I can see health

Chapter 325 Research Changing Clinical Guidelines?
"Lu Chen, there is a male patient who needs to be catheterized, please come and help me, it's on bed 10."

Gong Nannan walked into the doctor's office and said to Lu Chen with a smile.

"Okay, I'll be here soon."

Lu Chen was writing his medical history. Hearing what nurse Gong Nannan said, he stood up and walked out of the office.

Ever since Lu Chen came to the emergency department, many male patients have been entrusted to him for the catheterization.

Therefore, urinary catheterization became one of the skills that Lu Chen could reach 100% proficiency the fastest.

Bed 10 is a young man in his 20s.

"Don't be nervous, it will be fine soon." Lu Chen came to the bedside of bed 10.

The young man looked green and embarrassed, and whispered, "Oh, take it easy."

"Don't worry, take off your pants first." Lu Chen put the catheterization bag on the operating table beside the bed.

"Ah? This..." The young man blushed.

"What are you afraid of, you are all old men." Lu Chen said seriously, "It will be over soon."

"Oh." The young man took off his pants hesitantly.

After about 1 minutes.

"Okay." Lu Chen smiled and said to the young man in front of him, "There is nothing uncomfortable."

The young man nodded: "Thank you."

Lu Chen packed up the rest of the medical waste and threw it into the yellow medical waste bin.

"Congratulations, received the thank you from Ma Ping +1!"

Inserted a urinary catheter, got a little thank you.

Lu Chen left the emergency ward contentedly.

……

"Hey, Lu Chen, I heard that our opening time for this year's topic has been advanced."

As soon as he returned to the doctor's office, Cheng Peng came over.

"When is it early?" Lu Chen was taken aback.

He has been busy doing clinical research data recently, so he really didn't notice these things.

The opening of the topic involves the direction of the topic and determines the research direction of the entire three-year postgraduate study.

"Probably after New Year's Day." Cheng Peng thought for a while.

"After New Year's Day?" Lu Chen frowned.

The electrocardiogram national competition is almost during the new year's day.

That is to say, after he finished the competition and returned to school, he would almost start the question opening.

"Isn't it because a certain star has an accident, and he has a Ph.D. He doesn't even know what it is." Cheng Peng curled his lips, "Now the Ministry of Education has stricter censorship of papers. In the past, the repetition rate was no more than 20%. In our current class, it’s actually less than 10%, it’s too perverted! So in order to let us prepare the thesis earlier, the school has advanced the time for opening the topic.”

Lu Chen had also heard about this celebrity.

However, the quality of Huaxia's dissertations is indeed poor now. Many of them are just one article, or they can graduate after translating foreign languages.

"Time is running short." Lu Chen thought to himself.

The usual opening time is the start time of the second semester, but this year it has been directly advanced to the first semester.

Lu Chen has some ideas about his own clinical projects, but he still needs early data support.

He is now doing research on this early data.

If even the previous data are meaningless, then there is no need for him to continue.

The most important thing now is that before New Year's Day, the data of this early stage should be produced quickly.

……

Eight districts in the heart.

Office of the Director.

Lu Chen, Ke Yue and Jiang Qingyan stood in front of the desk.

Li Yao looked down at the opening report of the three of them.

The corners of the mouth are sometimes raised, and the brows are sometimes wrinkled,
half an hour.

Li Yao said slowly: "Well, Jiang Qingyan's idea is good. The toxic effect of anti-tumor drugs on cardiovascular is a very interesting research direction. The research in this field abroad is very mature, but it is still in its infancy in China. .”

"However, Ke Yue, this opening report of yours..." Li Yao looked up at Ke Yue, "How should I put it, it seems that there is no problem in studying the relationship between platelet aggregation and cardiovascular disease, but, have you checked it out? Someone else's research literature?"

Ke Yue lowered her head, "Look, I've seen..."

"Then you should also know that there are already many mature research and development results in your research field. If you do it again, although there is no fatal problem in the whole research topic, it is difficult to make something more innovative. In a word, it is like a chicken rib , it’s tasteless to eat, and it’s a pity to throw it away.”

"Yeah." Ke Yue's voice was weak, "Teacher, I'll look for the literature when I go back."

Li Yao nodded and said nothing more.

Only Lu Chen's opening report was left, and Li Yao didn't express any opinions.

In the office, it was a little quiet.

Li Yao tapped the table with the index finger of her right hand, making a small but regular sound.

After a while, Li Yao looked up at Lu Chen.

"Regarding the research on the prevention of early heart failure in patients with acute myocardial infarction with dapagliflozin, is this research topic your own idea?"

Ke Yue and Jiang Qingyan looked at Lu Chen who was on the side.

Is there any problem with this subject?

Lu Chen nodded slightly.

In fact, with the help of the system, he applied the clinical scientific research skills card, combined with the current popular research field of cardiovascular medicine.

Finally, it was hard to think of this research topic.

"Very good, very good!" Li Yao said twice in a row, "Dapagliflozin is a relatively hot drug at present, and major laboratories around the world are researching it, and the research and development direction you chose is currently at home and abroad. It should be blank! If you can do it well and publish a high-scoring SCI, there is no problem."

"Even, if the sample size of the study is large, a large-sample, multi-center clinical study will be conducted, and the final research and development conclusions will even be able to change the clinical treatment guidelines!"

Changes to clinical guidelines?

Everyone present, including Lu Chen, all showed expressions of astonishment.

Lu Chen originally just wanted to publish an SCI paper, but he didn't expect Li Yao to give such a high evaluation.

Ke Yue and Jiang Qingyan looked at Lu Chen in disbelief.

No one would have imagined that the opening report made by a graduate student might change the clinical guidelines!
Li Yao continued: "Don't be so surprised, you need to know. Dapagliflozin has just been listed as a routine drug for the treatment of heart failure, and its status has been recognized in the medical field, but it is not clinically effective in acute Research on myocardial infarction, so it has not been included in it."

"but……"

Li Yao changed the subject and stared at Lu Chen closely: "Everyone knows that clinical research is not a method! It requires a lot of manpower, material resources and financial resources! The sample size you wrote in the opening report is only 50. People, with this kind of sample size, at most one low-scoring SCI paper will be published. If you want to change the clinical guidelines, then the number of such papers should be at least tens of thousands! Generally, this kind of research to change the clinical guidelines is led by the leading hospitals in the country Major tertiary hospitals have a large sample size, so the results of such a study are applicable to clinical practice."

Lu Chen nodded, he understood what Li Yao meant.

In clinical scientific research, good ideas are important, but they require a lot of financial and material resources.

In prospective research, only a sample of 50 people is definitely not enough, it can even be said to be very, very few!
But with a sample size of 50 people, tens of thousands of funds need to be spent, or even more.

This is also the limit that Lu Chen can bear at present.

It is not realistic for Lu Chen to spend more money on clinical research!

"How about it." Li Yao continued, "Lu Chen, you should make a sample size of 50 people first. If the experimental research in the early stage is meaningful, then consider whether there is any further possibility."

"Good teacher." Lu Chen smiled.

"Actually, the sample size of 50 people cost a lot of money." Li Yao said in a deep voice, "I will give you a partial subsidy in the name of the laboratory. Secondly, when you collect data, I will let you The medical staff in District [-] will cooperate with you."

The so-called prospective research requires patients to return to the hospital for reexamination in time, which involves examination fees, round-trip travel expenses, and so on.

"Thank you teacher!" Lu Chen looked delighted.

The biggest obstacle for him now is not the funds, but the cooperation of the medical staff and nurses in the clinical experiment if he wants to do a good job in the clinical experiment, otherwise it will be difficult to collect first-hand data.

Now with Li Yao's Shangfang sword, Lu Chen's future clinical research should be much easier.

"By the way, so are you two." Li Yao said to Ke Yue and Jiang Qingyan, "I will let the nurses in the department cooperate with you."

"Thank you teacher." Ke Yue and Jiang Qingyan said in unison.

When they walked out of the director's office, the three of Lu Chen had happy expressions on their faces.

As a mentor, Li Yao is quite responsible for being able to do this.

Many graduate tutors basically let students fend for themselves.

Some tutors even impose unreliable research on students.

……

Seeing the backs of the three leaving the office, Li Yao was very relieved.

The quality of students this year is too high.

The clinical research topics of Lu Chen and Jiang Qingyan are very innovative, and they should be able to produce good results.

Ke Yu's subject was a bit poor, but he was qualified enough to graduate.

For the students of the previous two classes, Li Yao did not give such convenient conditions.

It can be seen from the body of Senior Sister Wang Shasha.

"I hope the three of them won't let me down."

Li Yao looked at the three opening reports in front of her with a smile on her lips.

……

Leaving the doctor's office, the three of Lu Chen walked along the path of the hospital.

"Lu Chen, you are really good. The teacher said that your subject can even change the clinical guidelines!" Ke Yue couldn't help giving Lu Chen a thumbs up.

"That's a large sample size. I only have [-] samples right now, and it's enough to send an SCI." Lu Chen smiled.

This is not his modesty, this is determined by the sample size.

"Oh, it's already very powerful!" Ke Yue laughed.

At the same time, she was also happy.

It seems that helping Lu Chen record data is a very correct choice!
If Lu Chen can post an SCI with her name on it, he will make a lot of money.

"Jiang Qingyan's topic is also good." Lu Chen smiled, "Ke Yue, you have to revise your opening report."

Jiang Qingyan smiled.

Ke Yue pouted, "Hey, I see, it seems that I have to stay up late again..."

The three chatted all the way and parted in front of Gui Peikou's dormitory.

……

Back in the dormitory, everyone in the dormitory was discussing the opening of the topic.

"The data in the early stage of my project is almost done." Wang Zihao patted Lu Chen on the shoulder, "I still have to thank Lu Chen! Without you, I would not be so fast."

"Hey, I don't even have any ideas, and I'm about to open a question. It's really difficult!"

Another roommate, Xing Yu, frowned bitterly.

"Brother Yu, go and ask your boss! Doesn't he have any subjects?" Wang Zihao asked suspiciously, "Just asking you to do a sub-project should be enough for you to graduate, right?"

"Hey, I asked." Xing Yu smiled wryly, "My boss asked me to think about it myself, and then let him change it after thinking about it. As for his subject, I think he can't figure it out by himself, and he is looking for an outsourced experiment. If I want him to give me a sub-project, don't even think about it."

"Um... It's really difficult for you to meet an unreliable boss." Wang Zihao shook his head slightly, and then looked at Lu Chen who was beside him, "Lu Chen, have you finished your clinical project?"

"The opening report has been written, but the preliminary data has not been completed yet." Lu Chen shook his head.

"Then hurry up." Wang Zihao said, "I remember you are going to Ice City to participate in the electrocardiogram competition, right? When you come back from Ice City, we will almost have to start the topic."

"Yeah." Lu Chen nodded, "I asked two classmates to help, and I should be able to complete the preliminary data."

"That's good." Wang Zihao said.

Everyone in the dormitory chatted for a while.

Wang Zihao suddenly received a WeChat message, and after reading it, he said, "Lu Chen, my sister wants to treat you to dinner again."

Lu Chen was processing the data of clinical scientific research, and was taken aback when he heard this.

"Didn't you already eat it some time ago? Why did you eat it again?"

"The last time was a thank-you banquet. This time she is going to come to the hospital for a follow-up visit." Wang Zihao said, "So I want to make an appointment with you in advance to know something about you."

"It...isn't necessary." Lu Chen said, "When your sister comes for a follow-up visit, just ask her to go to the outpatient department of cardiology. I can't prescribe medicine, and I can't do any examinations."

"I told her this, but she still wants to come to you." Wang Zihao said, "Lu Chen, you should just go and have a free massage, anyway, it's only one morning. So my sister won't bother me again."

Lu Chen thought for a while and said, "When?"

"Tomorrow is the weekend, let's do it tomorrow, at 11:30 noon, at the Shangri-La Hotel."

"Shangri-La... Isn't it cheap?" Lu Chen smiled.

"Don't worry, my sister is a rich woman." Wang Zihao smiled, "If you eat a few more meals, you won't be able to eat her poor."

At this time, Xing Yu whispered from the side: "Zihao, I also want to rub it, I don't want to work hard..."

"Get out, go away." Wang Zihao scolded with a smile, then looked at Lu Chen, "How are you going?"

Lu Chen nodded: "You've said that, I'm definitely going. But, can you change the place? The restaurant in front of our hospital is delicious and affordable. I have to process data tomorrow afternoon. Besides , Going to a high-end western restaurant like Shangri-La is too restrained, and my appetite is not much better."

"It shouldn't be a problem. I'll contact my sister." Wang Zihao said with a smile.

……

(End of this chapter)