Doctor Song, are you married?

Chapter 423

In the laboratory of Renai Hospital, Liang Zi wore dark brown rimless glasses, which actually made his slightly wretched face look more handsome.

Song Qi sat in front of the experimental table and looked at Liang Zi who was busy under the microscope. He thought to himself that it seems that these Yingying Yanyans in the public relations department of Renai Hospital really don't get their salary for free. With such an order, he originally looked at Liang Zi, who makes people's hair stand on end, actually looks seductive.
"Song Qi, please wait a moment while I complete the genetic analysis of this patient. I will do it very quickly."

Song Qi came to him in person, which made Liang Zi very excited.

Song Qi came to him. She must have research on gene therapy that she wanted to discuss with him in person. Thinking that the challenging work he had been waiting for for a long time was about to come, Liang Zi was very excited.

If he hadn't had work on hand, he would have rushed to Song Qi and given her a big hug.

Song Qi nodded towards him, "Don't worry, take your time, I'll look around first." After saying that, he started touring the laboratory.

The hardware facilities of the Renai Hospital laboratory are absolutely unparalleled. Just looking at the floor space of the laboratory, it is much larger than the laboratory of the People's Hospital. The decoration is extremely elegant, with a mirror-white experimental table and bright and dazzling marble. Not to mention floor equipment, microscopes, and spectrum analyzers, they are all big brands and the most advanced models. The equipment in the laboratories of top foreign hospitals is no more than this.

Song Qi came here this time to inspect the laboratory of Renai Hospital and discuss with Liang Zi the genetic analysis and treatment of family hereditary aplastic anemia.

He was still interested in the genetic disease in Scarlett's family.

Song Qi smiled, it seemed that Liang Zi was more anxious than him.

"No, no, no, I haven't done much research on gene therapy. However, I am very interested in this area. I have done some research recently and have an immature idea. I don't know if it makes sense, so I came here. Let’s discuss it with you,” Song Qi said.

"This idea is rather strange, can you elaborate on it?" Liang Zi also became interested and sat down opposite Song Qi.

"The main reason is that the equipment is great. Of course, my skills are also great!" Liang Zi smiled confidently and got up to wash his hands at the sink.

"It's like this. Scarlett briefly described to me the illness in her family that day. Scarlett and Scarlett's mother both had the disease at an earlier age, and it came violently. Scarlett's mother lost her life directly, and Scarlett almost died. The child died as a result. However, Scarlett's uncle was able to survive well into his fifties under temporary treatment with hormone replacement therapy. Does this mean that the gene expression of this disease is deeper on the X chromosome than on the Y chromosome? "Song Qi expressed his thoughts.

"I came here today mainly to ask you some questions." Song Qi said.

"Doctor Song, when will Miss Scarlett's family come to the hospital?" Liang Zi asked Song Qi while washing his hands.

"So fast?" Song Qi also stood up.

Doctors always focus on treating illnesses and saving people. Let these little disturbances pass away in the wind.

However, regarding the genetic research on familial hereditary aplastic anemia, he did not do much research other than the information provided to him by the system. Therefore, before starting the project, he felt that he needed to come to the laboratory to prepare lessons. , listen to Liang Zi’s experience, and by the way, smooth out your own thoughts.

"What do you think? Tell me!" Liang Zi is also not good at words, but when he heard Song Qi talk about work, he became interested.

Although Scarlett had offended him by asking him about his height, weight and measurements, in view of the misunderstanding, Scarlett sincerely apologized to him, and he could forgive her a lot.

"Have you ever considered whether the genetic loci of family hereditary diseases are not only on the autosomal chromosomes, but also on the sex chromosomes?" Song Qi got straight to the point and revealed a question that he had been thinking about for the past two days. question.

Liang Zi is naturally the best candidate.

"Is there such a thing?" Liang Zi was a little surprised.

"Dr. Song, my genetic analysis has been completed. The equipment in our laboratory is advanced, and the results are so smooth. I don't know how many times more powerful than the equipment when I was studying for a Ph.D.!" Liang Zi has experimental data. , quickly stood up and said excitedly.

After Scarlett told him about the situation of his uncle's family, Song Qi did some homework, read a lot of literature, and gained some insights of his own.

However, he really didn't have much experience in gene therapy, so he thought it would be better to find an expert to discuss it.

"Please tell me? Doctor Song, please stop joking. I am the experimenter, and the main treatment plan is still with your doctor." When Liang Zi heard this, he thought Song Qi was joking.

Song Qi has always kept up with Ah Q's spirit.

"According to previous studies, the gene loci for familial hereditary aplastic anemia are all on autosomal chromosomes, and the gene loci are relatively clear, and the gene fragments are not difficult to extract. However, the situation you mentioned seems to be There is some truth to it. How about we collect Uncle Scarlett's blood for genetic analysis first? "Liang Zi is a scientific researcher and always relies on experimental data to speak, never make blind assumptions.

"He hasn't come to me yet. When he comes, I will ask the nurse to collect the specimens and send them over." Seeing Liang Zi in such a hurry, Song Qi said quickly.

"One more question, can you undergo gene replacement?" Song Qi asked again.

I came to Liang Zi today. He had prepared a lot of questions.

"Gene replacement? Doctor Song, do you have such a big appetite?" When Liang Zi heard that Song Qi mentioned gene replacement, he suddenly became excited, like a hungry wolf seeing a little white rabbit.

"Since you have to do something, you have to do your best!" Song Qi smiled.

"Of course, I also know that this is difficult at the moment, but you still have to have a dream. What if it comes true?"

Although Song Qi had not been involved in gene therapy much before, he had done a lot of homework in this area since taking over Scarlett's disease.

There are many gene therapy strategies at present. To sum up, there are just a few types.

For example, gene repair is to correct the abnormal part of the disease-causing gene, retain the normal part, and ultimately completely restore the disease-causing gene.

For example, there is also memory modification, also called gene supplementation, which is to introduce the target gene into diseased cells or other cells. The expression product can strengthen or correct the defective cell function. This is the method Liang Zi used when he treated Scarlett with blood transfusion. , this method is currently used more clinically, but it also has limitations, that is, the defective gene still exists.

There is also a method called gene regulation, which introduces the genes of antibodies, antigens or cytokines into the patient's body to change the immune status and achieve the purpose of preventing and treating diseases. For example, interleukin-2 can be introduced into tumor patients to increase the level of IL-2 and activate the anti-tumor activity of the immune system in the body to achieve the purpose of preventing and treating tumors. Song Qi extracted stem cells from Scarlett's child and used this method.

However, although these methods have certain therapeutic effects, the problem genes still exist.

Gene replacement is different. This is a treatment method that replaces the disease-causing gene with a normal gene in situ, completely restoring the DNA in the cell to normal. This is the most ideal gene therapy method. However, according to Song Qi's understanding, many experts are currently doing research in this area, but the results are minimal.

"Song Qi, to tell you the truth, I did research in this direction with my supervisor for a period of time, but it was too difficult. My supervisor did it for five years, and I followed him for three years. Later, due to funding, It was insufficient and the results were not obvious, so we shelved the project." Liang Zi was quite sad when talking about this past event. "I can give you an idea, you can try it."

Gene therapy is a high-tech biomedical technology that introduces normal human genes or genes with therapeutic effects into human target cells in a certain way to correct gene defects or exert therapeutic effects, thereby achieving the purpose of treating diseases. It targets the root cause of the disease - the abnormal gene itself. Currently, there are two forms of gene therapy: one is somatic cell gene therapy, which is widely used; and the other is germline gene therapy, which can cause genetic changes and is limited.

"Doctor Song, tell me quickly!" Liang Zi leaned forward. He really loved scientific research from the bottom of his heart.

"Can you try to start with the germ cells? Just like the question I just told you, the gene expression of disease genes on the X chromosome is different from the expression on the Y chromosome. Try to combine these two points. For a moment, right?"

Before Song Qi finished speaking, Liang Zi slapped his thigh suddenly, "Doctor Song, you are really my lucky star. You came here today and every word you said was so precise that it made me realize, no, I'm going to go right away." Let’s do an experiment.” After Liang Zi said this, he stood up suddenly and walked straight to the experimental table.

Song Qi shook his head helplessly, "You don't have to be so anxious. I don't know much about gene therapy. I just imagined it wildly. Whether it can be realized depends on your professionals."

Liang Zi, who had just sat down in front of the experimental table, suddenly turned red when he heard this, "Dr. Song, you are slapping me in the face by saying that. If you don't understand gene therapy, who are we people? Don't worry. Look, I studied for three years for a master's degree and three for a doctorate. My six years of scientific research results are not as valuable as what you just said. Those words you just said really inspired me. I have many ideas in my mind now. I want to Once verified through experimental methods, Dr. Song, wait for me for a few days, three days! If you wait for me for three days, I will definitely give you a result that satisfies you!" Liang Zi said, no longer talking to Song Qi, but He concentrated on getting busy on the experimental table.

Seeing that Liang Zi was concentrating on his work, Song Qi couldn't help but shook his head with a wry smile, "I had an idea originally, but it seems I'll talk about it next time."

However, there will be many opportunities for cooperation in the future, and it will be time to talk slowly in the future.

Since he is a layman anyway, he can only provide ideas. For specific operations, he must still rely on the professionals in the laboratory.

Song Qi thought and walked out of the laboratory minding his own business.

As soon as he came out, his cell phone rang. Song Qi looked down and saw that it was Jiang Han. He quickly picked up the phone.

"Song Qi, where are you?"

"Just got off work, ready to go home."

"Would you like to come out for a drink? I have something to tell you!"

Jiang Han's voice sounded a little serious, different from the cheerful and jovial person he used to be.

Song Qi remembered that he hadn't told Jiang Han about Cai Xiaomei yet. It was just right to tell him today. Such a good opportunity should not be taken advantage of by others.

With this in mind, Song Qi readily agreed.

After a while, Jiang Han sent the address.

Cai Xiaomei wanted to treat Song Qi and Jiang Han to dinner that day.

Cai Xiaomei was so enthusiastic that Song Qi couldn't refuse. In addition, he and Jiang Han hadn't seen each other for a while, so they made an appointment to eat at a restaurant.

Jiang Han, who received Song Qi's call, happily called Qiao Chu and a group of friends from the emergency room.

It's been a long time since we all got together. In addition, Cai Xiaomei is also a cheerful person and doesn't have the arrogance of ordinary young ladies from rich families. It's easier for everyone to get along with each other.

As for introducing business to Jiang Han, Song Qi would naturally not talk to him on such an occasion. Cai Xiaomei also came over first to inspect the situation.

Who would have thought that Cai Xiaomei and Jiang Han would hit it off instantly, and after a few glasses of wine, they would feel like they cherished each other and regretted seeing each other so late.

Song Qi was afraid that there would be an emergency at night, so she left early after drinking two glasses of wine. When she left, Jiang Han and Cai Xiaomei were still playing guessing games and having a great time drinking!
Could it be that Cai Xiaomei told Jiang Han about that? Jiang Han disagrees? Song Qi murmured in his heart.

If you don’t agree, just don’t agree. Although the remuneration is generous, it is not acceptable to everyone. Song Qi arrived at the door of the tavern, still thinking about this matter.

Jiang Han has already arrived, ordered the food, and brought a box of beer.

"Damn it! How many people are you ordering so much beer?" Song Qi sat down and looked at Jiang Han with a serious look on his face.

"There's no one else, just the two of us." Jiang Han raised his eyes and looked at Song Qi. Said seriously.

"Are we two? Drinking so much? Let me tell you, I drink two bottles at most. My situation is different now. I have an emergency at any time at night." Song Qi quickly declared.

"Song Qi, if you are a good friend, you can drink with me today!" Jiang Han opened two bottles of beer with a beer opener, handed one to Song Qi, picked up the other, and started blowing the bottle.

Song Qi looked a little dumbfounded and quickly held down his hand, "Jiang Han, what's wrong with you? Are you terminally ill? Even if you are terminally ill, don't worry about it. Our buddy is not a doctor." After Jiang Han, Song Qi never said anything nice in front of him.

Fortunately, Jiang Han is used to it.

"Song Qi, I am not terminally ill, but I have reached the most important crossroads in my life." Jiang Han looked at Song Qi with a look of sadness on his face.

The most important crossroads in life? Did Cai Xiaomei really tell him that?

"Jiang Han, did Cai Xiaomei ask you to lend her sperm? If you don't want to, just refuse her directly. Although there is a seven-digit reward, we don't agree and she can't force it. We Although there are many things, they are only used on the blade, right?" Song Qi also took a big sip of beer and said boldly.

"Borrow sperm?" Jiang Han was confused after hearing what Song Qi said.

"Ah? She didn't tell you about this?" Song Qi was also a little surprised. He quickly told him that Cai Xiaomei wanted to use semen to give birth to a child.

"Jiang Han, I swear, I really want you to make this windfall from the bottom of my heart, but if you don't agree, just refuse and don't think about it for me. I'm not familiar with her either."

"Song Qi, she not only wants my sperm now, she also wants me as a person," Jiang Han said with a tragic look on his face.

"That night, we drank too much, and somehow we ended up sleeping together. The next morning, I originally wanted to just pretend that nothing happened, but today she called me and said she would be responsible for me."

(End of this chapter)