Doctor's Life Simulator

Chapter 253 Thrilling, new technology of liquid biopsy makes great achievements!
In the next few days, Qin Lang returned to the City No. [-] Hospital and began to create a laboratory for a new subject.

Due to the limited places for general surgery and thoracic surgery, Qin Lang is now a physician in the burn department in name, so in the end, after discussions between Dean Hang and Wei Guoqiang, in the new building of the wound treatment center, Qin Lang A laboratory was set aside.

Regarding this, the doctors in the treatment center have no objection. After all, Qin Lang's prestige in the treatment center is too high, even if he is the biggest opponent, Lu Yu has nothing to say.

After hearing the legend about Qin Lang in Zijingang No. [-] Hospital from Wang Heng, Lu Yu no longer had the slightest thought of competing with Qin Lang.

With the full support of Professor Shen, the leaders of the First Municipal Hospital also paid close attention to this laboratory. Within three days, the entire laboratory had begun to take shape. Seeing the brand-new equipment in the laboratory, Qin Lang was also full of ambition .

In the thoracic surgery department, apart from Director Zhou Heng, several physicians under him have different ideas about this brand-new topic jointly established by Professor Shen Xi, the thoracic surgery department, and the general surgery department.

For this cutting-edge theory, they feel that it is too empty.

Moreover, the development of this kind of subject requires a lot of time to invest, unlike ordinary surgical procedures, in fact, if you master it, you have mastered it.There are many uncertainties in this kind of research. Although the prospect is promising, it is more like a big pie.

For a surgical genius like Qin Lang, they felt it was a pity to waste on such scientific research projects instead of practicing surgical techniques.

The attending physician of the Thoracic Surgery Department is also Zhou Heng's proud student. Zhang Anyi's attending doctor is not very optimistic about this subject.

Moreover, in his opinion, when this kind of cross-institutional cooperation topic is actually applied to clinical practice, it will be unknown.

Only Professor Shen Xi, a mentor of this kind of scientific research, would propose this kind of topic.It is also expected in my heart that it will not take long for this kind of project to end in failure.

For so long, their thoracic surgery department has always used solid traditional techniques, combined with patients' pain signs, physicians' experienced judgments, and color ultrasound examinations, CT examinations or magnetic resonance examinations, to clearly diagnose various tumor diseases.

For the early diagnosis proposed by Professor Shen Xi, through liquid biopsy, exosome and other technologies, I am not optimistic, and I have no intention to understand and master it.

Different road non-phase plan.

Therefore, after the establishment of Qin Lang's laboratory, the doctors of the thoracic surgery department didn't pay attention to visit it, which made Qin Lang feel relieved to start the research.

Duan Bo, 60 years old this year, has retired at home. A month ago, he started to have pain in his left toe without any symptoms.

I didn't pay much attention at first, but after a few days, my toes started to turn purple, and the pain became more and more serious.Since the children in the family are busy with work, I went to the community health center to have a look.

The doctors in the health center simply prescribed painkillers, anti-inflammatory drugs, and symptomatic treatment.

A week later, Duan Bo's condition did not improve at all, but a new condition appeared, gastrointestinal problems.

Taking advantage of Saturday, the patient's son took him to the nearest town hospital. The hospital performed a color ultrasound examination on him, which indicated that the sound permeability in the dorsalis pedis artery of the left lower extremity was not good, and scattered small bright spots could be seen. Thromboangiitis obliterans was preliminarily diagnosed due to poor blood flow filling.

He was hospitalized. After the physical examination, the blood pressure was 150/100mm Hg, the heart rate was 74 beats/min, and the heart rate was uniform. No pathological murmurs were heard in the heart valve auscultation area; the abdomen was flat and soft, and no intestinal pattern and peristaltic waves were seen. , no palpable mass, no tenderness and rebound pain in the whole abdomen.

The tip of the left toe turned purple, mainly the fourth palm toe, and there were no other positive signs.Given anticoagulation, vasodilator, antihypertensive, analgesic treatment, the symptoms of foot and dorsal pain were slightly alleviated.

I thought that after a period of treatment, I would be able to be discharged from the hospital. Who would have thought that the gastrointestinal symptoms began to worsen yesterday, and symptoms such as nausea, vomiting, abdominal pain, and abdominal distension appeared at the same time.

The doctor at the town hospital directly suggested that the patient be transferred to another hospital, and was sent to the emergency department of the city's first hospital.

In the emergency department of the city's first hospital, Qin Lang and Liu Peichun happened to be on duty today.

After Liu Peichun received the patient, he learned about the past medical history and signs in detail.According to the patient's history of habitual constipation, considering incomplete intestinal obstruction, it is recommended that the patient be treated with gastrointestinal decompression and soapy water enema.

For Liu Peichun's diagnosis, Qin Lang always felt that there was something wrong, but for a while, he couldn't find the specific cause.

[Ding, new task, through the brand-new body fluid biopsy technology, find the real cause of the patient.Task reward: 1.1 life simulation points. 】

When Qin Lang saw this task, sure enough, the patient's condition was not so simple. After accepting the task, he called Liu Peichun over and put forward his own different ideas.

"Dr. Liu, I think the patient's situation is quite special. Let's not rush to give the patient gastrointestinal decompression and soapy water enema. I am going to do another set of body fluid biopsy for him. Give me two hours!"

"Body fluid biopsy technology?"

Liu Peichun didn't quite understand.

"This is recently when I was in the No. [-] Hospital of Zijingang. Following my mentor, Professor Shen Xi, I learned a new technology that can assist in the detection of some diseases. Now in the treatment center, a laboratory has been specially established. I personally treat patients. Check it out."

Qin Lang didn't explain the technical details to Liu Peichun in detail. Having experienced so many things, Liu Peichun now regards Qin Lang's advice as a standard, as long as Qin Lang is willing, he can't ask for it.

"No problem, then I will take the patient to the observation room first, and you will proceed as soon as possible."

After Liu Peichun communicated with Qin Lang, he explained the situation to the patient and his family members. Naturally, they dared not disobey the doctor's professional judgment.

Soon, Qin Lang collected body fluids from the patient.

After returning to the laboratory of the Wound Treatment Center, Qin Lang began to concentrate on testing.

Although it is still an entry-level detection technology, it is impossible to improve and understand the principles, but according to the scriptures, comparing the detection results, it is concluded that Qinlang can still be completed.

According to this entry-level detection technology, Qin Lang has a huge amount of information in his mind, corresponding to various early indicators of various tumor diseases.

For example, in breast cancer, detection of CD82 levels in blood-derived exosomes is more sensitive for early breast cancer screening and diagnosis than traditional tumor markers.

In gastric cancer, the level of serum exosomal Dicer starts to increase in the early stage of gastric adenocarcinoma and reaches a plateau after the developmental period. Serum exosomal Dicer is a potential non-invasive diagnostic biomarker that can be used for early detection of differentiation Gastric adenocarcinoma.

In melanoma, exosomal proteins PD-1 and CD28 are elevated in T cells and dendritic cells in melanoma patients.Therefore, both TEX and DEX may serve as reliable melanoma prognostic biomarkers.

Pancreatic cancer, colorectal cancer, prostate cancer, liver cancer, etc., all have their own different biomarkers.

And Qin Lang, using this brand new equipment, began to examine and analyze the patient's body fluids.

Since the patient's signs and basic physical examination have given a certain direction, Qin Lang narrowed the scope. As long as the screening is carried out according to these biomarkers, the final conclusion can naturally be obtained.

Two hours later, Qin Lang found abnormalities in three types of exosomes through bioinformatics analysis, namely: NR-3, NR-026 and NR-126.

According to the map, Qin Lang certainly found the real cause of the patient, but the result surprised him greatly.

If you follow the routine inspection, it is impossible to think that there is something wrong with the patient.

For Liu Peichun's gastrointestinal decompression and soapy water enema treatment plan, Qin Lang was also afraid for a while, but fortunately he stopped him in time, otherwise the patient would definitely not survive tonight.

At the first moment, Qin Lang called Director Zhou Heng of the Thoracic Surgery Department.

(End of this chapter)