Xueba's Black Technology Simulator

Chapter 211 Telomerase

Lu Xiao's eyes were closed, and he was simulating countless small projects in his mind, looking for relevant documents he had read.

These days, Lu Xiao is not only reading some published papers, but also read a lot of unpublished papers in the laboratory.

In the copy, he came into contact with the biotechnology of 2030.

At that time, the biotechnology in Area 51 must have been the crystallization of the wisdom of countless top scientists in the Eagle Country.

Now in Lu Xiao's mind, the genetic evolution data that Tom Chen studied at the beginning appeared.

In this information, there is not much content about telomerase.

The main function of telomerase is to prolong the life of a cell so that it can replicate more times.

The genetic evolution that Tom Chen studied at the beginning was to let the cells develop greater potential and finally generate greater energy.

There are currently several directions or technical routes for human evolution. Some cells are too weak and need to be replaced with powerful cells, just like surgically removing certain organs and replacing them with more powerful ones.

But this method is difficult, and even if it succeeds, there will be serious consequences.

In many film and television works, there are mutated people.

Some have ugly faces, some have distorted facial features, extra arms and legs, skin like scales, and so on.

The reason for this is related to cells.

Humans have evolved to the present, and all cells are in a state of optimal balance, while some animals have evolved many different functions from humans due to the living environment.

For example, the teeth of sharks are very sharp, because sharks need such teeth to cut their prey, and the reason why human teeth have not evolved like sharks is also related to the living environment.

Evolution is related to the environment. According to natural evolution, humans may undergo some strange changes after millions of years.

For example, because of looking at mobile phones for a long time and working in the office, all of them became hunchbacks.

Due to genetic reasons, children's eyes appear myopia from the very beginning. The originally healthy vision, but inherited unhealthy myopia, the body thinks that myopia is a healthy state, so that people in the future will have to undergo surgical repair at birth.

What Lu Xiao has to do now is to artificially change this model, so that the state of natural evolution will be broken, and Lu Xiao will lead this process.

Among the naturally evolved animals, some have special organs, and now actively participating in this process is also going in these directions.

Lu Xiao can take the initiative to change the inside and outside of the body through the new arrangement and combination of cells, so that human beings can evolve.

This is one of the evolutionary lines.

But this route is not actually the route chosen by Tom Chen. Tom Chen chose the evolution from the inside.

Of course, even if you go the other way, simulating natural evolution and taking the risk of body mutation, you are actually targeting your genes.

But the path Tom Chen chose was easier and less risky.

It even refers to the cellular mechanism of ants.

Scientists have studied why ants can lift objects more than 1700 times their own body weight, and why ants have such great strength.

Is it because the ant's skin is relatively hard, and it is a hard shell that leads to greater strength?
Humans want to lift objects more than 1700 times, and they also need to change their skin into hard calcium cells instead of soft skin like ants.

Maybe scientists really thought so before they worked out the principle of ants lifting heavy objects.

But after studying ants, they discovered that the reason why ants have such great strength has to do with energy.

This is also the core of all living things.

Any living thing is inseparable from energy.

Scientists have found that the energy conversion rate of ants exceeds 80%. Compared with the highest technology of human beings, the conversion efficiency of aerospace engines is actually only 30-40%.

After careful study, scientists found that it is all related to ATP in the end.

Ants can lift heavy objects, because countless APTs burst out in the muscle cells in an instant.

The so-called ATP is a phosphorus-containing compound with a complex structure.

This special compound releases energy in the cell without generating heat, so its energy conversion rate is very high, because countless such small engines provide the ants with great power.

And humans naturally have this kind of thing too.

When translated, ATP is adenine nucleoside triphosphate, which is composed of adenine, ribose and three phosphate groups. It releases more energy when hydrolyzed, and is the most direct energy source in the body.

Human muscles also have this thing, and the energy needed by cells is provided by it.

There are about 50.7g of ATP in the human body, which can only sustain strenuous exercise for 0.3 seconds. ATP and ADP can be converted quickly to maintain a balance.

ADP is what appears after the hydrolysis of ATP, which can be imagined as charging and discharging.

ATP is hydrolyzed into ADP+Pi (free phosphate group)+energy. When ATP molecules are hydrolyzed, it actually refers to the hydrolysis of high-energy phosphate bonds in the ATP molecules.

Tom Chen took advantage of this. I don’t know if it was an accident or a special research. He changed the energy storage mode of the cells and increased the ATP content. When the burst broke out instantly, more energy would appear, allowing muscle cells to have more energy. energy into greater power.

Having experienced the feeling of genetic evolution, Lu Xiao knew that he just ran faster and had greater strength.

Doesn't actually seem to get any smarter.

There is an upper limit to this evolutionary method, that is, it depends on the muscles.

Are human muscles the same as those of ants?
Scientists have observed the microscopic structure of insect muscles and found that their muscles are the same as our human skeletal muscles and belong to "striated muscles". The basic structural unit and the horizontal stripes inside are also very similar to those of humans.

In other words, the most critical thing is ATP, and the amount of burst energy determines how much power it produces.

Of course body structure is also a determining factor.

If human skin is the same hard shell as lobsters and ants, then in the same ATP burst state, the power should be greater.

In the universe, maybe there really are lobstermen.

There was another movie in the past, District [-], which told the story of the Lobster Man.

Naturally, Lu Xiao doesn't need to pursue the limit, he must transform the skin into a hard shell, and pursue the greatest strength.

Only need to increase ATP, then the evolution of human strength and speed can be achieved.

When the strength is greater, the speed can naturally be increased. This is a very simple truth.

Our speed is also determined by the force exerted by our legs on the ground.

This is the core technology of Tom Chen's genetic evolution, which is to increase the ATP content in muscle cells and other cells. This is a very complex system.

It can be said that many cells have undergone a comprehensive transformation.

Transforming countless cells will inevitably lead to some mutations, and some mutations involve telomeres. When telomeres are changed, cancer will eventually appear.

Because the core feature of cancer is that it will replicate more times than normal cells, even reaching infinite replication, and the speed will be faster.

All of these are also different combinations of genes, and finally there are such consequences.

It can be said that human genes are similar to the codes in a computer. Different coding methods will produce different "programs".

Back to the topic, Lu Xiao is researching how to avoid gene mutations in specific medicines.

The most original point is to rule out the abnormality of telomerase!

Lu Xiao also discovered that it is very difficult to keep telomerase from being activated.

Because it doesn't have specific genes to control all this, or Lu Xiao hasn't studied it thoroughly, but there is actually a whole set of complicated system reasons.

It's just that the scope of DNA involved is very large, and any change in DNA may lead to the occurrence of telomerase and eventually cancer.

In fact, this is a normal phenomenon.

Otherwise why do so many people suffer from cancer?

Cancer is not a very rare disease among human diseases. Too many people suffer from cancer every year.

Lifestyle, diet, etc., can lead to cancer.

There is also the relationship between the environment, and a newly renovated house may also cause cancer.

This suggests that cells are also affected by chemical elements.

Many people near chemical plants, who smell the pungent smell, may also suffer from cancer, that is, cell mutation.

All that said this is very common.

In essence, it is external factors that change the normal living conditions and environment. Cells sense environmental changes, are stimulated by special chemical factors, and DNA also changes.

Eventually telomerase was activated, and tragedy struck.

Uncontrolled telomerase is a hidden time bomb in every cell.

It is about immortality, and it can also cause cancer, and then quickly end human life.

Lu Xiao rubbed his temples, he absorbed and digested too much technical information just now.

There are ants, ATP, and human cells.

Countless contents were spinning in Lu Xiao's mind.

This is different from storing in the simulator. The digested data is just like a normal person learning to read. After reading too many books and texts, a normal person will feel dizzy.

"Any change may activate telomerase. I have now changed the white blood cells of Deseros. Although I have not activated telomerase in these white blood cells, I have used the modified white blood cells on a large scale. In these white blood cells, over time, Sooner or later there will be abnormalities, as long as there is a problem with one white blood cell."

"Then it will replicate infinitely, and maybe it will also activate telomerase in other cells, countless cells will mutate, and then you will suffer from various cancers."

"It's not that Deiseros is completely healthy, it's that he hasn't exploded yet!" Lu Xiao muttered to himself.

This telomerase is really both an angel and a devil.

Lu Xiao began to analyze how to solve the problem.

He started from the fact that telomerase can make people live longer, and then he began to check the data in his mind, digested and even thought out a lot of information by himself.

To solve the problem now, it is not necessary to start with telomerase.

There are also many means.

For example, where there is cancer, we will eliminate it.

Kill all cancerous cells!

There are 37.2 trillion living cells in the human body, and these cells are dying and replicating every moment.

Any organ and tissue, even if there is cancerous cells, that is, abnormal telomerase, turns to fast replication and infinite replication.

To eliminate mutated cancer cells, there are also normal cells that can replace them.

If it doesn't work, you can also use normal cells to return to the ancestors to generate embryonic stem cells, and then use stem cells to induce the required cells and put them back where they should go.

This method is suitable for most cancers.

Only the core of the brain, if the cells in the brain become cancerous, then I am afraid that is the real big trouble.

After all, there is still relatively little research on the brain in human medical technology.

Surgery on the brain is very dangerous.

This is to eliminate "broken" cells as a whole.

Whether it is by surgery to remove bad cells, or by activating white blood cells to phagocytize damaged cells.

They are all methods of complete elimination.

There is another way, which is to solve it from the root cause.

That is the development of telomerase drugs.

Just restore telomerase to normal, or control telomerase. If you want it to be active, be active, and if you want it to be quiet, keep it quiet.

Then, mutated cancer cells can actually return to normal.

They were originally normal cells in the human body, but some functions were abnormal, and finally they did not obey the rules set by DNA, and began to damage the host's body and the entire ecological environment.

If DNA is the way of heaven in fantasy novels, then under the way of heaven, the operation mode of countless small cells is the various rules of the Three Thousand Ways.

And cancer cells are extraterritorial demons who break the rules.

Lu Xiao naturally wanted to solve the problem from telomerase. In this way, all cancer patients don't need to study what kind of cancer they are alone, and they don't need to do too many surgeries to match special genes and modify their white blood cells.

Simply injecting a drug that affects telomerase in all cells can silence the mutated cells.

As for treating cancer with normal methods, the technology that Lu Xiao has mastered can already treat most cancers.

He is afraid that there are some cancers that he cannot cure.

White blood cells are not omnipotent and can swallow all mutated cells.

Even white blood cells themselves may transform from dragon slayers to evil dragons.

Isn't that the case with leukemia?

There is also the dungeon world. Lu Xiao has a profound influence. Countless experts in 2030 can't cure his cancer. At that time, the experts must have the same technology as Lu Xiao now, or even a little bit ahead.

The biggest problem at that time was that Tom Chen's gene evolution medicine used by Lu Xiao caused ATP abnormality in a large number of cells. The range of influence was too large, and too many cells were affected. Each cell mutated, and the treatment method would be different.

Some cells are even irreplaceable and cannot be resolved by surgery or gene therapy.

In addition, the method of controlling telomerase is also related to longevity.

To control telomeres is to control the upper limit switch of cell division.

Now telomere is still the controller of cancer. There is nothing to study in the previous gene therapy, so Lu Xiao will research the gene drug controlled by telomerase next.

Only in this way, can Lu Xiao have the ability to solve the health problems that arise in Deseros or anyone in the future.

But Lu Xiao had no idea.

This is not chanting slogans, technology naturally comes to mind.

Need inspiration, need access to copy, need simulation points!

Lu Xiao is getting a little annoyed. There is no technology for special effects drugs, simulation points cannot be distributed, and other projects have no signs of completion, so there is no way to earn simulation points.

Without a simulation point, Lu Xiaozhen doesn't think he can overcome the research on telomerase.

This is about longevity.

And cancer controllers!
Even this problem can solve the sequelae of specific drugs.

It's like a Russian nesting doll, with a ring inside a ring.

Now that the quilts are tied together, Lu Xiao doesn't know how to untie them.

(End of this chapter)