Dreaming can be a boss

Now he has begun to set his sights on foreign markets, and there are already teams in charge of translating Xiaomeng, including English, Russian and other languages ​​with the largest number of users in the world. Ye Xun believes that with the excellence and epoch-making nature of Xiaomeng, It will definitely be able to sweep the foreign market, and this is Chaomeng Group's first attempt to open up foreign markets.

As for some foreign opinions saying that Xiaomeng is a big step towards the omnic crisis for mankind, Ye Xun said that he didn't care about it at all. On the contrary, he thought it was a gimmick, which might attract more people to buy it.

And the Xiaomeng 20 version is also under development. I believe that the updated Xiaomeng will be able to attract a large number of users again.

It is precisely because of Xiaomeng's strong competitiveness that Ye Xun simply doesn't know how to describe Su Lu. It is simply "like a hero descended from the sky, really awesome in the world."

However, Su Lu, who is still doing research in the research institute, has no interest in understanding these things from the outside world. His tired body woke up from the container that was temporarily used as the residence of the institute's personnel, but every time he woke up, he knew that he was getting closer and closer to his goal.

In this way, more than 50 days have passed since the research on the gene project.

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"I see! The stem cells are now starting to differentiate! The marker genes have also changed!"

In the silent laboratory, there were only various busy voices, but cheers burst out suddenly.

Standing in front of the monitor, watching the fluorescent marks on the screen undergo microscopic changes, although the electron microscope can allow them to judge whether changes have occurred, but they cannot see how the changes are more intuitive.

Of course, it is enough to be able to judge that a change has occurred.

"What sequence is this?"

"Director, it's No.60 Group Six!" A researcher next to him responded immediately, his face was full of excitement, and at the same time he looked at Su Lu with admiration. In less than a month, Su Lu With his extremely keen judgment and rich knowledge accumulation, Lu made every researcher present admire Su Lu from the bottom of his heart, and he was able to complete a progress almost every once in a while, and it was all related to Su Lu, as if those Difficulties in front of him are not difficult at all.

In the first two weeks, through a series of experiments, it was determined which genes were expressed during the development of human embryonic stem cells.

The embryonic stem cells were bought from other laboratories, and it cost a lot of money. After all, it would take a while to prepare, and Su Lu didn't have the time to wait.As for how to determine which genes are expressed, it is too difficult for other research institutes, but Su Lu wrote a program very simply and crudely, built a model, and because he bought enough embryonic stem cells, The experiment can be repeated many times, and then try your luck, so hundreds of gene sequences for expression are screened.

The human body has a genome with tens of thousands of genes, most of which are "junk dna", and a small number of genes are functional, so most of the researchers at first wondered whether the part of the genes screened out by Sulu had what they wanted Some of them still maintained a skeptical attitude, but Su Lu's screening method had already shocked them extremely.

Just the program and modeling he wrote, once sent out, I don’t know how many people in the research institute will pursue it!

Chapter 286 Rehearsal

After the most difficult first step of the experiment was successfully passed, they continued to start the second research, which was to determine the sequences of those genes, so that they could be labeled later. At this stage, Su Lu once again showed a strong ability, Successfully determined hundreds of gene sequences, but only took three weeks.

This one-handed operation has completely conquered the researchers of the institute. In their eyes, Su Lu's ability in genetic engineering is completely better than those professors they know. It's not 01:30. This is different from knowledge reserve, but professional technology ability and practical ability to knowledge.

At least these researchers say they may not be able to do it in their lifetime.

In the remaining time, it is to find genes that can be differentiated and expressed through the determined sequences.

Now they have found that the stem cells at this time are in the process of differentiation, that is, the process of gradually producing cells with different functions, shapes and characteristics.

A researcher said excitedly: "Director, what shall we do next?"

Su Lu said calmly: "Transfer No.60 group six, continue to cultivate, and observe in which direction it is going to differentiate. I want to determine whether one gene controls all the differentiation processes, or one gene controls each differentiation process. process."

The other researchers all responded, and immediately took action.

"Continue to observe the remaining groups to determine whether there are genes for differentiation. New Year's Day is coming soon, and we will try to finish it before the holiday. Please go to a big meal on New Year's Day!"

"it is good!"

Su Lu's words were undoubtedly very inspiring, and all the researchers immediately became motivated. After all, not only can they have a holiday, but they can also have a big meal.

What's more, the current research is what interests them the most, and they probably won't care even if the sky falls.

Seeing that everyone continued to work hard, Su Lu smiled slightly. Everything was proceeding in an orderly manner as he had predicted in his dream.

He is very clear that different differentiation processes are determined by different genes. Once these genes are determined, they can be artificially expressed separately, and then placed in the same culture medium as the recipient's internal environment to develop Adult human organs.

And this kind of organ can be directly transplanted into the recipient's body without immune rejection, because the gene that Su Lu found can cause stem cells to differentiate by directional induction of its expression, and then cultivate a An organ that does not produce a rejection reaction with the recipient's leukocyte antigens.

On a deeper level, there are still many questions, such as why the gene can make the differentiated organs not have an immune reaction with the human body, etc., all need further research, but Su Lu doesn't need to worry about these anymore, he All you need to know is that you have successfully solved all the problems of getting started.

According to the current progress, human organs will be able to be cultivated in May next year, but because there are no experimenters, the most important point is not sure, that is, whether there will be accidents after transplantation into the body, but it can also be passed through experiments. To determine whether immune rejection will occur.

After that, it is to pass the application and start the clinical trial. This also needs to find patients who are willing to cooperate, but the probability of finding it is still very high. After all, there are too many patients in Huaxia who suffer from organ diseases and have no money to treat them. There are too many terminally ill patients, and there are definitely not a few patients who are willing to take a gamble as experimenters in order to survive.

But in short, Su Lu is sure to cure them.

"But now we have to start thinking of ways to reduce the costs related to cultivation."

Su Lu looked at the positive scene in the laboratory and pondered in his heart.

His original intention is not just to find a way to cure organ diseases, but to allow patients with this disease to be treated, but the cost of growing an organ is quite high, Su Lu must find a way to reduce this cost, at least First control it below 5 yuan or even four digits, otherwise it will be a problem that patients cannot afford it.

"So it is necessary to design a device that can be mass-produced to extract patients' cells and cultivate stem cells."

It is not necessary to be embryonic stem cells, including pluripotent stem cells, and pluripotent stem cells are obviously much more convenient than embryonic stem cells. After all, embryonic stem cells have to consider ethical issues.

Although there are already many methods on how to obtain pluripotent stem cells, those methods all cost a lot of money. Su Lu estimates that he can start the second task at the same time, which is to study how to transform somatic cells into pluripotent stem cells Methods.

This is also one of the existing studies, and has achieved a lot of results, but it also requires a lot of cost.

"It doesn't matter, it's done."

Although there are many difficulties, for Su Lu, it is basically a matter of time.

"The big deal is that I will lose my energy in the next few years. It doesn't make me a person who touched China, which is a bit unreasonable."

Thinking of this, Su Lu smiled, and said happily, of course, if the government really awards him this award, it is not impossible.

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Time passed quickly, and on the day before New Year's Day, they successfully discovered that there were seven genes that could control the differentiation process in those hundreds of experiments. As for what exactly controlled the differentiation process, further research was needed, but no matter what How to say, the current results have made every member feel very excited.

And in a research institute, these news naturally cannot be concealed a lot. Although at the request of Su Lu, every researcher who participated in the research strictly kept his mouth shut and did not disclose it to any non-project members, but Just hearing those cheers from time to time is enough to arouse various speculations from others.

Those professors all expressed their curiosity about Su Lu's research. They don't know how far he has researched. Moreover, Su Lu promised to ask them relevant questions at the beginning, but there has never been any movement until now, which makes them even more surprised. .

Su Lu didn't hide it, and introduced the current results generously. These professors were all selected by him before being invited to the institute. Their character is guaranteed, so don't worry, so these professors know that this research has actually been completed. When I reached this point, I couldn't help being surprised, and then regretted not participating in it because I didn't trust Su Lu's ability at the beginning.

It's just that at this time, if you open your mouth and want to join in, it seems like you want to take advantage of it. These professors can only express their congratulations, and then hint to Su Lu in various words in their words. If you have any problems, you should contact them. After the project is completed in the future Finally, it is also a good thing that their names are mentioned in the paper.

To this, Su Lu did not respond. Of course he has his own ideas. As long as he personally leads this project and gets a corresponding reputation, it will also be helpful for other projects in the future, because at that time others You need to have more trust in his research, even the country may give him various resources.

So it can only make the professors feel sorry for themselves.

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In this way, the time came to mid-January 2022.