godfather of surgery
Chapter 1054 Tenacious vitality
Chapter 1054 Tenacious vitality
In fact, Zhang Chunquan from the American Whitehead Laboratory had visited Nandu Medical University before visiting Peking Union Medical College. He asked to meet Yang Ping, but was rejected by Yang Ping. Whether from an emotional or profit perspective, Yang Ping thought it was unnecessary to meet him and it was a waste of time.
To be honest, the purpose of cooperation is to learn from each other's strengths and achieve a win-win situation. To put it bluntly, it is to take advantage of each other and take what each needs. Yang Ping is now the world's number one in the field of stem cell research. He is one dimension ahead of other research teams, so he does not need to cooperate with other laboratories now. These so-called cooperation and sharing will only benefit others.
When Yang Ping's stem cell research had not yet started, even Chinese people were refused visits to Zhang Chunquan's laboratory on the grounds of preventing the leakage of cutting-edge technology. Now they have proposed that science has no borders and that we should work together to contribute to the advancement of human medicine. This is not a joke. They are always right. They speak so high-soundingly, but in fact it is all for their own interests.
When they have an advantage, they talk to you about intellectual property and confidentiality; when they are at a disadvantage, they talk to you about science without borders and cooperation.
Yang Ping wouldn't buy it. In his eyes, cooperation was a naked exchange. If there was nothing of equal value to exchange, there was no point in discussing it.
"Xiao Yang!"
Yang Ping had just returned from Nandu Medical University and received a call from Professor Liang.
"Professor Liang!" Yang Ping hadn't contacted Professor Liang for some time.
Professor Liang was in a good mood these days. He knew about this matter. Song Yun had told him about it. Professor Liang had already given up on Zhang Chunquan's matter, and the knot in his heart had long been untied.
However, Zhang Chunquan did provide some help to some laboratories when he returned to China. This made Professor Liang very happy, thinking that he had misunderstood Zhang Chunquan. He originally refused to meet Zhang Chunquan, but finally agreed to meet him. The master and apprentice reunited, and Professor Liang was very excited.
When Zhang Chunquan proposed that he needed Professor Liang to act as a go-between for the cooperation with Yang Ping, Professor Liang finally understood that his previous cooperation with other universities was just a prelude. In the end, he still wanted to cooperate with Yang Ping, but was rejected by Yang Ping. So the cooperation with Yang Ping was in trouble. He wanted to use the relationship between Professor Liang and Yang Ping to make a breakthrough. The so-called visit to his mentor was just for the sake of his mentor's value.
For more than ten years, not to mention visiting his mentor, he didn't even write a letter to him. Now he suddenly visits his mentor with great fanfare. How painful Professor Liang's heart must be at this moment.
Yang Ping had known about Zhang Chunquan's return to China. He had sent people to contact Yang Ping before, but was rejected by Yang Ping. He himself tried to contact Yang Ping several times, but was also rejected by Yang Ping. Later, because Yang Ping was busy with other things, he didn't pay much attention to him. Unexpectedly, he ran to Professor Liang.
Professor Liang was silent for a moment on the phone: "Xiao Yang, Zhang Chunquan didn't come to find you, right? You must stay sober at this time. Whether it's him or someone else, there will be many temptations thrown at you now, you must stay calm."
"I understand. Thank you Professor Liang for the reminder. He has looked for me, but I haven't met him. I don't want to see him..." Yang Ping explained clearly on the phone why he didn't want to see Zhang Chunquan, so as to prevent the old man from worrying about him.
After hearing this, Professor Liang felt relieved. He no longer worried that Yang Ping would be tempted and make some stupid decisions. Yang Ping's maturity in this regard exceeded Professor Liang's imagination.
Yang Ping reported some of his recent research to Professor Liang, who was stunned. He didn't expect that after a while of no contact, Yang Ping would run a long way. He actually achieved great results in the treatment of osteosarcoma. The method he used was brand new, and he had never heard of it before. K factor, carrier virus, and tumor cell apoptosis program were all world-class. Zhang Chunquan could not compare to this level. It seems that our real top talents are still serving the motherland and have not been lost.
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As for Zhang Chunquan's visit, if Professor Liang hadn't mentioned it, Yang Ping would not have the time to pay attention to it. Yang Ping is not worried that Professor Liang will be sad about this matter, because Professor Liang has already fallen ill because of Zhang Chunquan, and now he should have seen through everything and will no longer have any emotional fluctuations.
These days, Yang Ping goes to Ruixing Company and Nandu Medical University every other day. Professor He's team has developed a biomedical image recognition engine. This engine does not need big data to feed it. It operates based on digital humans and uses normal cells in digital humans as a reference. It has many modules. The module currently developed is the recognition of cell images under electron microscopes. It can automatically compare each image with normal cells of the same type. Images with differences will be retained for the next step of recognition, so that the requirements of experimental views can be met step by step.
Yang Ping handed the remaining electron microscope images to the intelligent engine for viewing. It was very fast and took only a few minutes to read all the images. It successfully found three images. These three cell images had the structure of K virus, indicating that they had successfully infected the tumor cells.
The experimental team is still continuing to observe Sisi's dynamics. They puncture her metastatic tumors and obtain living cells almost every few days. In the second batch of electron microscope images of living cells obtained by puncture, they finally found a picture of tumor cells in a state of apoptosis. Although there is only this one picture, it is a question of existence or non-existence, a question of 0 to 1. Now it can be basically confirmed that the K virus can not only infect Sisi's tumor cells, but also initiate the apoptosis program of tumor cells.
After confirming these two points, Yang Ping became more confident in this experiment, which showed that the general direction of this experiment was correct.
According to Yang Ping's philosophy: do things right first, then do things well. Now it seems that things have been done right, and the next task is to do things well.
Based on the results, Yang Ping speculated that after the K virus passed through the human immune system, the number of viruses that reached the tumor was already very small. The main task now is to improve the structure of the virus so that they can successfully pass the immune system, and they must continue to maintain the ability to infect tumor cells and initiate tumor cell apoptosis. The latter is the most important. Without the latter, even if the virus can evade the human immune system in large numbers, it will be of no avail.
There is still a lot of work to be done, such as improving the detection method. Currently, we rely on puncture to obtain tumor cells and observe them under an electron microscope. However, this method cannot be used during actual treatment. This method is only suitable for initial experiments. Therefore, we need to develop supporting detection methods in the future. We can use blood draws to detect the number of virus-infected tumors and the number of tumor cell deaths. This is an arduous task and we will do it slowly in the future.
Yang Ping's current thinking about scientific research is also correct - to make full use of computers, not simply to use computers to assist in scientific research, but to use artificial intelligence technology as a basis to develop various auxiliary tools to maximize the role of computer assistance, not only to free manpower from heavy work, but also to improve work efficiency thousands of times.
For example, if we rely on manpower to identify images under an electron microscope, it will take a long time even if everyone works day and night. However, with the help of a computer, we can read all the images in a few minutes. Although the accuracy will not be ideal at the beginning, it will become more and more accurate as the model is improved. In fact, Yang Ping now thinks that the system strike is not a bad thing, but a good thing. When there was a system to help, Yang Ping would definitely not rush to develop these computer-aided tools, such as artificial intelligence and image viewing engines. After all, the demand is not very large, and the sense of urgency is not very strong.
Now that Yang Ping has lost his system, he is eager to create a new "system". This system is computer tools. Although these tools are very crude now, they will be very useful intelligent tools in the future. These tools can not only be used by Yang Ping, but also by others, and can contribute to the entire scientific research community.
Now Yang Ping wants to move scientific research from the "manual work era" to the "industrial era", and the value of these computer tools is undoubtedly equivalent to the "steam engine".
In order to cooperate with Yang Ping's experiment, Director He's team had to develop various computer tools. In fact, these scientific researchers in the laboratory have very good brains. Many of them are passionate and curious about new things, so they like to study these new things. However, because corporate researchers have commercial tasks, it is difficult for them to come up with new things that are not related to commercial tasks.
The classic programming language C and operating system UNIX were developed at Bell Labs and are still widely used today.
Ruixing Group has also established an artificial intelligence research institute and a specialized artificial intelligence technology company. This company and institute will then cooperate with Professor He's team. In this way, the strength of the entire large team will be enhanced, and the development of these tools will be a piece of cake.
Huang Jiacai spent a lot of money to recruit a group of top talents in artificial intelligence, integrated some acquired technologies with Professor He's digital human, and developed artificial intelligence models.
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Sisi gradually recovered from the first experiment. In fact, the situation was still quite dangerous at that time. The high fever of 42 degrees lasted for such a long time, and no antipyretic medicine was ineffective. The heart rate was so fast that the whole body could collapse at any time from the high fever.
Everyone was very anxious at the time, and Yang Ping kept telling himself that he must remain calm and rational, so he behaved extremely calmly throughout the whole process to ensure that he did not make mistakes. In that situation, a small misjudgment would result in irreparable serious consequences.
In the ward, Yang Ping saw Sisi fiddling with her cactus again. She looked much better than in the previous few days. However, after escaping death, it was still possible to see that the high fever caused by the virus had left marks on her body. Her lips were cracked, her complexion was very bad, and she looked very weak.
"Professor Yang, do you think this cactus is amazing? There was a time when it looked like it was about to die, and all the exposed parts were eaten by insects. I thought it was going to die, but then I changed the soil for the remaining cactus and paid attention to killing insects. It slowly came back to life and is growing very well now. So I admire it very much and always put it in my room. I feel that I will be able to survive like it." Sisi said to the cactus.
No wonder the little girl always brought her cactus with her every time she was hospitalized. Here is another such story, and it is a very positive story.
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"Don't you think so?" Sisi asked Yang Ping.
Yang Ping looked at the pot of cactus. Now it is hard to see the tragic state it was in then, but the vitality of the cactus is indeed very strong. It can be said to be the plant with the strongest vitality. It is not afraid of severe cold or drought. Just cut a piece of cactus and stick it in the soil and it will survive. Even in the desert it can still live well, releasing its green color to the fullest.
"Of course, so we don't have to worry at all. Although the process is tortuous, the future is definitely bright."
Yang Ping opened the painting in his hand and showed it to Sisi: "The data collected in the first experiment is very optimistic. Although we only found a few meaningful pictures, it is these few pictures that prove that the assassin K virus we sent out can successfully approach the enemy and kill it. However, most of the assassins we sent out this time were eliminated by the guards in your body, and only a few succeeded in infiltrating."
"What should we do then?" Sisi widened her eyes.
"We need to modify the K virus again. The previous K virus and the source virus have very different effects on the immune system. It's like a brand new virus. We now need to modify it to be as close to the source virus as possible. This closeness refers to the interaction with your immune system." Yang Ping pointed to the drawing he had drawn and started a discussion with Sisi. He treated Sisi like a student.
Although some of Sisi's ideas are sometimes naive, Yang Ping will discuss them with him seriously, just like discussing issues with the world's top scholars.
"Wait a moment, I'm going to wash my hands." Sisi looked very serious. He decided to have a good discussion with Yang Ping after washing his hands.
After washing her hands, Sisi spread out the blueprint on the table beside the bed: "Is it because the previous assassins were not well disguised and were discovered by the guards? Now I have to help them disguise themselves again so that they can deceive the guards in my body?"
"That's it. Not only do we have to disguise the assassin, but we also have to ensure that his ability to carry out the assassination is not weakened. We have to take both into account and not lose sight of one while focusing on the other." Yang Ping explained in a language that she could understand.
"I understand. When will the next experiment be done?" Sisi was looking forward to it and she didn't seem afraid at all.
Yang Ping was stunned for a moment: "Don't be impatient, you just finished your first experiment, you must recover, otherwise it will be difficult to withstand the impact of the second experiment. We must prepare for the worst in each experiment and can't take it lightly."
"It's nothing, just a high fever. I was in a daze and didn't know anything. When I woke up, I saw many faces surrounding me." Sisi still remembers the high fever she had during her first experiment, but she is not afraid.
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