From small clinic to medical empire

Chapter 261 On how to get venture capital without being wiped out
"The latest technology from the Roslin Institute?"

Zhang Zifan smiled, "Does the Roslin Institute have any new technologies?"

Campbell was stunned for a moment, thinking that this young Asian must not be a playboy, right?

But even if he is a playboy, he is an angel investor that Campbell can't afford to offend today. He patiently explained: "Mr. Zhang, you may not know the Roslyn Institute, which is one of the halls of life sciences..."

"Okay, okay, Mr. Keith Campbell, I have heard your story when I was a student, otherwise I would not have gone all the way to find you to discuss cooperation..."

Zhang Zifan paused and thought about the words, "Or hiring, I'm not as petty as Lord Knight Wilmut, but for our cooperation, I think you should know the priorities."

Hearing Wilmut's name, Campbell's complexion changed drastically. For a moment, Zhang Zifan noticed that his fingers were tightly clenched together, trembling non-stop.

"Your value to Haoran Medical lies in your proficiency in cell biology technology, and in return, we will give you a chance to prove yourself again."

Zhang Zifan stood up from his seat, walked slowly behind Campbell, and whispered like a devil, "Don't you want to take back what you lost with your own hands?"

……

[Advanced reception room] was contracted and constructed by Ma Qianqiu Studio last month.

As a very rare high-level building, [Advanced Reception Room] has two very outstanding features.

[Guests follow the host: Guests who are invited to this reception room as guests, the probability of agreeing to the host's request increases by 30%]

[Open and honest: Guests who are guests here will temporarily forget about thick black studies, and it will be easier to reveal their own feelings]

Therefore, when Campbell heard Zhang Zifan's whisper, he could no longer suppress his emotions and stood up abruptly: "Of course! Step on it!"

Although influenced by the [Advanced Reception Room], Campbell still had reason and did not blurt out the word old woman.

After all, Queen Elizabeth still has a special meaning to an Englishman.

Of course, Campbell is a Scot, and even silently voted for it in the independence referendum some time ago.

But he is a scientist after all, not a political figure, so Campbell doesn't want people to know his views on the Queen.

After a moment of excitement, Campbell suddenly became depressed. He shook his head and said: "But cloning technology has..."

"Cloning is dead!"

Zhang Zifan answered with a smile and patted Campbell on the shoulder, "The research prospects of cloning technology are functionally dead, and they are buried underneath. Are you surprised or surprised?"

"what!"

Campbell jumped up in surprise, "You are Shinya Yamanaka? Why are you so young? Are Asians really immortal?"

puff!

As the deputy dean in charge of scientific research, Yang Tingting also watched the whole process in the living room.

She had been silently watching Senior Brother Zhang pretending to be aggressive, but now she couldn't bear it any longer, she covered her stomach and laughed, "Senior Brother, it turns out that Ning is also Japanese, so let's act like the Emperor is furious?"

Zhang Zifan twitched his lips in embarrassment.

"I'm Chinese, how could it be Shinya Yamanaka, haven't you paid attention to academia recently?"

Campbell froze.

Since he ran back to his hometown to hide from debts six months ago, he has not had any contact with mainstream academic circles.

However, things that have been attached to for half a lifetime cannot be put down just as easily.

Although unable to participate in academic exchanges, and even unable to browse academic journals because he could not afford the Internet fee, Campbell still learned some new news through several scientific channels on the radio.

At this time, he finally remembered the news from a month ago.

"In a mysterious oriental hospital, former car king Mike Schumacher received neuron directional induction reinjection surgery and achieved good results, and can now communicate normally with his family..."

……

Although from a scientific point of view, the technique of neuron-directed induction and reinjection is not as universal and forward-looking as Shinya Yamanaka's pluripotent stem cell induction differentiation technique.

However, as the pioneer and practitioner of the first mature somatic cell re-induction therapy, Zhang Zifan's contribution is definitely not much lower than that of Yamanaka Shinya.

This is why once Wang Bin confirmed that Schumacher's treatment was effective, he supported Zhang Zifan's research at all costs.

Therefore, there is really nothing wrong with Zhang Zifan claiming to be one of the gravediggers of cloning technology.

After Campbell figured out the cause and effect, he looked at Zhang Zifan with extremely complicated eyes.

He had no doubt that Zhang Zifan achieved such an achievement by himself.

Because he himself successfully broke through the barriers of mammalian cloning technology at Zhang Zifan's age.

Boyhood is often the golden age for scientists to invent and create. As time goes on, scientists may gradually improve their technical level and sharpen their vision, but their ability to innovate will gradually decline.

Gauss solved the series summation problem at the age of 9,
Libby started doing chemistry experiments at the age of 11,
Maxwell published a paper on mathematics at the age of 14,
Galileo discovered the principle of the pendulum at the age of 17.
Garrobi proposed group theory when he was 17 years old.
Birkin invented aniline at the age of 18,
Edison received his first patent at the age of 21.
Newton founded the calculus system at the age of 23,

Heidelberg established quantum mechanics at the age of 24,
Einstein invented special relativity at the age of 26,

Li Zhengdao and Yang Zhenning jointly discovered the law of non-conservation of parity at the age of 29 and 34 respectively...

In short, scientists cannot judge their abilities by age.

Campbell could tell at a glance that Zhang Zifan was not a human being. He was not an ordinary person. He was just like those brilliant names in the history of science. He was an extraordinary young genius.

but,
Originally I could do the same...

Campbell looked at the heroic Zhang Zifan, his eyes full of his own shadow from 20 years ago.

At the same time, after finally figuring out what kind of emerging medical group he had joined, Campbell's desire for revenge gradually rekindled.

"Mr. Zhang, I am honored to work for you, but I have to tell you honestly that I have been dealing with somatic cell cloning technology all my life.

When I reach my age, as a scientific worker, my technical ability may be more solid, but my innovative thinking has gradually dried up.

In the past 20 years, I have accumulated a lot of ideas that I think are very valuable.

However, due to the subsequent exhaustive efforts of Huang Yuxi and others, my original ideas were already taken advantage of by them, and even if they had not, under the impact of the new technologies of you and Yamanaka Shinya, those ideas of mine had long been of no value.

after all……

You're right, cloning is dead..."

At this point, Campbell couldn't help but smile bitterly. He hadn't realized it before, but now that he thought about it carefully, he seemed to be incompatible with Asians. Top scientists from China, Japan and South Korea had tortured him all over, intentionally or unintentionally.

Of course, the more direct target of these three talented Asians is the old enemy Wilmut, who is still relying on Dolly the sheep to make money and clinging to cloning technology.

Campbell had imagined Wilmut's face more than once when he heard the breakthrough in somatic cell induction technology.

After all, compared with somatic cell cloning technology, the advantages of somatic cell induction technology are too huge.

Even Campbell, the true "Father of Dolly", can't see the possibility of a comeback in cloning technology at all.

"Haha, that's right, cloning technology is already socially dead, but... I dug it out again!"

Zhang Zifan pointed to himself and said, "You have to know, I am a doctor, and then I am a scholar.

Whether it is technology or people, his corpse is an endless treasure trove for doctors, and as long as the appropriate technology is used as a medium, the parts of these corpses can be used to play new roles in the torsos of other lives. "

"What do you mean?"

Campbell frowned, "Are you saying that cloning technology can be used in the induced differentiation of somatic cells? But these are two completely incompatible systems, right? Forcibly twisting them together will only add to the liking!"

Since the birth of Shinya Yamanaka's pluripotent stem cell induction technology, it has attracted the attention and research of scientists from all over the world.

Naturally, there are many scientists who attempt to combine cloning technology with it.

As far as Campbell knew, the Collins Institute under the leadership of Wilmut had made many attempts in this direction, but all ended in failure.

The craze quickly faded after that.

After all, since somatic cells can be induced to re-differentiate into stem cells, stem cells can also be induced to become various somatic cells.

So the cloning technology, which mainly replaces the nucleus of the fertilized egg to form embryonic stem cells, is completely superfluous.

Not to mention, now that Zhang Zifan's team is the first to achieve neuronal differentiation induction to treat neurological diseases in clinical practice, cloning technology is even less valuable.

So Campbell looked at Zhang Zifan doubtfully, with questions in his heart.

"Haha, let's talk about this later."

Zhang Zifan smiled and said, "After you come, Lao Kan, the entire backbone of our Haoran Medical Group Biotechnology Company will be here. We will have dinner together in the evening, and we will talk while eating."

……

It is a Chinese tradition to discuss projects at the dinner table.

Now that Campbell is on a pirate ship, he can only do as the Romans do.

Haoran Medical Group Biotechnology Company is an important piece of the jigsaw puzzle for Zhang Zifan to build a medical empire.

Originally, according to Zhang Zifan's own ideas, the ultimate medical empire should be a large-scale complex covering clinical treatment, teaching and training, basic research, R&D and manufacturing.

At least it must be like Ali's dream town to form a large-scale medical industry ecological community.

From hospitals to schools, from schools to school-run enterprises... The order of such industrial development should be step-by-step.

However, the appearance of the eldest and the youngest of the Li family, an alternative infertility patient who is not stupid, changed things a little.

After Zhang Zifan carefully explained the technical difficulties, focusing on the huge difference between "having a child of one's own" and "having a clone of one's own body," Li Jiaxian also realized that the matter was difficult.

Yet he didn't give up.

Many people joked that their family has no throne to inherit, so it doesn't matter whether they have children or not.

Of course, the Li family does not have a throne to inherit, but they do have a lot of assets to inherit.

Li Hongda, the king of Xinan hardware, emerged in the 89s and [-]s and began to transform into other industries in the past ten years.

The Li family's family assets are approximately 35 billion yuan, making them one of the richest people in Xinan County.

35 billion yuan sounds like a lot, but in the field of biomedicine, it is actually stretched.

Multinational medical companies develop a new drug casually, and the cost is more than 100 billion.

Rich companies like AstraZeneca spend an average of an astonishing $118 billion to develop a new drug, equivalent to RMB 825 billion!
This amount of money is enough to squander two Dushan counties!
It is equivalent to a semi-aircraft carrier battle group and a semi-Beidou system.

So when Li Jiaxian asked if he could help solve his problems if he invested 5 million yuan or even 10 billion yuan, Zhang Zifan smiled unkindly.

This made Li Jiaxian a little baffled.

But after all, he is a very active young man. After returning, Li Jiaxian used his contacts to inquire about relevant news.

I don't know if I don't ask, I'm startled when I ask.

The money-burning speed of this medical creature made the son of a local tyrant in Xinan feel like a pauper for the first time.

I, and my father, the so-called peasant entrepreneur, are not even a loach in front of these multinational technology giants.

Li Jiaxian, who recognized the facts, was disheartened and called Zhang Zifan to apologize.

Unexpectedly, Zhang Zifan extended an olive branch at this time.

He is willing to sign a gambling agreement with Li Jiaxian.

That is, Haoran Medical invested in technology and land instead of establishing a joint-stock biotechnology company.

However, Haoran Medical needs to account for 95% of the total equity.

However, Li Jiaxian personally invested 10 billion yuan and can only hold 5% of the shares. He only enjoys dividends and has no decision-making and management rights.

Such a proposal can be said to be quite harsh.

However, according to the VAM agreement, if Haoran Biotechnology Company cannot realize assisted reproductive technology for patients with azoospermia within 10 years, then its 45% shares will be automatically transferred to Li's party.

……

The entire equity design was carefully considered by Lao Fang after consulting with Erich.

Although it looks fancy, there is only one core essence.

That means Zhang Zifan wants to have sex for free!

That's right, prostitution.

After returning home, Zhang Zifan thought over a question over and over again.

If there is a bully who is willing to offer 10 billion in scientific research funding, should I refuse it?

The answer, of course, is no.

Regardless of whether the final experiment is fruitful or not, and whether the results can be used clinically, we will have to prostitute him for ten years before we talk about it.

This is not shameless, but an inevitable law of scientific research.

The results of any investment in scientific research are unpredictable.

Dozens and tens of billions are invested in research, and the results are all in vain.

Today, Zhang Zifan prostituted Xiao Li with 10 small goals for nothing. In the future, he might be able to pay him back a child plus a sky-high annual dividend.

You know, according to the data of the China Women's Federation, the number of infertility patients in the country has reached a staggering 6000 million, and on average, 10 in every 1 couples suffers from infertility.

Although technologies such as artificial insemination and in vitro fertilization are mature, they can help many couples solve unspeakable secrets.

For example, patients with low sperm quality and insufficient quantity can have their own children through these artificial reproductive technologies.

But even the third-generation test tube technology with the best effect is still ineffective for a class of patients.

That is the situation where the man has very few healthy sperm, or even no sperm.

If you look at the remuneration for sperm donation in various organizations that has risen a lot every two years, you can know how big the potential demand in society is.

however,
However, for a normal person to use other people's sperm to impregnate his wife, there is always a hurdle in his heart.

Or it can’t be said to be a hurdle, it can be said to be a natural chasm.

In many cases, such couples would rather adopt than choose artificial insemination with donor sperm.

But even so, healthy sperm is still in short supply in the medical market.

If there is such a technology that allows them to have their own children in the true sense, even if they need 20, 100, or [-] million in treatment fees, they will definitely not hesitate.

Therefore, Zhang Zifan's focus on this research is not so much to help Li Jiaxian, but rather to aim at an untapped virgin land in the medical market.

It's just that with successive leaps and bounds, the funds on Haoran Medical's books have gradually dried up.

If it is a normal venture capital investment, no matter how fanciful Zhang Zifan's words are, capital will definitely ruthlessly take away most of the equity.

But from Li Jiaxian's side, taking advantage of his eagerness to seek a child and adding a seemingly fair gambling agreement, Zhang Zifan can obtain start-up funds for leapfrog development at a very small cost.

(End of this chapter)