment.
Simultaneously.
The new experiment designed by Zhao Yi's laboratory has made new discoveries.
That was Zhao Yi's discovery.
Through continuous observation of the experiment, coupled with a series of test data, he quickly discovered that HIV does not destroy cells or divide, but reacts with 2cv-Bing hydrogen molecules, resulting in 'silence', or The phenomenon of 'dormant', in short, is that the ability to infect is greatly reduced.
Zhao Yi expressed his "guess" and discussed with the people in the laboratory. They analyzed two possibilities, one is that the 2cv-Bing hydrogen molecule acts on the protein structure of the outer layer of HIV, and the other is that it acts on the protein structure of the outer layer of HIV. At the genetic level, it weakens the ability to divide and reproduce after the gene is injected into the cell.
Zhao Yi quickly determined that it was acting on the protein level. He checked all the test data and some data related to HIV infection, and reached a conclusion according to the conditions.
Then the laboratory is designed for verification.
It is not easy to analyze whether the 2cv-Bing hydrogen molecule acts on the protein level or on the gene level, but in the verification work, you only need to do a little--
To see if HIV can invade cells.
The protein in the outer layer of any virus has two functions. One is to protect the genes inside, and the second is to help the genes invade into the cells. After completing the second task, the protein structure of the outer layer is to function, and it will was directly abandoned.
If HIV does not invade cells, it must be acting on the protein structure. After completing the invasion of cells, it must be acting on the gene level.
The experimental determination in this aspect is also very difficult. It takes a long time to wait. It took almost a week and several designed experiments to get the definite conclusion that the 2cv-Bing hydrogen molecule is indeed effective on AIDS. The protein structure of the outer layer of the virus.
This day Yan Xuelin came again.
Yan Xuelin came here every day to take a look around and care about the progress of the research. He really cared very much, because the results also represent the honor of the institute.
At the same time, Yan Xuelin also compared the progress of the two research groups, and hoped that the speed of the 'Dai Tianqing Research Group' could be faster.
When hearing Ai Lixin's report, "We have confirmed that the infection-inhibiting effect occurs at the outer layer protein level", Yan Xuelin thought about the progress of the 'Dai Tianqing Research Group' and wanted to give up .
The difference is too big!
When I came to the central laboratory of the institute, I heard Dai Tianqing report, "The last verification greatly accelerated our progress, thank you, we have designed a new experiment to analyze whether the infection occurred in Which level of the virus, but our analysis suggests that both protein and gene levels are possible.”
"How about over there?" Dai Tianqing asked in a low voice, "It should be at this step, right?"
"Correct."
Yan Xuelin replied weakly, "Just finished."
"Just finished? What do you mean?" Dai Tianqing was a little dazed.
Yan Xuelin took a deep breath and said, "I mean, they have already determined that the infection occurs at the protein level."
He sighed, patted Dai Tianqing on the shoulder and said, "Old Dai, don't be offended if you say something bad. I think, after these days, it might be a mistake to do research in groups. You always chase after them." It’s not a problem to use their conclusions to verify the progress, right?”
"..."
"Why don't you think about it and go over there to do research? Is it faster together?"
"..."
"Let's not be divided into groups, and the data, experiments, and results are all shared."
Dai Tianqing still hesitated, "But..."
"But what? You two times in a row, just to catch up on the progress and use their conclusions to verify. I didn't say anything, and they didn't know."
Yan Xuelin said very seriously, "If this goes on like this, what is the difference from stealing the results? Let people know what it looks like, and let you do it yourself. Do you have the confidence to catch up and surpass it?"
"..."
"..."
Dai Tianqing and Li Ming who came over stopped talking.
Catch up?
Anyway, there is no hope for the time being.
They found that the opponent was always one step ahead of them, and they had just verified the conclusion of the opponent, and the opponent came to the next conclusion.
None of them could imagine how the other side did the research.
This is not normal!
But it is really embarrassing for them to say that they don't need to be grouped and experiment together. They are all leaders of the laboratory and experienced researchers.
What should we do now?
Dai Tianqing and Li Ming looked at each other, not knowing what to do for a while.
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