Xueba's life simulator

Chapter 253 "Elixir"

After listening to Zhang Mingjie's explanation, Zhou Ming said to him: "It turns out that it's because of the 'mutant' thing. Is Dean Zhang interested in joining the research on 'mutant'?"

Zhang Mingjie hadn't yet said anything specific about why he came to see Zhou Ming, but Zhou Ming had instead invited Zhang Mingjie in advance.

"What? Is there a shortage of people in the research on the 'variant' of ancient viruses?" Seeing that Zhou Ming invited himself to participate in the research on the 'variant' so quickly, Zhang Mingjie asked a little strangely.

"Well, the main reason is that the research on 'variants' needs to be developed in parallel, and the development of drugs based on 'variants' will be developed later, so there is indeed a shortage of people." Zhou Ming explained to Zhang Mingjie.

Zhang Mingjie is a structural biologist, and he is mainly engaged in the research of structural biology, biochemistry and molecular biology. The range of biological talents needed for this research on "evolution" is also very wide. Zhang Mingjie, a Hua Guo If the academicians of the Academy of Sciences can join, it will also speed up Zhou Ming's successful research and development on "evolution".

"So fast? Although I know that the 'variant' is indeed very special, it can be said that it is a virus that has never been seen before, but you just returned to Luzhou yesterday, no matter how special the 'variant' is, there is no need to study it. Be in such a hurry!"

Seeing Zhou Ming say this, Zhang Mingjie was also a little surprised, after all, he was too anxious.

Although they already knew some characteristics of the "variant" when they were at the North Pole, the research time was not long after all.

In Zhang Mingjie's view, their understanding of this ancient virus is still far from enough. Under such circumstances, Zhou Ming actually mentioned the development of drugs based on "variants". Isn't this a joke?
"The speed is indeed faster, but our speed is not achieved by cutting corners and materials or cheating. We are developing multiple lines side by side and using a lot of manpower and material resources to achieve speed.

As for the research and development of drugs based on 'variants', I am sure that there will be no problems.

Don't you still believe me?Do you see any problems with the experimental projects I am responsible for, whether they are space synthetic organisms, food synthesis, or the recently launched cloned organs? "

Zhou Ming continued to persuade Zhang Mingjie.

"My main research is structural biology and neurocytology, such as the influence of protein structure on the nervous system. Even if you let me participate in the research on "variants", I'm afraid I can't contribute much. After all, my research on virology is not deep."

As an academician of biology, Zhang Mingjie naturally knows a lot about viruses, but because his research is not on viruses, he has neither rich experience nor rich cutting-edge knowledge in this area. , so he was asked to study viruses, which has nothing to do with his previous research direction.

And Zhang Mingjie said the same thing after listening to Zhou Ming's persuasion to him.

"Dean Zhang, I think the genetic modification of animals by 'variants' will definitely have an impact on nerve cells, for example, the impulse of one neuron is transmitted to another neuron or to the mutual contact between another cell. synapses, and the neurotransmitters they release.

Due to the particularity of 'variants', our research on variants cannot be limited to virology, and it is destined to be a cross-field where many biological disciplines intersect and blend.

Moreover, we want to carry out research and development of related drugs through 'variants', and we also need to understand its various characteristics and influences, especially in terms of nerve cells. "

After Zhang Mingjie finished speaking, Zhou Ming also said to Zhang Mingjie.

The reason why "mutant" drugs can comprehensively improve the physical fitness of human beings and make human beings cure or immunize many diseases that modern medical treatment is helpless is precisely because it involves a wide range of biological fields.

Otherwise, in the previous simulation world, such a future world with life science as the main development direction, it would not have taken so long to research "evolution" even under the leadership of Zhou Ming .

"The 'variant' will affect the nerve cells of the infected person? Are you sure?" After hearing Zhou Ming's words, Zhang Mingjie also asked in disbelief.

"This is also what I deduced based on the conditions shown in the experimental animals infected with the 'variant' before. The specifics will depend on the follow-up research. How is it? Are you interested?" Zhou Ming asked again.

"You said that, I am indeed interested, but I still have two or three projects on hand. Even if I am interested and want to join, I'm afraid I have extra time." Zhang Mingjie said.

"Aren't your two projects assigned to those doctoral students? If you feel that you don't have enough time, you can find a few more doctoral students to share your research tasks."

Hearing what Zhang Mingjie said, Zhou Ming said to him.

"Doctoral students are used to study small projects that are not so big, not so difficult, and not so important. If all my projects are entrusted to them, what use is it for me? ?

I'm not you, so I can be the shopkeeper directly. Whether you are a student or a researcher in your laboratory, if you ask you any questions during the experiment, you can solve them immediately.

If I don't participate in the project, if they encounter any problems during the experiment and ask me, I have to understand for a long time, let alone solve the problem. "

Hearing what Zhou Ming said so easily, Zhang Mingjie said a little speechlessly.

But not everyone is Zhou Ming, who knows all the experiments of all the experimental projects he set up. Whenever other people in the team encounter any problems, they can ask him to solve them. Zhang Mingjie is not so good.

Not to mention the biological experiment projects, but what Zhang Mingjie learned about Zhou Ming's doctoral student Liu Haowen when he was researching and proving Zhou's conjecture, if he encountered any problems, he would be able to solve them immediately.

May I ask if this is other tutors majoring in mathematics, students will ask the tutor if they don’t know how to solve the thesis topic, will the tutor know?

This tutor definitely doesn't know how to do it. If he knew it, he wouldn't let his graduate students choose this topic.

After hearing Zhang Mingjie's complaint, Zhou Ming just laughed, and didn't say anything about Zhang Mingjie's participation in the research on the "variant" of the ancient virus, but mentioned the medicine that will be researched based on the "variant" later.

"The drug I just said was developed based on the 'variant' is actually a genetic drug." Zhou Ming said to Zhang Mingjie.

"Gene drugs? Which disease are they being developed for?" Zhang Mingjie also asked after hearing Zhou Ming say that the drug to be developed based on the "variant" later was a genetic drug.

Zhang Mingjie also knows something about genetic medicine.

Genetic medicine usually consists of a carrier or delivery system containing engineered gene constructs, whose active ingredients can be DNA, RNA, genetically modified viruses, bacteria or cells, and by introducing foreign genes into target cells or tissues, replacing, compensating , Blocking and modifying specific genes to achieve the purpose of treating and preventing diseases.

Since what Zhou Ming is talking about here is a gene drug developed based on a "mutation", Zhang Mingjie thinks that the active ingredient is probably an "ancient" virus that has been genetically modified.

Genetic medicine can be said to be one of the most cutting-edge areas of drug development today. It has continuously made breakthrough progress in the treatment of genetic diseases, cancer, diabetes, and prevention of infectious diseases in recent years, especially a pharmaceutical research and development company owned by Future Biotechnology Company. and manufacturing production company, which alone has made it one of the top pharmaceutical companies in the world.

However, genetic drugs are highly selective, and one genetic drug is not suitable for all races. There are many differences in the genes of different races, and one genetic drug usually only targets one disease.

For example, Onpattro for familial amyloid polyneuropathy, Inclisiran for adult hypercholesterolemia and mixed dyslipidemia, Tegsedi for hereditary transthyretin amyloidosis, etc. Small nucleic acid drugs.

"The drug to be developed this time is different. I named it 'evolution'. It is different from the genetic disease treatment virus, oncolytic virus, gene editing drug, mRNA drug, small nucleic acid drug, etc. currently on the market. .

The technology used in the genetic drug mentioned this time is an innovative technology, and I think it is not accurate to call it a drug. "Zhou Ming said.

After being told by Zhou Ming, Zhang Mingjie became more and more interested in this kind of "evolution". He said to Zhou Ming: "Can't it be called a medicine? What should it be called? Health care products? You are so mysterious." It’s a lot, but it’s the key point.”

Faced with Zhang Mingjie's urging, Zhou Ming just smiled, and continued to say to him: "As the saying goes, medicine is three-point poisonous. The reason why medicine is medicine is because it is mainly used to cure diseases. People who are not sick take medicine. Undoubtedly, it will be considered as sick, and taking medicine if you are not sick is also very bad for your health.

However, 'evolution' is different.

You are sick, eating it can cure most of your body's diseases.

But even if you're not sick, there's no harm in eating it, and it can prevent diseases you don't have yet.

And whether you are sick or not, eating it can improve your physical fitness in an all-round way. "

After listening to what Zhou Ming said, Zhang Mingjie finally understood why Zhou Ming had not mentioned the key points just now. He was probably worried that he wouldn't believe it, because after Zhang Mingjie heard what Zhou Ming said, his first thought was indeed that he didn't believe what he said.

"Eating without illness can not only prevent many diseases, but also improve one's physical fitness in an all-round way?" Zhang Mingjie walked to Zhou Ming's side while talking, and stretched out his hand to touch Zhou Ming's forehead.

"I thought you came back to Luzhou from the North Pole, because the environment changed so much that your body was not used to it and you had a fever.

But I don't think you have a fever?How could you say such a thing?
No matter how hard you study the ancient virus, you still can't create such a medicine... No, it really shouldn't be called a medicine. If it really existed, it should be called an elixir.

No matter how much you study the ancient virus, you still can't get this 'elixir' out. "

This was the first time since Zhang Mingjie and Zhou Ming got acquainted, he felt that Zhou Ming was talking nonsense, and it was a serious nonsense.

"I already have an idea in my mind about the research and development of 'Evolution', but there are many things I can't tell you right now, so I can only tell you what I can say.

Would you like to stay and listen?
If you don't want to, you can just pretend that we haven't said what we said just now, and you can continue to talk about your coming to me.

I'll tell you about it now if you like. "

Zhou Ming said to Zhang Mingjie, because Zhang Mingjie is different from Li Zhizhi and Zhou Chunli, if he wants to talk about this matter with Zhang Mingjie, it will definitely be much more detailed than Li Zhizhi and the others.

After all, Zhang Mingjie himself studies biology, and he has a deeper understanding of this aspect than those before him.

Let's talk about it in detail, even if it is something that can be said, there is still a lot of content, so Zhou Ming asked Zhang Mingjie if he would like to listen.

"If you want to talk, of course I'm willing to listen."

Hearing what Zhou Ming said, Zhang Mingjie also wanted to hear what Zhou Ming had in mind. If Zhou Ming could really say something today, he would really hand over the projects he is currently working on to the doctoral students. The shopkeeper, or handing it over to other professors is also fine.

Seeing that Zhang Mingjie was willing to listen, Zhou Ming smiled with satisfaction.

Because Zhou Ming knows that as long as Zhang Mingjie is willing to listen, no matter how many projects he has on hand, he will definitely join in the research on "variants" later.

Next, Zhou Ming began to explain to Zhang Mingjie the professional knowledge related to the study of this ancient virus "mutation" and the "evolution" of genetic drugs.

Zhou Ming spoke very slowly, and Zhang Mingjie gradually changed from an attitude that it was okay to listen to it at the beginning, to being serious and focused. In the end, he was completely involved in it, and raised some doubts in his heart from time to time.

As for Zhou Ming's lecture, it took an afternoon.

"Wonderful, wonderful, really wonderful. If I didn't talk to you about professional knowledge in detail, I would never know how deep your understanding of various fields of biology is.

Now it seems that what I knew about you before was only a glimpse of a phoenix and a feather, and a glimpse of a leopard.

Say nothing, I would like to join the research on the 'variant', when will the research start?I'll organize the projects I'm working on tomorrow to free up time. "

After listening to Zhou Ming's speech, Zhang Mingjie said three things in succession, and finally asked Zhou Ming impatiently when the study started.

"Of course, the sooner the better, but Dean Zhang, you still have to deal with the projects on hand first, and don't mess up the projects you are currently researching because of this incident."

Seeing that Zhang Mingjie's performance was as he expected, Zhou Ming also said to him.

As for the purpose of Zhang Mingjie's coming here, he originally wanted to come to Zhou Ming to learn more about the "mutation" of the ancient virus. Now that he has learned enough, he doesn't need to ask Zhou Ming any more.

"We've been chatting for a long time, and it's getting late. Let's have dinner together?" Zhang Mingjie said to Zhou Ming again.

(End of this chapter)