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Except for the improved HX3 medicament, no other method has been found for the time being.

They are also working on the direction of further in-depth research on the improved HX3 drug. After a month, they can no longer suppress the virus at all.

After seeing the doctors in the isolation room injecting new drugs into the patients, the hearts of all the researchers were raised. After 10 minutes passed, everyone showed disappointment when they saw the patient who was still struggling with fear and talking nonsense on the hospital bed in the isolation room.

"Failed again."

Another failure made all medical scientists feel sad.The eyes of several old medical scientists were already red. They felt powerless in the face of this kind of disaster.

"According to the incomplete statistics of the WHO, the number of direct and indirect deaths caused by the 'Reaper Virus' has exceeded 5, the number of infected and confirmed cases has exceeded 9, and the number of people quarantined globally is close to 250 million. In the next month, if There is no specific medicine, and the death toll is expected to exceed 10. This is the largest man-made biological disaster in human history."

"Los Angeles reports that yesterday, a medical worker in Los Angeles was accidentally infected with the 'Reaper Virus' while handling the corpse, and due to excessive pressure, committed suicide by jumping off the building in the quarantine area."

According to Reuters news, a patient broke free from a fixed rope in a concentrated isolation area in France, killed a medical staff member and escaped from the isolation room, and released 60 virus-infected patients, causing riots in the isolation area and attempting to escape from the isolation area.

The riot resulted in the death of 3 medical staff, 7 medical staff and 1 chemical defense soldier were infected with the Reaper virus, and 9 infected people died.The chemical defense force of the French military has captured all the patients, and no infected person has escaped from the quarantine area. "

For two months, the news from various hard-hit areas in the world has put a heavy weight on the hearts of the international community. When going out to do any activities, one must be careful, for fear of being infected with the "Reaper Virus", the global economic loss is even more immeasurable .

Capital Tangshan Hospital.

Chen Mo, Wu Bing, and a group of team members wearing protective clothing were walking quickly to the isolation room in the test area.

Everyone had different expressions, either anxious or expectant, only Chen Mo and Wu Bing had relatively calm expressions.They're doing research, and they've been notified that a patient they're vaccinated with the experimental vaccine had an unusual reaction today.

With the support of Chen Mo's complete technical information and the help of team members, the research and development of the vaccine is developing in the direction Chen Mo expected, and the accuracy is very fast.

Wu Bing's team successfully found the protective antigen gene of the virus, and Chen Mo led the team to find a suitable mRNA as a vaccine system platform.

The drug has been tested several times, all of which ended in failure. The vaccine system platform has been improved several times. This is the 8th trial of their customized vaccine.

It's good to have a reaction.

At this time, the most frightening thing is that the medicine does not respond.

So when they received the news, everyone gave up their research and rushed over to the test area.

"pain."

"it hurts."

"Doctor, I'm in pain and uncomfortable."

When Chen Mo and Wu Bing entered the isolation room, they heard the patient's voice mixed with pain.The sound was not loud, but to the two of them, it was like the sounds of nature.

When the Reedman virus attack occurs, the patient is like a lunatic, and there is no such clear voice at all.

This shows that their vaccine has begun to have a little effect.

"Sir, why are you uncomfortable?" Wu Bing bent down and asked.

"The body hurts, and the brain hurts too." The patient seemed to hear Wu Bing's question and began to answer, as if talking in sleep, but there was a crying tone in his voice, obviously suffering great pain.

This answer made all the team members ecstatic.

There is an answer, indicating that the patient's consciousness has become somewhat clear, and the injected vaccine may have played a role.

Wu Bing asked a few more questions, but apart from the pain, there were no accurate answers to other questions, like a drunk who was half asleep.

"Health examination, you give him a blood test."

Chen Mo signaled to the team members who came over, and began to draw blood from the patient on the fixed bed.The other two team members unbuttoned the patient's hospital gown, and the bruise on the skin immediately attracted everyone's attention.

This bruise spreads all over the skin of the body.

It's not a symptom of Reedman virus, they've been dealing with it for months, that's for sure.

"It's like an allergy, and it's like poisoning." Wu Bing said.

Chen Mo nodded, agreeing with Wu Bing's statement: "Apart from the injection tube vaccine, did the patient take other medicines?"

"No, I strictly check the glucose injected by the patient. No other medical staff has come into contact with the patient." The team member in charge definitely shook his head.

"It might be related to the vaccine. Let's test the patient's blood first," Wu Bing said.

Ten minutes later, Chen Mo and Wu Bing came out of the isolation room when no results were found.As soon as the two came out, Shi Hongtu and others outside the isolation room could not wait to surround them.

When they heard that the patients here at Chen Mo had abnormal reactions, they immediately put down their research and came over.It's just that Chen Mo and Wu Bing are in the isolation room, it's not easy for them to go in, they are all waiting outside.

"How is it? Your research has progressed?"

Shi Hongtu and other immunology experts looked expectantly under the protective glasses.

Chen Mo and Wu Bing's team, because of the research on customized vaccines, has little hope for him.But after a few times, the group progressed faster than he had imagined.

Now the patient has responded, while the other groups, after injecting the experimental new drug, either went nowhere, or the patient died directly, with little progress, so they also hope that Chen Mo can create a miracle.

"The vaccine was injected three days ago. Depending on the situation, it should have played a little role. The patient's speech is no longer as nonsense as before." Wu Bing said.

As soon as these words came out, Shi Hongtu and several immunology experts were ecstatic.

If the patient's mental state improves, it means that the research has progressed, and this is definitely the news they most want to hear now.

"However, the patient's body is abnormal, and it is not sure whether it is an allergy or poisoning. It needs to see the results of the blood test." Wu Bing added.

"Okay, okay, let's wait for the blood test results." Shi Hongtu said with some surprise.

Chen Mo and Wu Bing bid farewell to Shi Hongtu and the others, and also entered the laboratory.

The team leaders of several other groups learned that Chen Mo's group had made progress, and had no intention of researching, so they came to wait with them.The waiting time is always very long, more than two hours, which makes several people feel that several months have passed.

And when several people were about to be unable to sit still, Wu Bing and Chen Mo came out of the laboratory.

Shi Hongtu's three steps turned into two, and he immediately walked up.

"The result is out?"

"Let's talk about it." Wu Bing looked at Chen Mo, with no joy or sorrow in his voice.

"Virus antibodies were detected in the patient's blood, and these antibodies have an effect on the virus and can clear the virus."

Chen Mo's words were like a fairy song from heaven, making everyone on the field ecstatic.Shi Hongtu was so excited that the wrinkles on his old face were trembling, he almost didn't cry.

"But the vaccine didn't work out."

This sentence made everyone's joy disappear, and they all looked at Chen Mo, waiting for his explanation.

"We detected two toxic proteins in the patient's blood. It should be the potential toxic protein gene in the mRNA of the vaccine platform system. If this problem is not solved, the toxic protein will accumulate in the patient's body until a certain concentration is reached, and the patient will die. "

"Then next?" Shi Hongtu asked.

"Next, we need to find these two toxic protein genes in the mRNA of the vaccine system platform, and find a way to replace these two toxic protein genes to relieve the toxicity of the vaccine, so that the vaccine can be considered a success."

"Okay, I'll apply to the higher authorities right away, and call a few more genetic engineering experts to help you find the poisonous protein gene." Shi Hongtu said without hesitation, his voice extremely excited.

As long as these two poisonous proteins are found and the vaccine is successfully detoxified, they may completely end this bioterrorism that endangers the world.

They have seen the dawn of victory.

Chapter 500 Convocation

At the Capital Institute of Biogenetics, Wang Haoyi watched the news about the Reedman virus in his laboratory office, thinking from time to time.

This human disaster has lasted for several months, and the worst-hit areas have become unimaginably serious.

It is a pity that his research field is to establish and optimize gene editing technology in hematopoietic stem cells and T cells, study the characteristics of related gene editing technology, improve the efficiency and specificity of genes, and mainly target genetic diseases.

This time the Redman virus belongs to virology, and it is not that serious in China, so they don't need to get involved.

The virus has caused panic in the international community, but there is nothing he can do about it.

After finishing the news, Wang Haoyi put down the newspaper and sighed.It's useless to worry about other things, and doing your own research is the right thing to do.

Boom! !

Just as Wang Haoyi was about to start researching his own project, an old man wearing glasses knocked on the door and walked up to him quickly, looking like he had something urgent to do.

"Director Liu, is there something urgent?"

"Academician Wang, the dean came to inform that Tangshan has made a breakthrough in the Reedman virus vaccine, and is now undergoing urgent technical research, and now needs genomics experts."

Hearing this notice, Wang Haoyi suddenly stood up: "I'll go over."

Before Director Liu could speak again, Wang Haoyi had already started to pack his things and was about to leave the office.

……

Donghai Institute of Life Sciences.

Yang Yunjia quickly entered the laboratory. In the laboratory, there were members of their team, as well as students and assistants.

His team's key research and development plans are precision medicine research projects, epigenomics detection technology and clinical application, and RNA methylation epitranscriptomics sequencing technology, both of which he presided over.

The hot Redman virus outside belongs to immunology, but he is not an expert in immunology and virology, so he was not summoned by the medical team, and Anxin continued to lead their research at the institute.

But just today, the capital came to inform that there was progress in Tangshan's Redman virus vaccine, and experts from genomics experts were needed to participate in urgent technical research.

"Teacher Yang, what happened?" Standing still in the laboratory, other members and students looked at him, and a student asked.

"The capital needs gene editing and genomics personnel for urgent technical research. Yu Jun and Mi Shuangli, you two will come with me."

"Mr. Yang, can you tell me what technology it is?" asked a female researcher named Mi Shuangli.

"The ones at Tangshan Hospital in the capital are analyzing the gene of the Reedman virus vaccine."

"it is good."

The two nodded heavily and agreed without hesitation.

The Center for Disease Control and Prevention issued a convening notice, and experts and academicians in genomics and bioinformatics who are leading research projects across the country did not hesitate to agree to go to Tangshan Hospital in the capital to carry out project research after receiving the news.

In just one day, nearly [-] genomics experts and researchers have arrived in Tangshan.

The staff of the Centers for Disease Control and Prevention and the Ministry of Health are aware of the importance of this project, and they coordinated and quickly mobilized experimental equipment and materials to prepare experimental conditions for researchers.

Tangshan Research Institute.

Chen Mo, Wu Bing, and the team members entered the conference room.

Several team members were surprised to see a room full of people.Some of them have already been recognized, including the experts and academicians of genetic immunology already in the medical team. There are 33 people on the field, almost including the top group of genomics experts and academicians in the country, including their former mentors.

It can be said that a group of people with the most say in domestic genomics are in this conference room.

They were looking at everyone, and the experts below were also looking at them.Seeing the leadership of Chen Mo and Wu Bing, and the extremely young team behind them, many people couldn't help being amazed.

It is this young team that has made great achievements in the two bioterrorism campaigns, and this time it has also made a breakthrough under the circumstances that they are not optimistic about.Seeing that there are students among the team members, some academicians smiled with satisfaction. At least their students are promising, and they are also very proud.

However, compared with Chen Mo who took the lead, it seemed that all geniuses became dim, and everyone's eyes quickly fell on Chen Mo.

In the past, I only heard his name but never saw him, but today I finally saw him.

Chen Mo also scanned the experts and researchers on the field.

Their team can also find the poisonous protein by themselves, but in order to speed up, the more people there are, the faster the speed is obviously.This time, the Center for Disease Control and the Ministry of Health coordinated, supported by the two houses, and found so many researchers, which was beyond his expectations.

After distributing all the materials, Chen Mo walked to the podium in the conference room and directly entered the topic.

"This morning, we conducted another blood test on the patient. You have the test results. The patient has regained initial consciousness. The antibody concentration in his body has increased compared with two days ago, and the number of viruses is decreasing. In theory, after another five days or so, the patient develops resistance to Reedman virus."

After Chen Mo spoke, everyone listened carefully to Chen Mo's explanation. There were many people on the field who were old enough to be Teacher Chen Mo's teacher, but the level shown by Chen Mo was enough to be their teacher.It was under his leadership that the Redman virus vaccine made a breakthrough. No one dared to underestimate Chen Mo because of his age.

Hearing that the vaccine was effective, many people were a little happy, but they were interrupted by Chen Mo just as they were a little surprised.

"But we detected two toxic proteins in the patient's body. These two toxic proteins also increased with the increase of antibody concentration. Just two hours ago, the patient died in pain, and after waiting less than five days He was not killed by Redman virus, but the poisonous protein in his body caused his death.

We preliminarily determined that this toxic protein is caused by the potential toxic protein gene contained in the mRNA of the vaccine platform system.So next, everyone's task is to find these two toxic protein genes in the vaccine, and we will find a way to knock out these two genes to eliminate the toxicity of the vaccine. "

"Academician Chen, is there any drug to degrade these two toxic proteins to achieve the purpose of treatment."

Hearing the interrupted question below, Chen Mo nodded and replied: "We have thought about this method. The medical team is looking for a drug to detoxify the protein, but they haven't found it yet, and it's not a cure for the symptoms."

"Academician Chen, do you have a sample of the toxic protein?" Yang Yunjia, sitting in the first row, asked.

"Yes, we isolated some samples from the patient's blood, but not many. After the project started, the samples of the toxin protein will be distributed to various laboratories. Next, I will explain to you the relevant characteristics of the toxin protein and the expression of mRNA. Relevant information. If you have any questions, you can interrupt me or ask Academician Wu, and we will try our best to answer you if conditions permit."

After the explanation, Chen Mo began to talk about some characteristics of the toxin protein, as well as information related to mRNA, so that they could start researching.

Chapter 501 Disgraceful waste

In addition to Chen Mowubing's original team, more than 30 genomics and bioinformatics experts were divided into two groups, each responsible for the detection of a protein.