my life simulator

In the next month, there will be hundreds of cancer patients around the world who survived due to Lu Li's new technology.

All of a sudden, Lu Li and his T cell gene editing technology received widespread attention from the medical community, and also had a huge impact on society.

"Lu Li, a young scientist in our country, has opened a new chapter in the fight against cancer!"

"Lu Li invented a new technology to treat cancer. It doesn't require radiotherapy, chemotherapy, or even surgery."

"Genes are the future. From Lu Li's T cell gene editing technology, let's talk about the impact of genetic engineering on human beings."

"How far are we from conquering cancer? Lu Li tells you that this day is just around the corner!"

There were news reports about Lu Li in newspapers, on TV, everywhere.

On the campus website of Fudan University, there was even a floating good news: "Congratulations to Lu Li, a student from our school, who has made a breakthrough and major research achievement in CAR-T technology!"

This wave of anti-cancer new technology has also spread to Xichuan and Yucheng.

When Xichuan TV Station and Yucheng TV Station learned that Lu Li was one of their own, the publicity became even more lively.

"News from our station: Lu Li, a young scientist in my country, has made major scientific achievements in the CAR-T anti-cancer technology and created a new technology for cancer treatment."

"Lu Li, from Xichuan Yucheng..."

Lu's mother, who was selling vegetables in the vegetable market, raised her head in surprise and looked at the TV screen hanging on the wall.

Land from?my son?

My son turned out to be a scientist?

Lu's mother rubbed her eyes, looked at it for a while, and found that the photo on the TV was Lu Li and her son.

Some time ago, my son sent some money to the family, saying that he was going to Fudan to study as a graduate student.

Now... turned into a scientist?

After standing blankly for a while, Mother Lu burst out laughing "again" and began to show off: "My son! This is my son! My son is a scientist!"

"Sister-in-law of the Lu family, your son is actually a scientist? That's amazing!"

"Yes! Yes! Scientists! It's amazing!"

The people around were full of envy and admiration.

Afterwards, Mother Lu's food was given away again.Lu's father called friends and friends to set up wine and treat guests again.

Uh...why do you say "again"?

……

"Xiao Lu, congratulations!"

Professor He put down the newspaper in his hand, and the headline on the newspaper was Lu Li's photo.

"Thank you!"

Lu Li smiled and said, "CAR-T technology is still immature, and the praise from the outside world is a bit exaggerated."

"Don't underestimate yourself!"

Professor He said with a smile: "Your improved CAR-T technology is currently one of the most effective means to fight cancer."

Having said that, Professor He glanced at Lu Li, and continued, "You have made major scientific achievements. I talked with Dean Jiang, and we both felt that your knowledge level and scientific research ability have surpassed the level of graduate students. .So, you can graduate."

"what?"

After only one year of graduate school, can you graduate early?

"Graduate and doctoral students, in fact, there is no strict requirement for the time of study. As long as your knowledge level and scientific research ability meet the standards, you can graduate."

Professor He explained with a smile, and then asked Lu Li, "After you get your master's degree, which direction do you plan to study for a Ph.D?"

"Of course I will continue to study with you!"

Lu Li felt that the cooperation with Professor He was very pleasant, and he didn't bother to find another tutor. It would be more convenient to continue to study under Professor He.

"This one……"

Professor He hesitated for a moment, and said, "Of course I'm very happy that you continue to study with me. But...your research direction is mainly genetics, and I'm afraid I can't help you much in this regard."

"Don't say that, I still have a lot to learn from you."

Lu Li has copied the knowledge of countless professors, and his knowledge accumulation is already very rich.

For Lu Li, what he needs is not knowledge guidance, but various conveniences in scientific research.

Therefore, Professor He, who gets along very well, is the most suitable tutor.

"OK then!"

Seeing that Lu Li was very willing to continue his PhD with him, Professor He didn't object, "You prepare. At the end of the semester, you will take the exam with the graduates of this year and prepare a graduation thesis."

"Ok!"

Lu Li nodded in agreement.

After leaving Professor He's office, Lu Li returned to Binjiang Garden.

Sitting down in the study and turning on the computer, Lu Li was about to prepare his graduation thesis when he suddenly saw hundreds of emails appearing on his e-mail.

"Why are there so many emails?"

Lu Li hastily clicked on the email.

Some of these e-mails are exchange and discussion e-mails sent by scholars from various domestic research institutions and doctors from various cancer hospitals.

Some of the emails turned out to be cooperation invitation letters from various companies, and even invitation letters from biopharmaceutical companies.

The remuneration is very high, but it's a pity that Lu Lizhi is not here, and he doesn't need to hug the thigh of the "financial father", so he doesn't bother to pay attention.

To Lu Li's surprise, there were also invitation letters from some research institutions around the world in the email, inviting Lu Li to go to exchange and discuss.

In these invitation letters, there is an exchange invitation from the American Cancer Society.

"An exchange invitation from the American Oncology Society?"

A smile floated on Lu Li's face, "Is this sent to your door for me to copy the knowledge?"

In terms of cancer research, the American Oncology Society does have profound accumulation.These accumulations are also very valuable for Lu Li's research on the technology to overcome cancer, and it is worth copying.

It's just that... Lu Li has no intention of going to the United States for an exchange at the moment, so let's talk about it after getting a master's degree!

After replying to some important emails in the mailbox, and leaving the other emails alone, Lu Li closed the email box.

After getting up and walking out of the study, Lu Li lay down on the sofa, closed his eyes, and opened the virtual laboratory again.

There are still two months until graduation season.

Lu Li wasn't worried about the graduation exam at all.It's just that... the graduation thesis needs to be spent on.

If you just deal with it, the graduation thesis is not difficult.However, Lu Li had been hailed as a young scientist before, so naturally he couldn't fool around with a graduation thesis.

Let’s continue researching from CAR-T technology!

Last time, Lu Li lowered the intensity of the immune response by modifying the genes of the T cells, reducing the chance of the human immune system going crazy.

This genetic modification is very safe.Because after the T cells complete the task of killing the enemy, they will quickly self-destruct and will not exist for a long time.

Now, what Lu Li wants to modify is another type of immune cell - dendritic cells.

Dendritic cells are intelligence agents in the immune system, which will quickly transmit the information that the human body is attacked by viruses to the immune system, triggering a severe immune response in the human body.

Under normal circumstances, dendritic cells, the intelligence agents, are extremely beneficial to the human body, and they are the key to the human body's resistance to virus invasion.

However... In CAR-T technology, in order to prevent the immune system from going crazy, weakening or even shielding the intelligence ability of dendritic cells is more valuable for treatment.

However, dendritic cells are long-lived and do not self-destruct.Once the intelligence ability of dendritic cells is modified, the immunity of the human body will be reduced.

This made Lu Li a little confused.

Once the genes of dendritic cells are modified and their intelligence capabilities are weakened, it may be possible to reduce the chance of the immune system going crazy and allow T cells to successfully kill cancer cells.

However...if the cancer stabilizes and won't get worse, but the patient dies because of a cold, how can it be justified?

Let's experiment first!

Human experiments that cannot be done in reality can be done at will in the virtual laboratory without taking any risks at all, which is very convenient.

Next, Lu Li began gene editing on dendritic cells.

It also uses cutting protein to cut the DNA chain of dendritic cells, shielding the "intelligence ability" of dendritic cells!

Experimentation is trial and error!

The advantages of the virtual laboratory are very obvious.

There is no consumption at all, and there is no need to burn money at all. No matter how expensive the experiment is, it can be done openly.

One day, two days, one week, two weeks.

Lu Li conducted countless experiments, and finally identified the "gene fragment" of dendritic cells representing intelligence capabilities.

After finding the target, it is convenient to operate.

Transcriptase marks the gene fragment, and injects it into dendritic cells together with the splicing protein, and successfully prepares a dendritic cell that shields the intelligence ability.

And then... Lu Li started experimenting on humans.

After injecting this dendritic cell, which has shielded intelligence capabilities, into the experimental body, Lu Li began to observe the reaction of the experimental body.

And then...no response.

After testing, Lu Li found that the dendritic cells injected into the experimental human body did not divide or proliferate, and he was a "quiet handsome man".

A dendritic cell without intelligence ability has no effect on the human body at all.

Is it necessary to modify all the dendritic cells in the human body?

There are 60 trillion cells in the human body, even if there are not many dendritic cells, they are calculated in billions.This workload... When the patient dies, the dendritic cell modification task has not been completed.

This road is completely unworkable!

Lu Li heaved a long sigh, it really wasn't that easy to handle.

wrong!My train of thought is wrong!

If you don't want to answer the phone, why do you want to shut down China Mobile?Can't you just turn it off?

So, Lu Li set his target on another type of immune cell.

B cells!

If T cells are the frontline troops, B cells are the logistics and command.

Since the intelligence ability of dendritic cells cannot be shielded, B cells should be shut down so that they cannot receive the "call" from dendritic cells.

B cells, the logistics and command center, cannot receive information from dendritic cells, so naturally they will not produce an immune response, will not release immune factors, and will greatly reduce the madness of the human immune system.

More importantly, B cells, like T cells, will self-destruct after the battle, leaving only a very small number, stored in lymph nodes, and most B cells will not exist in the human body for a long time.

So... modifying B cells is the right direction.

Thinking of this, Lu Li immediately started to act.

It took another month for Lu Li to map out the gene fragments that B cells receive messages from.

Here lies the hardest part of genetic modification.Humans still know too little about genes. 30 billion base pairs, it will take a long time to read them all.

After finding out the gene fragments for B cells to receive messages, Lu Li used splicing proteins to modify the genes of B cells, blocking the ability to receive messages.

Finally, a genetically modified B cell was produced!

Chapter 357 Have You Overcome Cancer?

After preparing this B cell, Lu Li immediately started experimenting on humans.

This is again a huge advantage of virtual labs.

If it is a normal experimental procedure, experiments must be carried out on various small animals first, and after a long period of time, it is possible to conduct human experiments.

Even... Many scientific research projects have no chance of being approved for human experiments.

Lu Li was different.

In the virtual laboratory, everything is virtual, and everything is fake.He can do human experiments at will, and do whatever he wants, without any restrictions at all.