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Chapter 669 It's Not the Same Thing (Update September 9, 5)
Myocardial ischemic infarction, the heart muscle cells are completely dead.Cardiomyocytes and nerve cells in adults are a class of cells with extremely poor regenerative capacity.Therefore, myocardial infarction caused by myocardial ischemia and brain nerve death caused by stroke are almost irreversible damage.In clinical practice, the treatment of these two diseases also pursues speed most - the faster the myocardial infarction and cerebral infarction are reversed, the easier it is to control the extent of damage.The smaller the extent of damage, the easier it is for the patient to recover later, and there are fewer sequelae.

It is precisely because these two injuries cannot be reversed clinically, so in the treatment, once doctors determine that these two areas may be at risk, they will actively intervene.

With the development of modern medicine, the fatality rate of acute pancreatitis has been so low that it can not be taken seriously.However, cerebral infarction and myocardial infarction are still the No.1 and No.2 causes of death among Chinese residents.

If the regeneration of cardiomyocytes and nerve cells can be solved, there may be solutions to many incurable diseases.Perhaps one day, those patients suffering from diseases will be able to regain a healthy heart and a normal brain with the help of a single dose of medicine.

But this kind of thing, today's doctors can't do it.Therefore, we must do everything possible to avoid myocardial infarction or cerebral infarction in patients.

Hypokalemia is a very dangerous symptom, which can induce various muscle paralysis, and even lead to more serious arrhythmias and even cardiac arrest.However, hypokalemia caused by plasma exchange can be completely prevented-as long as blood potassium is monitored more closely and potassium supplements are ready at any time.

The treatment plan was carried out by a specialist doctor, and Sun Lien sat in his office, flipping through various literatures.He was still a little uneasy deep in his heart——Wang Ge's blood lipids rose too fast, too much.In the past, although I have heard that some patients will have symptoms of increased blood lipids after receiving hormone shock, Sun Lien has not encountered such a situation.What made him even more puzzled was why it rose so fast.

The hormone shock is not without risks.Before undergoing hormone shock therapy, family members need to sign a notification letter, which lists the possible risks of various hormone shocks.

However, the work of consulting relevant literature was not very smooth. After the recent revision of CNKI, Sun Lien often encountered the problem that good literature could not be downloaded.The information on Wanfang is not complete enough, and the papers on PUBMED have some relevant content, but they are all paid articles-a Japanese paper from around 2000, and the journal website is priced at $39.96.

While doctors are more than willing to share their experiences with each other, it's clear that capitalist journal publishers don't think so. The thesis 20 years ago cost close to 300 yuan to download, and the thesis itself was only a four-page PDF plus six pictures.This is no longer a matter of robbing... This is simply a knowledge monopoly.Compared with this kind of fee, how much is three or five yuan for a paper on HowNet, which is as cute as a little white rabbit and harmless to humans and animals.

Although the heart is full of dissatisfaction, the health of the patient is still very important.Sun Li'en gritted his teeth and stomped his feet, and successfully spent the first payment in his life to a foreign journal.Then I downloaded this Japanese paper from 2000.

This is a case study and discussion of hyperlipidemia in patients after renal transplantation.The author recorded in detail 129 patients with hyperlipidemia after kidney transplantation.It is also proposed that after patients treated with methylprednisolone were switched to tacrolimus, the original hyperlipidemia was significantly improved.

After reading the paper, Sun Lien was a little disappointed.The content of this paper is very rigorous, and the arguments are very detailed.But I don’t know if it’s because the Japanese prefer a low-fat diet. The triglycerides of the most severe hyperlipidemia patients recorded in the paper are only 282mg/dl, which is about 31.83mmol/L.This is still a long way from Wang Ge's blood lipid level of 50mmol/L.

Although the triglyceride level of Japanese patients did not rise as fast as Wang Ge, when receiving 500mg/D methylprednisolone treatment, the probability of hyperlipidemia in patients is still very high.Of the 947 patients recorded in the paper, 129 had elevated triglycerides to varying degrees.Almost 13% of the incidence of hyperlipidemia, it seems that there is no problem.

"What are you doing?" Yuan Pingan wandered to Sun Lien's side, stretched his neck to glance at the computer screen, and then asked in surprise, "Check the literature?"

"I'm a little worried about Wang Ge's blood lipid level." Sun Li'en sighed, "It's only the second day after the hormone shock, and his triglycerides have reached 50..."

"Is there... is there anything to worry about?" Yuan Ping'an asked a little puzzled after pondering for a while, "Is it a normal side effect to increase blood lipids after receiving hormone shock therapy?"

"Yes." Sun Li'en nodded, "but from normal to 50 suddenly, this level is too high. I'm worried whether there are other factors that cause such a high triglyceride level, so check the literature to see .”

Yuan Pingan frowned and thought for a while, then continued to shake his head, "I really don't think there is anything special about this situation - I have seen more exaggerated increases in the Tongxie before. After receiving the hormone shock treatment, this It's all normal..." He shook his head and continued to ask, "Forget it, it doesn't matter what I think, have you found any relevant content?"

"No." Sun Li'en sighed, "I've never seen such a high increase, so I checked it out...and it cost more than 200 yuan."

"It still costs money?" Yuan Ping'an was even more shocked, "What did you use to check the literature? PUBMED?"

"It's PUBMED." Sun Lien deliberately opened his payment interface and records, "The full text needs to be downloaded and paid."

Yuan Pingan glanced at Sun Li'en as if looking at a monster, "Are you really giving it?" After a pause for a few seconds, he suddenly laughed, "That's right, you probably haven't done much scientific research before, and you don't have many treasures. I’ve seen it before.” At this point, Yuan Ping’an pushed Sun Li’en away from the front of the computer very politely, and then began to type a URL on the keyboard with both hands, “Come on, let me show you a treasure.”

This feeling... a bit like the old days in college dorms.

"After you search for the literature you need from PUBMED, write down the PMID number, or the DOI number." Yuan Pingan handed over how Sun Lien bypassed the knowledge barriers of capitalism, "and then posted on this website Just type in..."

"What are you doing?" Xu Yourong didn't know when he arrived in the office, but the atmosphere of the "men's club" next to Sun Lien's desk was so strong that Xu Yourong himself was reluctant to approach, "The ones in our hospital The Internet access content is watched by the information department, don't say I didn't remind you, if you report criticism later, everyone will look bad."

"You must have used this website before." Yuan Ping'an said without turning his head, "Isn't it just to look at P and HUB, the information department can eat me?"

Xu Yourong was silent for a long time, "I remember this website cannot be accessed in China..."

Yuan Ping'an suddenly raised his head. He glanced at Xu Yourong who had an unusual expression, and then coughed, "I'm talking about PUBMED and SCI-HUB."

Xu Yourong left the office without saying a word, and Yuan Pingan continued to look down at the screen, as if nothing had happened.

Sun Lien lowered his head and wrote down the two websites Yuan Pingan mentioned, and asked after a while, "What you two just said...isn't it the same thing?"

　The more I write, the slower I write, and then I turn off the fire... I feel like I'm going to be bored to death
　　
　
(End of this chapter)