Chapter 362
Handing the draft paper to Perelman, seeing that Perelman didn't react, Qin Yuanqing smiled triumphantly and strode away from the Institute for Advanced Study.

Then it will be handed over to Perelman. Qin Yuanqing estimated that with Perelman's ability, he should be able to unlock it in about a year.

Qin Yuanqing went to the Shahe campus. It was already the end of April. The construction of the entire Shahe campus lasted for more than a year. The automobile research institute and the aviation engine research institute are basically about to be renovated. In about a month, the two research institutes can officially move into the new place.

It can be said that until now, except for the decoration, communication, communication, electricity, water, etc. have all been completed, and there are still more than 4000 workers in the Shahe campus every day.

The speed of the construction of the entire Shahe Campus is a miracle. Normally speaking, it is normal to build for four to five years. However, under the influence of a large amount of manpower, material and financial resources, the "Pengcheng speed" was displayed.

Of course, this is also related to the lack of high-rise buildings in the Shahe campus. Without high-rise buildings, the foundation treatment is not so troublesome.

Seeing the Shahe Campus being built from scratch, bit by bit, Qin Yuanqing was filled with pride and pride. After all, he also put a lot of effort into the construction of the Shahe Campus.

"According to this progress, it should be no problem to complete the construction before the Spring Festival this year!" Qin Yuanqing guessed in his heart. According to the plan, the aero-engine research institute and the automobile research institute will be completed next month, and they will move in in August.Then other departments will gradually move into the Shahe campus. Around the Spring Festival, the relocation of scientific research institutions and major departments will be basically completed.

Entering the laboratory, Qin Yuanqing was pleasantly surprised by the result. This is a paper, which introduces the discovery of some bacterial mutations in a lump of mixed substances during the experiment.

"Is it accidental, or inevitable?" Qin Yuanqing looked thoughtful after reading the paper, but Qin Yuanqing felt that it was necessary to check it out. Of course, Qin Yuanqing still agreed to let the paper be published. There are some meanings, worth exploring.

Qin Yuanqing arrived at the laboratory, and then looked at a pile of mixed substances, which were left over from the experiment.

This kind of mixed substance cannot be handled casually. Although this is only the researcher's own hobby, the study of norovirus is not among the subjects listed in the laboratory, but the laboratory does not prohibit researchers from studying their own hobbies, as long as it does not affect laboratory topics.

This paper is a researcher who discovered a strange phenomenon in this mixed substance when he was studying Norwalk virus, and then wrote such a paper. Level periodicals are more than enough.

Norwalk virus, also known as Norovirus, is the prototype representative strain of the Norovirus genus in the family Caliciviridae.It is a group of virus particles with similar morphology and slightly different antigenicity.Norovirus infectious diarrhea is prevalent all over the world, and infection can occur throughout the year. The infected objects are mainly adults and school-age children, and the incidence is high in cold seasons.Norovirus is responsible for 60-90% of all outbreaks of abacterial diarrhea in the United States.Among Chinese children with diarrhea under the age of 5, the detection rate of norovirus is about 15%. The survey of serum antibody levels shows that norovirus infection is also very common in the Chinese population.

"Norovirus" infectious diarrhea is a self-limiting disease, and there is no vaccine or specific drug. At present, people's understanding of it is still relatively limited.

"Director!" A young doctor greeted Qin Yuanqing quickly.

"Pang Bo, I read your paper, and this discovery is very interesting." Qin Yuanqing said.

That thesis was written by this Pang Bo. Pang Bo graduated from the Department of Medicine of Yanda University with a bachelor's and a master's degree. Later, he went to study in the United States. After graduating from a Ph.D., he worked in a doctoral station for 3 years. When Qin Yuanqing was recruiting, Pang Bo sent his resume ,Selected.

Pangbo was studying norovirus in the United States.

Qin Yuanqing looked at the pile of miscellaneous substances, which were regularly cleaned and specially disposed of every day.After all, although the harm of norovirus is not high, once it is infected, it will be difficult to tell.

In that huge pile of experimental waste, the cell material is almost dead. It must contain a large number of noroviruses, and a lot of bacteria have grown. There may be a war between bacteria and viruses, and I don’t know the new bacteria. Can be infected by norovirus.

Qin Yuanqing showed a thoughtful look, thinking about the phenomenon introduced in the paper.There are still surviving protocells in the mixed substance, and the number of them is very small. Most of the protocells are not infected and died by norovirus, but are still breeding in the surroundings under an unsuitable chemical environment and without suitable material supply. A large number of bacteria occupy the living space and cause cell death.Furthermore, some noroviruses have mutated, which is invisible to the naked eye, and there are uncertainties.

On a blackboard in the laboratory, Qin Yuanqing began to write symbols, numbers and graphics with chalk.

"Pangbo, do the experiment as I told you, let's do a dyeing experiment!" Qin Yuanqing stopped writing and said to Pangbo.

"Okay, Director!" Pang Bo's eyes flashed with joy. He didn't expect his research to arouse Qin Yuanqing's interest.

These researchers all know that Qin Yuanqing has extremely terrifying attainments in theory, which is bottomless.Therefore, there is a popular saying among their researchers that if you encounter any difficulties and cannot overcome them, the easiest way is to make it arouse Academician Qin's interest. As long as Academician Qin is interested, then solving it will be a matter of course .

Under Qin Yuanqing's command, Pang Bo prepared some virus materials, and then began to divide ten groups into dyeing experiments according to Qin Yuanqing's request. He also added a new virus and did the same dyeing experiment in two groups.

Staining experiments are mainly to observe chromosomes.

Unlike in the past when the glassware was disposed of after the experiment was over, this time Qin Yuanqing asked to just put it there, keep it, observe it every day, and record the corresponding data.Do the same experiment again at the same time, and repeat it over and over again.

The daily data is recorded in a computer form.

Finally, after ten days of experimentation, the extraction began. Of course, instead of extracting samples, a large number of viruses were isolated from them.

With the end of the experiment, Qin Yuanqing was finally sure that the virus had mutated.In the environment of the staining experiment, the cells themselves will be affected by the harsh environment. If there is no intervention, more cells will die due to the harsh environment than those infected by the virus.This also affects the living space of the virus. Without cells to invade, the virus cannot reproduce.The reason is that the next generation cannot be reproduced. Under special circumstances, the virus mutates, becoming more infectious and less virulent.

It can be said that through this month, the characteristics, infection mechanism, and mutation direction of norovirus have been thoroughly explored, so it is a matter of course for the proposed vaccine and specific medicine based on this.

"Pang Bo, Yan Ning, the experiment has verified my idea, and the paper will be handed over to you next." Qin Yuanqing said with a faint smile.

During this month, Qin Yuanqing theoretically established a mechanism model that fully reflected the norovirus infection and mutation pathways, and then listed its calculation formula, as well as the proposed vaccine and specific medicine.

Although norovirus is very common, highly infectious, and of great significance, in fact, this achievement is not as good as the previous myocarditis. After all, myocarditis is a study of heart disease, and its breakthrough represents the human progress in the field of heart disease. Taking an extraordinary step is an achievement at the level of the Nobel Prize in Physiology, so the country decisively awarded the first prize of the National Natural Science Award to Qin Yuanqing and Yan Ning.

In contrast, norovirus is much worse. After all, norovirus is not very toxic, and this virus infection can be prevented by strengthening drinking water sanitation, improving food hygiene, and improving personal hygiene.And even if it is infected, the fatality rate is very low.

Of course, there is no problem with the birth of [-] or [-] papers on the results of norovirus this time, and each paper is enough for a higher-level journal.

Moreover, in comparison, the application value of vaccines will be very wide. Everyone needs to be vaccinated, so the economic benefits of this achievement are also very prominent.

"Director, don't worry, the paper will be handed over to me and Director Yan!" Pang Bo said excitedly.

During this month, he spent most of his time in the laboratory, and went home to sleep every day, but now he is entering the harvest stage.

According to Qin Yuanqing's personality, he can't get away with one paper and one work.With this achievement, it was only a matter of course for him to select a professor or a first-level researcher.

More importantly, norovirus is Pangbo's hobby. Now that norovirus has made a breakthrough, it can benefit the whole human being. The sense of accomplishment in Pangbo's heart is far beyond what he can get with money.

At the beginning, he chose to study medicine because his younger brother was infected with norovirus. As a result, because his parents had poor medical knowledge in the countryside, his young brother died of dehydration.And after filling out the volunteers after the college entrance examination, Pang Bo did not hesitate to choose the Department of Medicine of Yanda University, and he did his undergraduate and master's studies.After graduating from graduate school, he felt that his understanding of norovirus was still very shallow. He chose to study abroad to study this area of ​​research, and the postdoctoral workstation was also engaged in this area of ​​research.

After returning to China and joining Qin Yuanqing's laboratory, Pangbo will continue to study noroviruses in his spare time because he has a wish in his heart to solve noroviruses so that human beings will never suffer from noroviruses.He can also go to his younger brother's grave, burn incense for his younger brother, and then tell his younger brother that he has finally solved the norovirus.

(End of this chapter)

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