Xueba's life simulator

Chapter 163
From the 24th, Zhou Ming began to often run between the school and the company, and he also spared time to read books every day. The time was really fulfilling.

In the past, when people studied aging, they had to study telomeres, but from about 2012 to now, telomere theory has not received much attention in the aging research industry.

Although there are still some people who pay attention to telomeres, they only study the role of telomeres on cells.

There are two main reasons why the research on telomeres has changed from being hot in the past to not paying much attention now.

One is that some scientists previously believed that only expressing telomerase could completely break the aging mechanism, just like cancer cells that can reproduce indefinitely.

But later scientists learned through research that the individual aging mechanism is not limited to telomeres, and only expressing telomerase cannot completely break the aging mechanism.

Now that it is known that telomeres do not determine lifespan, this has become an abandoned theory.

Another reason is that the telomere theory is not easy to commercialize, and there is no clear direction of development.

Because aging is not defined as a disease, telomeres are not easy to commercialize and can only be entrusted to diseases such as Alzheimer's disease for clinical use.

Therefore, the telomere theory cannot absorb money quickly, and cannot produce products such as health care products and facial masks, and the recovery of funds is slow.

Just like when some beauty products advertise, they will say that there are free radicals and the like, which can resist aging, but few beauty products advertise that their products are related to telomeres.

In addition, the telomere theory also has some unresolved problems, such as virus resistance, how to accurately and comprehensively extend telomeres and other issues.

After the telomere theory withdrew from the market, scientists studied more of the two aspects of free radical theory and epigenetics.

However, with the continuous development of epigenetics, even the free radical theory has been gradually withdrawn from the market.

So, what is epigenetics?
Epigenetics is a branch of genetics that studies the heritable changes in gene expression without changing the nucleotide sequence of the gene.

Epigenetics is a concept corresponding to genetics.

Genetics refers to changes in gene expression levels based on gene sequence changes, such as gene mutation, gene loss of heterozygosity, and microsatellite instability.

Epigenetics refers to changes in gene expression levels based on non-gene sequence changes, such as DNA methylation and chromatin conformation changes.

For example, why are you and your identical twin brother half of your genes from your mother and half from your father, but you two are not exactly the same in height, appearance and personality?
You know, as far as the current research shows, genes determine everything about us, including height, appearance and even personality.

According to this theory, we should all be the same as our twin siblings or older siblings.

This is related to epigenetics, just like some people say that this person ate well when he was a child, and he also exercised regularly, so he grew taller.

But in the same way, some people will say that a certain person’s family was poor when he was a child, the conditions were not good, and he didn’t eat well when he was a child, resulting in malnutrition, so he didn’t grow tall.

What these people are talking about here is not genes that affect height, but environment.

If everything a human being has was locked up by his own genes when he was born, then these changes would not be possible later.

How are genes expressed?

DNA is transcribed into RNA, and then protein is expressed, and the protein determines the traits.

That's why so many people think that as long as the genetic material is the same, the traits will be exactly the same.

The term epigenetics, in layman's terms, means that the expression of genes is also related to the external environment.

As for people's research on epigenetics and aging, it is mainly to use the environment that epigenetics refers to to affect gene expression, so as to slow down aging by changing the environment.

However, Zhou Ming's experiment on aging this time is going to prove that it is not as simple as epigenetics, but a combination of epigenetics, telomere theory, free radical theory and many other theories related to aging. He unifies these.

Although the aging project will not take longer than artificially synthesized food, it cannot be completed in a week or two. After all, if you need data, it will take a certain amount of time.

On the 25th, Zhou Ming started an experiment on artificially synthesized food in another laboratory of the school.

As for artificially synthesized food, the first thing Zhou Ming planned to do was artificially synthesized starch.

Now most of the teams' research on artificially synthesized starch is still synthesized by biological enzymes. In this process, a large amount of ATP and hydrogen are needed, and the price is even more expensive than artificially cultivated plant cells. Realized artificially synthesized starch, it is impossible to have practical value in a short time.

This method bypasses the cell membrane, the place where many biological reactions take place, which can greatly reduce sunlight loss and greatly increase the conversion rate.

However, the catalyst still needs to be synthesized by cells or artificially from DNA.

Although Zhou Ming's method did not bypass APT and biological enzymes, he had a way to artificially synthesize ATP and corresponding biological enzymes in large quantities.

With this method, the cost of artificial starch will drop dramatically.

When this method is really popularized, people no longer need to worry about food.

Although the quality of the food produced by this method may not be very good, at least it is healthy, and more importantly, it is cheap. The cost is at most transportation and labor. Food is provided free of charge to those who can afford it.

After artificially synthesizing starch, Zhou Ming plans to artificially synthesize glucose and fatty acids with carbon dioxide.

This uses carbon dioxide to synthesize glucose and fatty acid biosynthesis, which completely gets rid of biosynthesis.

However, Zhou Ming's experiments became more and he became busier.

On the 26th, Zhou Ming released an announcement to the outside world through the official website of the University of Science and Technology. This is an announcement to recruit experimental assistants.

It's impossible for Zhou Ming to borrow from other professors every time he does experiments in school like before, right?

You can't borrow people for nothing. Like the two people Zhou Ming borrowed from Yi Huaqing when he was at Metalworking University, Quanshuang and Geng Xu, they also gained a lot of benefits from Zhou Ming.

Besides, for HKUST, Zhou Ming borrowed manpower Lu Yongsi and Cheng Banxue from his mentor Bi Wanfang, and they naturally gained some benefits from Zhou Ming.

What's more, this is not a long-term solution.

[Recruitment notice for assistant in Professor Zhou Ming's laboratory of Huaguo University of Science and Technology]

This is the title of Zhou Ming's announcement. Click on the official website of the School of Biological Sciences of the University of Science and Technology of China to see the notice. This notice is very conspicuous.

"This research group has established a comprehensive research platform for research in various biological fields such as biosynthesis and cell senescence. Main research: (1) To find the best method for artificially synthesizing starch, to study... (2 )...

Job content:...

Recruitment conditions: ...

......"

Zhou Ming's recruitment notice is very clear, including the job content, the conditions that recruiters should meet, the working conditions and remuneration, and how to apply.

As for the introduction of the research group, Zhou Ming did not write it down.

Needless to say, the content of the job is naturally to assist in the experiment.

Zhou Ming said that the conditions for recruiting personnel are strict but not very strict. Undergraduates and postgraduates studying at the University of Science and Technology, as well as doctoral graduates from other schools are fine.

But if you want to say that it is not strict, you have to pass Zhou Ming's interview assessment, otherwise you will not be able to do it even if you are an excellent doctoral graduate from Qingbei.

As for the working conditions and remuneration, Zhou Ming himself was not the one who was short of money. In addition, the school gave him a lot of experimental funds as well as the experimental funds from his superiors. In terms of remuneration, Zhou Ming would definitely not treat these people badly.

However, overtime work is definitely necessary. If you want to produce results earlier, you have to work overtime.

But if Zhou Ming pays a lot of money, these people will not refuse to work overtime.

In today's China, why are many people unwilling to work overtime?
Isn't it still because of the treatment issue?

You have low wages and no overtime pay for overtime work. Who is willing to work overtime for you?
In other words, even if there is overtime pay for overtime work, but the pay is not much, you will still be scolded.

As the saying goes, with a monthly salary of 2000, your attitude towards work and overtime is "Boss, I am your father".

However, when your monthly salary is 5000, your attitude towards overtime and going to work is still not good. You still feel that the boss has a brain hole and will speak ill of the boss behind his back, but it will not be the same as before.

When your monthly salary reaches 1, although you still feel that there is something wrong with what the boss usually says, you won't say anything anymore.

When the monthly salary is 3, you will feel that whatever the boss says, you can just give the money.

When the monthly salary is 5, you will wish to work overtime every day.

With a monthly salary of 10, you want to live in the company.

With a monthly salary of 50, the company is your home.

With a monthly salary of 100 million, you choose the blue pill.

As for the application method, it is natural to send the application materials, that is, the resume to Zhou Ming's mailbox, and indicate "application for laboratory assistant" in the subject of the email.

The recruitment date did not indicate a specific time, only that it will be until the staff is filled.

The day after Zhou Ming's notice was sent out, he received a lot of emails, and students from the School of Biological Sciences of the University of Science and Technology personally came to his office to ask if they could join.

However, those who came to Zhou Ming's office were all undergraduates.

Graduate students follow their supervisors, and they can't finish the experiments. How can they have time to come to Zhou Ming to work part-time.

If those postgraduate students from the University of Science and Technology really came to Zhou Ming to do experiments, either their supervisors cooperated with Zhou Ming and transferred them here, or they changed their supervisors midway.

However, these are impossible things, especially the latter.

"Liu Yongxue, from the Department of Molecular Biology and Cell Biology. This year, you are a junior. Are you planning to find a job after graduating from your undergraduate degree, or are you planning to continue your graduate studies?"

In Zhou Ming's office, he was asking a third-year student from the Department of Molecular Biology and Cell Biology, School of Life Sciences, Faculty of Life Science and Medicine, HKUST who enrolled in 2013.

"I... I am going to continue my postgraduate study in this school."

This junior student named Liu Yongxue was a girl. At this time, when she answered Zhou Ming's question, her face was flushed, and she stumbled a bit when she spoke.

"You're not very fluent in speaking like this. You're not good at it. Wasn't it pretty good when you answered the question just now? Why do you seem to be more nervous now when I don't ask you a question?
Take it easy, I'm not a man-eating tiger.I should be a few years older than you, how old are you this year? "

Seeing that this third-year undergraduate student was fine when he answered his question just now, but now he was a little nervous talking to him, Zhou Ming was also a little curious.

After all, this is the HKUST student who came to him to interview the laboratory assistant today, the one who answered his various questions most satisfactorily.

How did Zhou Ming know that this junior girl had been paying attention to him since he came to school.

Her attention to Zhou Ming is like those star fans, except that those fans are chasing stars in the entertainment industry, while she is chasing Zhou Ming, a rising star in the academic world.

Now that she has met her idol, when she answered the professional knowledge question just now, she was fully focused on answering the question and not on Zhou Ming, so naturally she was not so nervous.

Now answering the nagging questions, her mind was on Zhou Ming again, so she naturally became nervous.

"It will be 22 in two days." Liu Yongxue replied.

"I am only 23 this year, and we are only one year apart. You don't have to be so nervous, just communicate with your classmates as usual.

If you still feel nervous, you can regard me as your senior.

The answers you gave just now are very good. Many things are not available in class. It can be seen from this that you must also read books often. Your knowledge is very wide, especially in molecular biology. many.

I am going to let you stay in the laboratory for a few days first, after all, you have done some experiments in your freshman and sophomore year.

If you perform well, you can stay in my laboratory and continue to work, and I will send you salary and so on. If you want to apply for my name in graduate school at your school, I can consider it later.

However, I want to explain in advance that no matter how many days you stay in my laboratory, as long as you agree to enter the laboratory, you must sign a non-disclosure agreement.

If you fail to abide by this non-disclosure agreement, not only will your future be cut off, but you may even be sent to jail.

So, whether you want to join or not depends on yourself, so go back and think about it first.Just give me an answer tomorrow. "

Zhou Ming said to Liu Yongxue again.

"Teacher Zhou, I am willing to join." After Zhou Ming said so much, Liu Yongxue did not hesitate to say yes after Zhou Ming finished speaking.

But this is also the case. With Zhou Ming's current identity here, no matter what kind of research, as long as he is the person in charge, there are too many people who want to join.

After Liu Yongshi agreed, Zhou Ming learned some basic information about her, and then let her leave.

Watching Liu Yongxue leave, Zhou Ming couldn't help sighing that students in good schools are different.

When he was in Metalworking University, Zhou Ming had never seen any student like Liu Yongxue.

However, such a person is rare even in HKUST.

At least judging from Zhou Ming's contact, as far as Liu Yongshi's performance is concerned today, he has seen a few of them like this when he was temporarily teaching in the junior class of HKUST.

(End of this chapter)